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Gene & Protein in Disease Cyanine and cancer therapy

apoptosis remains a significant topic necessitating further
exploration.
Acknowledgments

None.
Funding

This work has been financed by the National Natural
Science Foundation of China (No. 81870591), Key
Figure 8. Cyanine polymer nanoparticle compounds. These compounds R&D and Promotion Projects in Henan Province (Nos.
can induce cancer cell apoptosis through PDT and PTT, thus exerting 212102310874 and 222102310013), and Key Scientific
anti-tumor activity.
Research Projects of Colleges and Universities in Henan
In vivo experiments have validated that IR-808-ES enhances Province (No. 23A310011).
the efficacy of PDT/PTT treatment on HS by promoting Conflict of interest
apoptosis in HS tissue and facilitating the remodeling of
collagen fibers. Consequently, IR-808-ES holds promising The authors declare no conflicts of interest.
potential for clinical trials [233] . Author contributions
6. Conclusion Conceptualization: Yaqi Zhou, Xinying Ji, Lei Zhang

Cancer persists as the leading cause of mortality Visualization: Jiaheng Dong
globally, presenting a substantial challenge to humanity Writing – original draft: Chenguang Miao, Dong Feng
and imposing a significant socioeconomic burden on Writing – review & editing: Kunli Cui
countries. Despite the availability and significant progress Ethics approval and consent to participate
in various cancer treatment strategies, including those
approved for clinical use, chemotherapy continues to Not applicable.
stand as the most widely recognized therapeutic measure. Consent for publication
However, its utility is limited by a range of side effects, such
as hepatotoxicity, cardiotoxicity, and nephrotoxicity . Not applicable.
[8]
The principal focus of these treatment strategies revolves
around inducing the death of tumor cells, which can occur Availability of data
through various pathways, including apoptosis, necrosis, Not applicable.
autophagy, ferroptosis, copper-induced cell death, and
pyroptosis [208-210] . Recent endeavors in cancer treatment References
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Volume 2 Issue 4 (2023) 12 https://doi.org/10.36922/gpd.2486