Page 7 - GPD-4-3

Volume 4 ǀ Issue 3 ǀ September 2025 ǀ

Gene & Protein in Disease

https://accscience.com/journal/GPD

CONTENTS

EDITORIAL
1 Circadian rhythms in Alzheimer’s disease: A molecular clock worth watching
Bivek Singh

REVIEW ARTICLES
2 Cathepsin proteases and cancer progression: A niche for dual-acting anticancer
therapeutics
Surinder M. Soond
3 TNFA gene polymorphisms and the risk of endometriosis: An updated meta-analysis of
genetic association studies
Amrit Sudershan, Showkat Ahmad Malik, Srishty Sudershan, Agar Chander Pushap, Mohd Anis Ganaie, Irfan Ahmad Bhat,
Feroze Ahmed Dar, Bashir Ahmad Sheikh, Mehraj Bashir, Showkat Ahmad Najar, Mohd Younis, Parvinder Kumar
4 Targeting the NLRP3 inflammasome using Chinese herbal medicine components for the
treatment of spinal cord injury
Parvaneh Behi Shahreza, Farzaneh Majidi, Shima Farajpour, Ghazaleh Moshkdanian
5 In situ spatial profiling: Gaining molecular and cellular insights within content and context
Shu-Ti Lin, Ian Molyneaux, Chen Yeh

PERSPECTIVE ARTICLE
6 Genetic pleiotropy between birth weight and adipose tissue regulation in determining the
risk of childhood obesity
Gianvincenzo Zuccotti, Valeria Calcaterra

ORIGINAL RESEARCH ARTICLES
7 Identification of cullin family members as novel diagnostic and prognostic biomarkers in
kidney renal clear cell carcinoma
Shaohao Liu, Fei Wang, Yange Wang, Dandan Wang, Shaoping Ji, Na Fang
8 Pre-addiction phenotype is associated with dopaminergic dysfunction: Evidence from 88.8
million genome-wide association study-based samples
Kenneth Blum, Alireza Sharafshah, Kai-Uwe Lewandrowski, Sérgio Luís Schmidt, Rossano Kepler Alvim Fiorelli, Albert
Pinhasov, Abdalla Bowirrat, Mark S. Gold, Eliot L. Gardner, Panayotis K. Thanos, Brian Fuehrlein, David Baron, Igor Elman,
Catherine A. Dennen, Nicole Jafari, Foojan Zeine, Alexander P.L. Lewandrowski, Milan Makale, Edward J. Modestino,
Keerthy Sunder, Kevin T. Murphy, Chynna Fliegelman, Shaurya Mahajan, Yatharth Mahajan, Rajendra D. Badgaiyan

MINI-REVIEW
9 The ABCA12 gene in Harlequin ichthyosis: Insights from bioinformatics and clinical research
Dorra Guermazi, Surya Khatri, Elias Guermazi, Elie Saliba

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