Page 91 - GPD-3-1

Gene & Protein in Disease Stress-induced epigenetics of the DRD2 gene

116. Hill SY, Sharma VK. DRD2 methylation and regional grey doi: 10.1007/s00213-021-05968-8
matter volumes in young adult offspring from families at 126. Munn-Chernoff MA, Johnson EC, Chou YL, et al. Shared
ultra-high risk for alcohol dependence. Psychiatry Res genetic risk between eating disorder-and substance-
Neuroimaging. 2019;286:31-38.
use-related phenotypes: Evidence from genome-wide
doi: 10.1016/j.pscychresns.2019.03.006 association studies. Addict Biol. 2021;26(1):e12880.
117. Hillemacher T, Rhein M, Burkert A, et al. DNA- doi: 10.1111/adb.12880
methylation of the dopamin receptor 2 gene is altered 127. Braun CM, Chouinard MJ. Is anorexia nervosa
during alcohol withdrawal. Eur Neuropsychopharmacol. a neuropsychological disease? Neuropsychol Rev.
2019;29(11):1250-1257.
1992;3(2):171-212.
doi: 10.1016/j.euroneuro.2019.09.002
doi: 10.1007/BF01108842
118. Blum K, Baron D, Lott L, et al. In search of reward 128. Rask-Andersen M, Olszewski PK, Levine AS, et al.
deficiency syndrome (RDS)-free controls: The “Holy Grail” Molecular mechanisms underlying anorexia nervosa: Focus
in genetic addiction risk testing. Curr Psychopharmacol. on human gene association studies and systems controlling
2020;9(1):7-21.
food intake. Brain Res Rev. 2010;62(2):147-164.
119. Feltmann K, Borroto-Escuela DO, Rüegg J, et al. Effects of doi: 10.1016/j.brainresrev.2009.10.007
long-term alcohol drinking on the dopamine D2 receptor:
Gene expression and heteroreceptor complexes in the 129. Wang GJ, Volkow ND, Logan J, et al. Brain dopamine and
striatum in rats. Alcohol Clin Exp Res. 2018;42(2):338-351. obesity. Lancet. 2001;357(9253):354-357.
doi: 10.1111/acer.13568 doi: 10.1016/s0140-6736(00)03643-6
120. Blum K, Briggs AH, Elston SF, et al. Reduced leucine- 130. Frieling H, Römer KD, Scholz S, et al. Epigenetic
enkephalin--like immunoreactive substance in hamster dysregulation of dopaminergic genes in eating disorders.
basal ganglia after long-term ethanol exposure. Science. Int J Eat Disord. 2010;43(7):577-83.
1982;216(4553):1425-1427. doi: 10.1002/eat.20745
doi: 10.1126/science.7089531 131. Groleau P, Joober R, Israel M, Zeramdini N, DeGuzman R,
121. González B, Jayanthi S, Gomez N, et al. Repeated Steiger H. Methylation of the dopamine D2 receptor
methamphetamine and modafinil induce differential (DRD2) gene promoter in women with a bulimia-spectrum
cognitive effects and specific histone acetylation and DNA disorder: Associations with borderline personality
methylation profiles in the mouse medial prefrontal cortex. disorder and exposure to childhood abuse. J Psychiatr Res.
Prog Neuropsychopharmacol Biol Psychiatry. 2018;82:1-11. 2014;48(1):121-127.
doi: 10.1016/j.pnpbp.2017.12.009 doi: 10.1016/j.jpsychires.2013.10.003
122. Damez-Werno DM, Sun H, Scobie KN, et al. Histone arginine 132. Linnet J. The anticipatory dopamine response in
methylation in cocaine action in the nucleus accumbens. addiction: A common neurobiological underpinning
Proc Natl Acad Sci U S A. 2016;113(34):9623-9628. of gambling disorder and substance use disorder? Prog
Neuropsychopharmacol Biol Psychiatry. 2020;98:109802.
doi: 10.1073/pnas.1605045113
doi: 10.1016/j.pnpbp.2019.109802
123. Lepack AE, Werner CT, Stewart AF, et al. Dopaminylation
of histone H3 in ventral tegmental area regulates cocaine 133. Guerra RF, Batista IR, Kim HS, et al. Neuroimaging of
seeking. Science. 2020;368(6487):197-201. dopamine transporter density in the striatum of disordered
gamblers. J Gambl Stud. 2023;39(1):119-136.
doi: 10.1126/science.aaw8806
doi: 10.1007/s10899-021-10100-8
124. Nohesara S, Ghadirivasfi M, Barati M, et al.
Methamphetamine-induced psychosis is associated with 134. Hillemacher T, Frieling H, Buchholz V, et al. Alterations
DNA hypomethylation and increased expression of in DNA-methylation of the dopamine-receptor 2 gene are
AKT1 and key dopaminergic genes. Am J Med Genet B associated with abstinence and health care utilization in
Neuropsychiatr Genet. 2016;171(8):1180-1189. individuals with a lifetime history of pathologic gambling.
Prog Neuropsychopharmacol Biol Psychiatry. 2015;63:30-34.
doi: 10.1002/ajmg.b.32506
doi: 10.1016/j.pnpbp.2015.05.013
125. Zhang J, Fan Y, Zhou J, et al. Methylation quantitative
trait locus rs5326 is associated with susceptibility and 135. Staes, N, White CM, Guevara EE, et al. Chimpanzee
effective dosage of methadone maintenance treatment Extraversion scores vary with epigenetic modification of
for heroin use disorder. Psychopharmacology (Berl). dopamine receptor gene D2 (DRD2) and early rearing
2021;238(12):3511-3518. conditions. Epigenetics. 2022;17(12):1701-1714.

Volume 3 Issue 1 (2024) 18 https://doi.org/10.36922/gpd.1966