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Advances in Radiotherapy
& Nuclear Medicine Advancements and challenges in radioactive iodine-125
a simulated needle pathway within the treatment area I-125 interstitial brachytherapy in immobilized malignant
(Figure 2). The treatment procedure includes preoperative tumors, a study demonstrated that the mean D90, V90,
planning, individualized 3D-printed template design and V100, V150, and seed number showed no significant
production, needle placement, I-125 seed implantation, difference between pre-operation and post-operation
and post-operative dosimetry verification, as illustrated values (P > 0.05) (the pre-operation vs. post-operation
in Figure 3. For 3D-printed personalized template-guided values were 94.96 ± 16.43% Gy vs. 91.97 ± 17.54% Gy,
Figure 1. Summary of the progress of iodine-125 brachytherapy in several important fields. NK cells: Natural killer cells; TME: Tumor microenvironment.
A B C
Figure 2. (A) 3D-printed template. (B) Three-dimensional reconstruction of a printed template. (C) The simulated needle pathway of the treatment area.
A B C
Figure 3. (A-C) The workflow of 3D-printed personalized template-assisted CT-guidance I-125 brachytherapy.
Volume 1 Issue 2 (2023) 3 https://doi.org/10.36922/arnm.0914
