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Journal of Clinical and

                                                                  Translational Research



                                        EDITORIAL
                                        Clinical and translational medicine in the heart

                                        of JCTR



                                        Jacek Z. Kubiak *
                                                     1,2
                                        1 Institute of Genetics and Development of Rennes, UMR 6290, CNRS, Faculty of Medicine,
                                        University of Rennes, Rennes, France
                                        2 Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine – National
                                        Research Institute, Szaserow, 128, Warszawa, Poland




                                        1. Introduction
                                        The two main areas of medicine, namely clinical and translational medicine, are the
                                        primary focus of the Journal of Clinical and Translational Research (JCTR) – a journal that
                                        we wish would become the leading platform for dissemination and scientific exchange of
                                        medical discoveries and applications. The current issue features a collection of excellent
                                        articles covering the two above-mentioned areas, representative of the journal’s scope.
                                        This editorial will present an overview of the papers included in the current issue,
                                        highlighting the significance of the authors’ works.
                                        2. Scope and spectrum of our journalistic activity

                                        Rapidly developing biomedical research requires rapid worldwide dissemination, which
                                        aligns with JCTR’s main goal of delivering our content to the audience at the fastest
                                        speed possible. The content of our journal is very diverse since both key areas, namely
            *Corresponding author:      clinical medicine and translational medicine, are covered by the journal. Moreover, we
            Jacek Z. Kubiak
            (jacek.kubiak@univ-rennes.fr)  cover the whole spectrum of biomedical research from in silico and in vitro to in vivo and
                                        ex vivo studies conducted on both animal models and human patients. Epidemiologic
            Citation: Kubiak JZ. Clinical   studies also constitute a significant part of our articles, encompassing works at both the
            and translational medicine in the
            heart of JCTR. J Clin Transl Res.   regional and global levels. We believe having a diverse scope, covering works from a
            2025;11(1):1-3.             variety of medical and clinical specialties, is our strength to meeting multiple challenges
            doi: 10.36922/JCTR025090012   encountered at clinical settings.
            Received: February 26, 2025
                                        3. What can we find in the current issue of JCTR?
            Published online: March 4, 2025
                                        The original article “Dexamethasone in critical coronavirus disease-2019 cases: Insights
            Copyright: © 2025 Author(s).
            This is an open-access article   from a cross-sectional study” by Francine Johansson Azeredo and colleagues focuses on
            distributed under the terms of the   the survey of COVID-19 patients with comorbidities in Bahia, Brazil. Their findings
            Creative Commons AttributionNon-  contribute to the full description of the clinical course of SARS-CoV-2 infection. 1
            Commercial 4.0 International (CC
            BY-NC 4.0), which permits all   A commentary “Reprogramming of lipid droplets by host cells as a defense mechanism
            non-commercial use, distribution,
            and reproduction in any medium,   against viral infection”  by Chunfu Zheng from  the  University of  Calgary, Canada,
            provided the original work is   deals with the not-yet-well-explored virus-host interactions consisting of host cells
            properly cited.             reprograming of lipid droplets as a response to viral infection. The model system referred
            Publisher’s Note: AccScience   to in this paper is the porcine reproductive and respiratory syndrome virus (PRRSV) that
            Publishing remains neutral with   attacks the porcine alveolar macrophages (PAMs). This paper focuses on the role of the
            regard to jurisdictional claims in
            published maps and institutional   transcription factor YY1 in reprogramming lipid droplet content to promote resistance
            affiliations                to viral infection. 2




            Volume 11 Issue 1 (2025)                        1                          doi: 10.36922/JCTR025090012
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