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Global Health Econ Sustain                                    Interventional psychiatry: Disparities and solutions



            intensity for these participants during rTMS treatment.   Conflict of interest
            One study showed that there might be ethnic differences
            in response to deep TMS treatment, as they found a   The authors declare that they have no competing interests.
            greater clinical decrease in Quick Inventory of Depressive   Author contributions
            Symptomatology-16 scores among South Asians compared
            to their White counterparts (Sheth  et al., 2022). As   Conceptualization: Deepinder Nagra, Greg Appelbaum
            discussed earlier, given the significant racial disparity in   Writing – original draft: All authors
            participation observed in emerging psychedelic trials and   Writing – review & editing: All authors
            the identification of ethnic differences in outcomes, it is   Ethics approval and consent to participate
            crucial for researchers to prioritize diverse representation
            in clinical trials. This ensures that results are not   Not applicable.
            generalized to a broader population without considering a
            more diverse and inclusive participant base.       Consent for publication
              Recent initiatives by  the NIH  require  clinical   Not applicable.
            researchers to report their racial and ethnic demographics   Availability of data
            to promote diversity and inclusion; however, no such
            requirements exist for basic scientific research (Goldfarb &   Not applicable.
            Brown, 2022). Biomarker studies often rely on convenience
            samples consisting of university students and staff as the   References
            primary population of their research. However, since   AAMC. (2023). Report on Residents. Association of American
            many demographic groups, such as ethnic minorities and   Medical Colleges.  Available  from: https://www.aamc.
            members of lower SES, are underrepresented on college   org/data-reports/students-residents/data/report-
            campuses, the collected data is not entirely representative   residents/2022/table-b5-md-residents-race-ethnicity-and-
            of the general population (Dotson & Duarte, 2020).    specialty [Last accessed on 2023 Dec 12].
            Studies revealed that community-based involvement in   Appelbaum, L.G., Shenasa, M.A., Stolz, L., & Daskalakis, Z.
            trials results in a more diverse participant pool, leading   (2023).  Synaptic  plasticity and  mental  health:  Methods,
            to greater representation in community trials (Shea et al.,   challenges and opportunities.  Neuropsychopharmacology,
            2022). This implies that conducting more community-   48(1):113-120.
            based interventional trials, as opposed to solely relying on      https://doi.org/10.1038/s41386-022-01370-w
            academic medical institutions, can improve enrollment   Araya, R., Zitko, P., Markkula, N., Rai, D., & Jones, K. (2018).
            diversity.                                            Determinants of access to health care for depression in
                                                                  49 countries: A  multilevel analysis.  Journal of Affective
            4. Conclusion                                         Disorders, 234:80-88.
            Although efforts are being made to address concerns      https://doi.org/10.1016/j.jad.2018.02.092
            regarding  disparities  in  access  to  mental  health  care,   Asnis, G.M., Fink, M., & Saferstein, S. (1978). ECT in metropolitan
            inequities persist and continue to be a public health burden.   New York hospitals: A survey of practice, 1975-1976. The
            Because of the unique role of interventional therapies in   American Journal of Psychiatry, 135(4):479-482.
            the treatment of more severe, treatment-resistant illnesses,      https://doi.org/10.1176/ajp.135.4.479
            these inequities are amplified. Through awareness of these
            barriers and consideration of the solutions suggested   Axis Integrated Mental Health. TMS Therapy Costs Axis
            above, it may be possible to ameliorate these disparities and   Integrated Mental Health. Available from: https://axismh.
            broaden the reach and impact of this important branch of   com/home-page-2/tms-therapy-costs [Last accessed on
                                                                  2023 Sep 26].
            psychiatric care.
                                                               Bailey,  R.K., Mokonogho, J., & Kumar,  A. (2019),  Racial  and
            Acknowledgments                                       ethnic  differences  in  depression:  Current  perspectives.
                                                                  Neuropsychiatric Disease and Treatment, 15:603-609.
            None.
                                                                  https://doi.org/10.2147/NDT.S128584
            Funding                                            Bailine, S.H., & Rau, J.H. (1981). The decision to use ECT:
            This research was enabled by generous support from the   A retrospective study. Comprehensive Psychiatry, 22(3):274-281.
            Kreutzkamp Family Foundation.                         https://doi.org/10.1016/0010-440x(81)90085-7



            Volume 2 Issue 1 (2024)                         5                        https://doi.org/10.36922/ghes.2456
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