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Brain & Heart Digital tools for stroke and bleeding risk in AF

combines factors from CHA2DS2-VASc and the doi: 10.1161/STROKEAHA.115.008711
intermountain risk score for patients with atrial fibrillation. 54. Liao JN, Chao TF, Kuo JY, et al. Global left atrial longitudinal
J Cardiovasc Electrophysiol. 2019;30(9):1452-1461. strain using 3-beat method improves risk prediction
doi: 10.1111/jce.13999 of stroke over conventional echocardiography in atrial
fibrillation. Circ Cardiovasc Imaging. 2020;13(8):e010287.
45. Engelsgjerd EK, Benziger CP, Horne BD. Validation of
the intermountain risk score and get with the guidelines- doi: 10.1161/CIRCIMAGING.119.010287
heart failure score in predicting mortality. Open Heart. 55. Melzi P, Tolosana R, Cecconi A, et al. Analyzing artificial
2021;8(2):e001722.
intelligence systems for the prediction of atrial fibrillation
doi: 10.1136/openhrt-2021-001722 from sinus-rhythm ECGs including demographics and
feature visualization. Sci Rep. 2021;11(1):22786.
46. Esteve-Pastor MA, Roldán V, Rivera-Caravaca JM, Ramírez-
Macías I, Lip GYH, Marín F. The use of biomarkers in doi: 10.1038/s41598-021-02179-1
clinical management guidelines: A critical appraisal. Thromb 56. Schulman S, Kearon C, Subcommittee on Control of
Haemost. 2019;119(12):1901-1919. Anticoagulation of the Scientific and Standardization
doi: 10.1055/s-0039-1696955 Committee of the International Society on Thrombosis
and Haemostasis. Definition of major bleeding in clinical
47. Rivera-Caravaca JM, Marín F, Vilchez JA, et al. Refining investigations of antihemostatic medicinal products in non-
stroke and bleeding prediction in atrial fibrillation by surgical patients. J Thromb Haemost. 2005;3(4):692-694.
adding consecutive biomarkers to clinical risk scores. Stroke.
2019;50(6):1372-1379. doi: 10.1111/j.1538-7836.2005.01204.x
doi: 10.1161/STROKEAHA.118.024305 57. Gage BF, Yan Y, Milligan PE, et al. Clinical classification
schemes for predicting hemorrhage: Results from the
48. Hu JR, Abdullah A, Nanna MG, Soufer R. The brain-heart National Registry of Atrial Fibrillation (NRAF). Am Heart
axis: Neuroinflammatory interactions in cardiovascular J. 2006;151(3):713-719.
disease. Curr Cardiol Rep. 2023;25(12):1745-1758.
doi: 10.1016/j.ahj.2005.04.017
doi: 10.1007/s11886-023-01990-8
58. Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJGM,
49. Kamel H, Elkind MSV, Bhave PD, et al. Paroxysmal Lip GYH. A novel user-friendly score (HAS-BLED) to assess
supraventricular tachycardia and the risk of ischemic stroke. 1-year risk of major bleeding in patients with atrial fibrillation:
Stroke. 2013;44(6):1550-1554. The Euro Heart Survey. Chest. 2010;138(5):1093-1100.
doi: 10.1161/STROKEAHA.113.001118 doi: 10.1378/chest.10-0134
50. Kamel H, Okin PM, Elkind MSV, Iadecola C. Atrial 59. Zhu W, He W, Guo L, Wang X, Hong K. The HAS-BLED
fibrillation and mechanisms of stroke: Time for a new score for predicting major bleeding risk in anticoagulated
model. Stroke. 2016;47(3):895-900. patients with atrial fibrillation: A systematic review and
doi: 10.1161/STROKEAHA.115.012004 meta-analysis. Clin Cardiol. 2015;38(9):555-561.
51. Maheshwari A, Norby FL, Roetker NS, et al. Refining doi: 10.1002/clc.22435
prediction of atrial fibrillation-related stroke using the 60. Fang MC, Go AS, Chang Y, et al. A new risk scheme to
P2-CHA2DS2-VASc score. Circulation. 2019;139(2):180-191. predict warfarin-associated hemorrhage: The ATRIA
doi: 10.1161/CIRCULATIONAHA.118.035411 (Anticoagulation and Risk Factors in Atrial Fibrillation)
Study. J Am Coll Cardiol. 2011;58(4):395-401.
52. Atrial Fibrillation Investigators: Atrial Fibrillation A
Anticoagulation Study; European Atrial Fibrillation Study; doi: 10.1016/j.jacc.2011.03.031
Stroke Prevention in Atrial Fibrillation Study; Boston Area 61. Apostolakis S, Lane DA, Guo Y, Buller H, Lip GYH.
Anticoagulation Trial for Atrial Fibrillation Study; Canadian Performance of the HEMORR(2)HAGES, ATRIA, and HAS-
Atrial Fibrillation Study; Veterans Affairs Prevention in BLED bleeding risk-prediction scores in patients with atrial
Atrial Fibrillation Study. Echocardiographic predictors of fibrillation undergoing anticoagulation: The AMADEUS
stroke in patients with atrial fibrillation: A prospective study (evaluating the use of SR34006 compared to warfarin or
of 1066 patients from 3 clinical trials. Arch Intern Med. acenocoumarol in patients with atrial fibrillation) study.
1998;158(12):1316-1320. J Am Coll Cardiol. 2012;60(9):861-867.
doi: 10.1001/archinte.158.12.1316 doi: 10.1016/j.jacc.2012.06.019
53. Yaghi S, Moon YP, Mora-McLaughlin C, et al. Left 62. Roldán V, Marín F, Fernández H, et al. Predictive value
atrial enlargement and stroke recurrence: The Northern of the HAS-BLED and ATRIA bleeding scores for the
Manhattan Stroke Study. Stroke. 2015;46(6):1488-1493. risk of serious bleeding in a “real-world” population with

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