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Volume 4 ǀ Issue 2 ǀ June 2025 ǀ Page 1 – 108 ǀ
Global Translational Medicine
https://accscience.com/journal/gtm
CONTENTS
EDITORIAL
1 Adeno-associated virus as a powerful tool for gene therapy
Ling Yin
REVIEW ARTICLES
3 Revolutionizing drug response prediction: An unmet requirement for patients unresponsive
to precision medicine
Chen Yeh, Shu-Ti Lin, Andre Baranski, Sharon Yeh
12 Perspectives on the small ribonucleic acid drugs for pancreatic cancer
Qingqing Zhou, Guoan Shen, Huaying Li, Haimei Chen, Chang Liu
31 Superparamagnetic iron oxide nanoparticlebased nanosystems for cancer theranostics
Jnanranjan Panda, Dipanwita Das
PERSPECTIVE ARTICLE
51 YeeZzzy does it: Using Kanye West’s tweets to identify sleep and emotional disturbances
through digital rest-activity rhythms analysis
Matthew J. Reid, Darlynn M. Rojo-Wissar, Michelle Mei, Moira Differding, Michael T. Smith, Michael G. Smith
ORIGINAL RESEARCH ARTICLES
58 Luminal α-glucosidase inhibition improves insulin sensitivity and modulates glycemic and
lipid profiles in obese rats with type 2 diabetes mellitus
Orien L. Tulp, Syed A. A. Rizvi
71 Hepatocyte-specific angiotensinogen deficiency inhibits Western diet-induced liver steatosis
with suppression of cell division in mice
Alex C. Pettey, Dien Ye, Sohei Ito, Alan Daugherty, Hong S. Lu, Hisashi Sawada
86 Thyroid morphology and functional alterations in male and female rats with diet-induced
visceral obesity
Tatyana A. Mityukova, Anastasia A. Basalai, Tatyana E. Kuznetsova, Olga Y. Poluliakh, Mikita S. Kastsiuchenka
BRIEF REPORTS
96 A comparison of pathology examination and immunohistochemistry in studying pituitary
adenomas
Ach Taieb, El Arem Marwa, Abdessaied Nihed, Ach Koussay
103 Platelet aggregation inhibition by fluorophenylsubstituted 2-isoxazoline-5-carboxylic acids
and their derivatives
Mikalai M. Kauhanka, Marharita E. Parkhach, Svetlana N. Borisevich, Stanislava V. Glinnik, Elena N. Haluk
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