Page 60 - IMO-1-1
P. 60
Innovative Medicines & Omics Antioxidant nanomedicines for therapies
159. Xu C, Wang S, Wang H, et al. Magnesium-based therapeutics and protectors of normal tissue against oxidative
micromotors as hydrogen generators for precise rheumatoid injury. Antioxid Redox Signal. 2018;29(16):1691-1724.
arthritis therapy. Nano Lett. 2021;21(5):1982-1991.
doi: 10.1089/ars.2017.7453
doi: 10.1021/acs.nanolett.0c04438
170. Yang B, Shi J. Defect engineering of mesoporous silica
160. Hirst SM, Karakoti AS, Tyler RD, Sriranganathan N, Seal S, nanoparticles for biomedical applications. Accounts Mater
Reilly CM. Anti-inflammatory properties of cerium oxide Res. 2021;2(8):581-593.
nanoparticles. Small. 2009;5(24):2848-2856.
doi: 10.1021/accountsmr.1c00055
doi: 10.1002/smll.200901048
171. Garstang SV, Stitik TP. Osteoarthritis: Epidemiology, risk
161. Jeong HG, Cha BG, Kang DW, et al. Ceria nanoparticles factors, and pathophysiology. Am J Phys Med Rehabil.
fabricated with 6-aminohexanoic acid that overcome 2006;85(11 Suppl):S2-11; quiz S12-S14.
systemic inflammatory response syndrome. Adv Healthc doi: 10.1097/01.phm.0000245568.69434.1a
Mater. 2019;8(9):e1801548.
172. Sharma L, Kapoor D, Issa S. Epidemiology of osteoarthritis:
doi: 10.1002/adhm.201801548
An update. Curr Opin Rheumatol. 2006;18(2):147-156.
162. Kim J, Kim HY, Song SY, et al. Synergistic oxygen generation doi: 10.1097/01.bor.0000209426.84775.f8
and reactive oxygen species scavenging by manganese
ferrite/ceria co-decorated nanoparticles for rheumatoid 173. Altman RD. Osteoarthritis. Differentiation from
arthritis treatment. ACS Nano. 2019;13(3):3206-3217. rheumatoid arthritis, causes of pain, treatment. Postgrad
Med. 1990;87(3):66-72, 77-78.
doi: 10.1021/acsnano.8b08785
doi: 10.1080/00325481.1990.11704582
163. Roubenoff R, Freeman LM, Smith DE, Abad LW,
Dinarello CA, Kehayias JJ. Adjuvant arthritis as a model of 174. Lepetsos P, Papavassiliou AG. ROS/oxidative stress signaling
inflammatory cachexia. Arthritis Rheum. 1997;40(3):534-539. in osteoarthritis. Biochim Biophys Acta. 2016;1862(4):576-591.
doi: 10.1002/art.1780400320 doi: 10.1016/j.bbadis.2016.01.003
164. Xu C, Jiang Y, Wang H, et al. Arthritic microenvironment 175. McAlindon TE, Bannuru RR, Sullivan MC, et al. OARSI
actuated nanomotors for active rheumatoid arthritis guidelines for the non-surgical management of knee
therapy. Adv Sci (Weinh). 2023;10(4):e2204881. osteoarthritis. Osteoarthritis Cartilage. 2014;22(3):363-88.
doi: 10.1002/advs.202204881 doi: 10.1016/j.joca.2014.01.003
165. Guo L, Zhong S, Liu P, Guo M, Ding J, Zhou W. Radicals 176. Cheuk YC, Fu SC, Mok SW, Ho KK, Hung LK, Chan KM.
scavenging MOFs enabling targeting delivery of siRNA for Intra-articular injection of an antioxidant formulation did
rheumatoid arthritis therapy. Small. 2022;18(27):e2202604. not improve structural degeneration in a rat model of post-
traumatic osteoarthritis. J Orthop Translat. 2017;8:25-31.
doi: 10.1002/smll.202202604
doi: 10.1016/j.jot.2016.08.001
166. Yang B, Yao H, Yang J, Chen C, Shi J. Construction of a
two-dimensional artificial antioxidase for nanocatalytic 177. Elmali N, Esenkaya I, Harma A, Ertem K, Turkoz Y, Mizrak
rheumatoid arthritis treatment. Nat Commun. B. Effect of resveratrol in experimental osteoarthritis in
2022;13(1):1988. rabbits. Inflamm Res. 2005;54(4):158-162.
doi: 10.1038/s41467-022-29735-1 doi: 10.1007/s00011-004-1341-6
167. Batinic-Haberle I, Tovmasyan A, Spasojevic I. An 178. Natarajan V, Madhan B, Tiku ML. Intra-articular
educational overview of the chemistry, biochemistry and injections of polyphenols protect articular cartilage
therapeutic aspects of Mn porphyrins--from superoxide from inflammation-induced degradation: Suggesting
dismutation to H2O2-driven pathways. Redox Biol. a potential role in cartilage therapeutics. PLoS One.
2015;5:43-65. 2015;10(6):e0127165.
doi: 10.1016/j.redox.2015.01.017 doi: 10.1371/journal.pone.0127165
168. Tovmasyan A, Sheng H, Weitner T, et al. Design, 179. Howard MD, Hood ED, Zern B, Shuvaev VV, Grosser T,
mechanism of action, bioavailability and therapeutic Muzykantov VR. Nanocarriers for vascular delivery of
effects of mn porphyrin-based redox modulators. Med anti-inflammatory agents. Annu Rev Pharmacol Toxicol.
Princ Pract. 2013;22(2):103-130. 2014;54:205-226.
doi: 10.1159/000341715 doi: 10.1146/annurev-pharmtox-011613-140002
169. Batinic-Haberle I, Tovmasyan A, Spasojevic I. Mn porphyrin- 180. Gui T, Luo L, Chhay B, et al. Superoxide dismutase-loaded
based redox-active drugs: Differential effects as cancer porous polymersomes as highly efficient antioxidant
Volume 1 Issue 1 (2024) 54 doi: 10.36922/imo.2527

