Page 58 - EJMO-9-3
P. 58
Eurasian Journal of
Medicine and Oncology NOTCH3 in CSVD and breast cancer
breast cancer stem cells. Cancer Res. 2012;72(11):2768-2779. and downregulated by retinoic acid. J Cell Biochem.
2014;115(1):52-61.
doi: 10.1158/0008-5472.CAN-11-3567
doi: 10.1002/jcb.24632
110. Boelens MC, Wu TJ, Nabet BY, et al. Exosome transfer from
stromal to breast cancer cells regulates therapy resistance 121. Sabol HM, Amorim T, Ashby C, et al. Notch3 signalling
pathways. Cell. 2014;159(3):499-513. between myeloma cells and osteocytes in the tumour niche
doi: 10.1016/j.cell.2014.09.051 promotes tumour growth and bone destruction. Neoplasia.
2022;28:100785.
111. Studebaker AW, Storci G, Werbeck JL, et al. Fibroblasts
isolated from common sites of breast cancer metastasis doi: 10.1016/j.neo.2022.100785
enhance cancer cell growth rates and invasiveness 122. Ying J, Tsujii M, Kondo J, et al. The effectiveness of an anti-
in an interleukin-6-dependent manner. Cancer Res. human IL-6 receptor monoclonal antibody combined with
2008;68(21):9087-9095. chemotherapy to target colon cancer stem-like cells. Int J
doi: 10.1158/0008-5472.CAN-08-0400 Oncol. 2015;46(4):1551-1559.
112. Yamaguchi N, Oyama T, Ito E, et al. NOTCH3 signalling doi: 10.3892/ijo.2015.2851
pathway plays crucial roles in the proliferation of 123. Antony J, Tan TZ, Kelly Z, et al. The GAS6-AXL signalling
ErbB2-negative human breast cancer cells. Cancer Res. network is a mesenchymal (Mes) molecular subtype-
2008;68(6):1881-1888. specific therapeutic target for ovarian cancer. Sci Signal.
doi: 10.1158/0008-5472.CAN-07-1597 2016;9(448):ra97.
113. Huang TX, Guan XY, Fu L. Therapeutic targeting of the doi: 10.1126/scisignal.aaf8175
crosstalk between cancer-associated fibroblasts and cancer 124. Kent S, Hutchinson J, Balboni A, Decastro A,
stem cells. Am J Cancer Res. 2019;9(9):1889-1904. Cherukuri P, Direnzo J. ΔNp63α promotes cellular
114. Fernandez SV, Robertson FM, Pei J, et al. Inflammatory quiescence via induction and activation of Notch3. Cell
breast cancer (IBC): Clues for targeted therapies. Breast Cycle. 2011;10(18):3111-3118.
Cancer Res Treat. 2013;140(1):23-33. doi: 10.4161/cc.10.18.17300
doi: 10.1007/s10549-013-2600-4 125. Belin de Chantemèle EJ, Retailleau K, Pinaud F, et al.
115. Liu H, Wang J, Zhang M, et al. Jagged1 promotes aromatase Notch3 is a major regulator of vascular tone in cerebral
inhibitor resistance by modulating tumour-associated and tail resistance arteries. Arterioscler Thromb Vasc Biol.
macrophage differentiation in breast cancer patients. Breast 2008;28(12):2216-2224.
Cancer Res Treat. 2017;166(1):95-107. doi: 10.1161/ATVBAHA.108.171751
doi: 10.1007/s10549-017-4394-2 126. Kawai H, Kawaguchi D, Kuebrich BD, et al. Area-specific
116. Sousa S, Brion R, Lintunen M, et al. Human breast cancer regulation of quiescent neural stem cells by Notch3
cells educate macrophages toward the M2 activation status. in the adult mouse subependymal zone. J Neurosci.
Breast Cancer Res. 2015;17:101. 2017;37(49):11867-11880.
doi: 10.1186/s13058-015-0621-0 doi: 10.1523/JNEUROSCI.0001-17.2017
117. Cahill EF, Tobin LM, Carty F, Mahon BP, English K. Jagged-1 127. Loerakker S, Stassen OMJA, Ter Huurne FM, Boareto M,
is required for the expansion of CD4+ CD25+ FoxP3+ Bouten CVC, Sahlgren CM. Mechano sensitivity of
regulatory T cells and tolerogenic dendritic cells by murine Jagged-Notch signalling can induce a switch-type behavior
mesenchymal stromal cells. Stem Cell Res Ther. 2015;6:19. in vascular homeostasis. Proc Natl Acad Sci U S A.
2018;115(16):E3682-E3691.
doi: 10.1186/s13287-015-0021-5
doi: 10.1073/pnas.1715277115
118. Lamy M, Ferreira A, Dias JS, Braga S, Silva G, Barbas A.
Notch-out for breast cancer therapies. New Biotechnol. 128. Kitamoto T, Hanaoka K. Notch3 null mutation in mice
2017;39:215-221. causes muscle hyperplasia by repetitive muscle regeneration.
Stem Cells. 2010;28(12):2205-2216.
doi: 10.1016/j.nbt.2017.08.004
doi: 10.1002/stem.547
119. Charbonnier LM, Wang S, Georgiev P, Sefik E, Chatila TA.
Control of peripheral tolerance by regulatory T cell-intrinsic 129. Conboy IM, Rando TA. The regulation of Notch signalling
Notch signalling. Nat Immunol. 2015;16(11):1162-1173. controls satellite cell activation and cell fate determination
in postnatal myogenesis. Dev Cell. 2002;3(3):397-409.
doi: 10.1038/ni.3288
doi: 10.1016/s1534-5807(02)00254-x
120. Mezquita B, Mezquita J, Barrot C, et al. A truncated-Flt1
isoform of breast cancer cells is upregulated by Notch 130. Wei LK, Sutherland H, Au A, et al. A potential epigenetic
Volume 9 Issue 3 (2025) 50 doi: 10.36922/EJMO025150095

