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INNOSC Theranostics and
            Pharmacological Sciences                                     Spinal cord injury without radiological abnormalities



            6.6. Treatment decision                            SCI, such as DVT, fractures, gastric ulcers, heterotopic

            The treatment decision for SCIWORA in children is   ossification, or syringomyelia. To prevent these
            complex as it depends on various key factors, including:  complications, it is advisable to use the lowest spasticity
            i.   Age of the child                              medication that is effective, ensure the patient stays warm,
                                                                                                 [15,94]
            ii.  Severity of the injury                        and be mindful of cold weather conditions  .
            iii.  Time of symptoms onset                       6.8. Complications of SCI in children
            iv.  ASIA grade at the time of admission
            v.  Symptoms deterioration                         Complications resulting from SCI in younger children
            vi.  Patient stability and associated injuries     differ from those in adolescents and adults, necessitating
            vii.  Presence of deformity or other spine-affecting diseases  early prevention and intervention. Among younger
            viii. MOI                                          children with SCI, 96% developed scoliosis, 57% had hip
            ix.  Number of affected segments                   dysplasia, and 7% exhibited a latex allergy. In cases where
            x.  Presence of intradural, extradural, or both    injuries were at or above the T6 level, 34% experienced
            xi.  Appearance of edema, hematoma, or both.       autonomic dysreflexia, 41% developed pressure ulcers,
                                                               and  61%  suffered  from  spasticity,  particularly  in  the
            6.7. Rehabilitation procedure                      absence of bowel or bladder control. Notably, 82% were
            Rehabilitation techniques are designed to avoid secondary   on intermittent catheterization, and 69% were on a bowel
            effects, promote neurological recovery, and improve motor   program. Additional complications include hyperhidrosis,
            function. Once injury stabilization has been achieved,   kidney stones, ambulation, wheelchair dependence,
            the focus of rehabilitation shifts to preventing secondary   lifelong  growth  and  developmental issues,  and  various
            complications. In SCI patients, it is crucial to consider   secondary  complications,  such  as  decreased  bone
            the physical, neurological, emotional, and psychological   density, increased risk of fracture, muscle atrophy, and
            changes that arise during childhood and early adolescence.   cardiovascular impairments, all of which may arise from
                                                                  [29]
            This holistic approach, often referred to as the “medical   SCI . Complications such as pulmonary compromise,
            home,” is the most important and critical factor in the   pneumonia, urinary tract infection, gastrointestinal
            management of SCI . The ultimate goals of recovery   bleeding secondary to stress ulcers, DVT, decubitus ulcers,
                             [87]
            are  as follows:  (i)  Strengthening  everyday  independent   and even the risk of death pose significant challenges in
            life practices; (ii) facilitating adaptation to a new way of   the treatment of children with thoracic and lumbar spinal
                                                                         [95]
            life through recreational activities and household events;   cord lesions . Preventing DVT is helpful in reducing
            and (iii)  supporting  reintegration into  the  children’s   patient mortality and the risk of pulmonary embolisms.
            environment .  Home-based   interventions  during  Moreover, the early elevation of the patient’s head of the
                      [88]
            rehabilitation therapy have proven effective in promoting   bed is essential to prevent various respiratory-related
            the development of motor functions [89,90] . Following a SCI,   complications. These complications should be viewed as
            extensive practice, including over-ground practice, results   risks of SCI, emphasizing the need for early prevention and
            in significant recovery . In pediatric rehabilitation,   intervention throughout the rehabilitation process.
                               [91]
            numerous tools are available, but some present     6.9. Traditional Chinese medicine (TCM)
            disadvantages, particularly in young children. Achieving
            optimal recovery can be challenging, as it often requires   TCM is an important supplementary treatment in potentially
            a significant amount of space for assessment. In addition,   repairing  injured spinal  cords. Early implementation of
            item-based tasks can be time-consuming, and certain trials   TCM therapy has demonstrated effectiveness in improving
                                                                                          [96]
            may not be appropriate, especially for young children .   motor function in SCI patients . Six active natural
                                                        [92]
            Initiating early rehabilitation training following the   compounds found in herbs commonly used in TCM
            selected treatment method can help reduce the incidence   exhibit anti-inflammatory and antioxidant properties.
            of pressure sores, deep vein thrombosis (DVT), and other   These compounds have been shown to significantly reduce
            complications. This approach can also lead to a better   bleeding, edema, and necrotic tissue in the damaged area .
                                                                                                           [97]
            prognosis and improved outcomes . Spasticity following   Consequently, TCM can serve as an auxiliary therapy to
                                        [93]
                                                                                                 [98]
            SCI is a motor disorder characterized by increased muscle   promote functional recovery following SCI .
            tone with exaggerated tendon jerks. Some medications,   6.10. Post-treatment suggestions
            such as tizanidine, can cause hypotension and bradycardia,
            while  Clostridium botulinum works as a neuromuscular   Delays in symptom presentation and the potential for
            blocker. If the patient does not exhibit any changes, it is   recurrence pose significant risks in SCIWORA cases, and
            important to consider the secondary complications of   nursing management should be vigilant in this regard . To
                                                                                                         [99]

            Volume 7 Issue 1 (2024)                         6                         https://doi.org/10.36922/itps.1386
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