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Volume 4 ǀ Issue 2 ǀ June 2025 ǀ Page 1 – 108 ǀ

                                                                   Global Translational Medicine


                                                                             https://accscience.com/journal/gtm


           CONTENTS





            EDITORIAL
            1       Adeno-associated virus as a powerful tool for gene therapy
                    Ling Yin


            REVIEW ARTICLES
            3       Revolutionizing drug response prediction: An unmet requirement for patients unresponsive
                    to precision medicine
                    Chen Yeh, Shu-Ti Lin, Andre Baranski, Sharon Yeh
            12      Perspectives on the small ribonucleic acid drugs for pancreatic cancer
                    Qingqing Zhou, Guoan Shen, Huaying Li, Haimei Chen, Chang Liu
            31      Superparamagnetic iron oxide nanoparticlebased nanosystems for cancer theranostics
                    Jnanranjan Panda, Dipanwita Das


            PERSPECTIVE ARTICLE
            51      YeeZzzy does it: Using Kanye West’s tweets to identify sleep and emotional disturbances
                    through digital rest-activity rhythms analysis
                    Matthew J. Reid, Darlynn M. Rojo-Wissar, Michelle Mei, Moira Differding, Michael T. Smith, Michael G. Smith


            ORIGINAL RESEARCH ARTICLES
            58      Luminal α-glucosidase inhibition improves insulin sensitivity and modulates glycemic and
                    lipid profiles in obese rats with type 2 diabetes mellitus
                    Orien L. Tulp, Syed A. A. Rizvi
            71      Hepatocyte-specific angiotensinogen deficiency inhibits Western diet-induced liver steatosis
                    with suppression of cell division in mice
                    Alex C. Pettey, Dien Ye, Sohei Ito, Alan Daugherty, Hong S. Lu, Hisashi Sawada
            86      Thyroid morphology and functional alterations in male and female rats with diet-induced
                    visceral obesity
                    Tatyana A. Mityukova, Anastasia A. Basalai, Tatyana E. Kuznetsova, Olga Y. Poluliakh, Mikita S. Kastsiuchenka


            BRIEF REPORTS
            96      A comparison of pathology examination and immunohistochemistry in studying pituitary
                    adenomas
                    Ach Taieb, El Arem Marwa, Abdessaied Nihed, Ach Koussay
            103     Platelet aggregation inhibition by fluorophenylsubstituted 2-isoxazoline-5-carboxylic acids
                    and their derivatives
                    Mikalai M. Kauhanka, Marharita E. Parkhach, Svetlana N. Borisevich, Stanislava V. Glinnik, Elena N. Haluk







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