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Brain & Heart                                                       ICU admission post-craniotomy for tumor


































            Figure 1. The current approach to post-operative care in elective craniotomy
            Abbreviations: ICU: Intensive care unit.

            4. Limitations and risks associated with ICU       approximately 30% of HAIs occurring in the ICU.  Post-
                                                                                                       49
            use                                                operative critical care is associated with an increased risk
                                                               of HAIs. Although infections in neurosurgical procedures
            4.1. Financial burden and limited resources        are uncommon,  certain factors can  predispose patients
                                                                                     50
            Healthcare system costs are constantly rising.  Although   to surgical site infections.  In a study of 317  patients
                                                 41
            the  ICU provides highly  specialized  patient  care  that is   undergoing cranial neurosurgery, the overall infection rate
            crucial for survival in selected cases, it often represents   was 7.2%, with most infections associated with the use of
            a significant economic burden. The lack of studies   extra-ventricular  drainage.  However,  extra-ventricular
            examining  ICU  cost-effectiveness  highlights  the  need   drainage is usually unnecessary in elective brain tumor
            for careful patient selection. 42,43  Craniotomies alone are   surgery.  In these cases, infections are normally caused by
                                                                     51
                                           41
            associated with high healthcare costs,  and the addition   skin flora, most commonly Staphylococcus. The bone flaps
            of ICU monitoring and management postoperatively can   created for cerebral access are avascular, making them prone
            further increase the financial burden. 44          to necrosis, inflammation, and post-operative infection.
              One effective strategy to address this challenge is an   Preferred management includes surgical debridement
            outpatient  craniotomy,  which  has  been  correlated  with  a   and removal of the bone flap with antimicrobial therapy.
            radical reduction in care costs when compared to inpatient   While the optimal duration of antibiotic treatment is not
            craniotomy.  Compared to outpatient care, inpatient   well  defined,  most studies  suggest  a  range  of 6  weeks  to
                     35
            procedures have been shown to incur an approximately six   12 months. 37
            times higher costs per unit/bed, whereas operating room,   4.3. Potential for adverse reactions to medication
            laboratory, and anesthesia expenses showed comparable   and treatments
            cost differences across intervention settings. Accordingly,
            outpatient-based neurosurgical brain tumor resection emerge   Post-operative management of patients undergoing
            as a safe and reasonable treatment option for appropriately   craniotomy usually includes: (1) pain management,
            selected patients, offering substantial global cost benefits. 45-48  (2) optimization of the PONV approach, (3) early oral
                                                               nutrition with gastrointestinal protection, (4) proper
            4.2. Increased risk of infection and prolonged     catheter management, and (5) early mobilization. These
            hospital stays                                     recommendations can be tailored to individual patient
            HAIs are a major public healthcare burden associated   needs. 52-54  However, adverse reactions to post-operative
            with more than 140,000 deaths worldwide each year, with   management  can affect patient  prognosis  and survival.


            Volume 3 Issue 1 (2025)                         5                                doi: 10.36922/bh.3802
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