# AD/PD h-cutoff revision data package

This package accompanies the revised manuscript.

Contents:
- data_sources.csv: public datasets and portals used for the manuscript.
- hcutoff_edge_weights.csv: evidence-derived edge-weight table for AD/PD shared, AD-specific and PD-specific analyses.
- hcutoff_node_scores.csv: node-level backbone scores and final two-order h-cutoff Hub status.
- hcutoff_cutoffs.csv: one-order and two-order h-cutoff thresholds for each analysis scope.
- revision_summary.csv: summary of conceptual and methodological changes.
- scripts/h_cutoff_network.py: minimal Python implementation of the h-cutoff pipeline.
- scripts/reproduce_hcutoff_from_expression.R: R template for raw expression matrix reanalysis.
- figures/: figures inserted into the Word manuscript.

Important transparency note:
The attached tables are a compact, source-evidence-based reconstruction designed for manuscript revision and method demonstration in this offline environment. For publication, the provided scripts should be run against the full processed or raw matrices downloaded from GEO/refine.bio/SRA or the original authors' portals.
