Page 15 - AN-3-2
P. 15
Advanced Neurology Limbic-predominant TDP-43 encephalopathy
2023;4(3):e115-e125. encephalopathy neuropathologic changes and their role in
cognition and Alzheimer’s dementia in older persons. Acta
doi: 10.1016/S2666-7568(23)00019-3
Neuropathol Commun. 2021;9(1):156.
8. Duong MT, Wolk DA. Limbic-predominant age-related
TDP-43 encephalopathy: LATE-breaking updates in doi: 10.1186/s40478-021-01260-0
clinicopathologic features and biomarkers. Curr Neurol 18. Paganini-Hill A, Montine TJ, Bukhari SA, Corrada MM,
Neurosci Rep. 2022;22(11):689-698. Kawas CH, Sajjadi SA. LATE and potential estrogen-
doi: 10.1007/s11910-022-01232-4 related risk factors collected 30 years earlier: The 90+ study.
J Neuropathol Exp Neurol. 2023;82(2):120-126.
9. Wang SHJ, Guo Y, Ervin JF, Lusk JB, Luo S. Neuropathological
associations of limbic-predominant age-related TDP-43 doi: 10.1093/jnen/nlac119
encephalopathy neuropathological change (LATE-NC) 19. Dugan AJ, Nelson PT, Katsumata Y, et al. Analysis of genes
differ between the oldest-old and younger-old. Acta (TMEM106B, GRN, ABCC9, KCNMB2, and APOE)
Neuropathol. 2022;144(1):45-57. implicated in risk for LATE-NC and hippocampal sclerosis
doi: 10.1007/s00401-022-02432-5 provides pathogenetic insights: A retrospective genetic
association study. Acta Neuropathol Commun. 2021;9(1):152.
10. Boyle PA, Wang T, Yu L, et al. To what degree is late life
cognitive decline driven by age-related neuropathologies? doi: 10.1186/s40478-021-01250-2
Brain. 2021;144(7):2166-2175. 20. Cykowski MD, Arumanayagam AS, Powell SZ, et al. Patterns
doi: 10.1093/brain/awab092 of amygdala region pathology in LATE-NC: Subtypes
that differ with regard to TDP-43 histopathology, genetic
11. Nelson PT. LATE neuropathologic changes with little or risk factors, and comorbid pathologies. Acta Neuropathol.
no Alzheimer disease is common and is associated with
cognitive impairment but not frontotemporal dementia. 2022;143(5):531-545.
J Neuropathol Exp Neurol. 2021;80(7):649-651. doi: 10.1007/s00401-022-02416-5
doi: 10.1093/jnen/nlab050 21. Zhang L, Chen Y, Liu M, Wang Y, Peng G. TDP-43 and
limbic-predominant age-related TDP-43 encephalopathy.
12. Kapasi A, Yu L, Boyle PA, Barnes LL, Bennett DA,
Schneider JA. Limbic-predominant age-related TDP-43 Front Aging Neurosci. 2019;11:376.
encephalopathy, ADNC pathology, and cognitive decline in doi: 10.3389/fnagi.2019.00376
aging. Neurology. 2020;95(14):e1951-e1962.
22. Wu X, Peng C, Nelson PT, Cheng Q. Random forest-
doi: 10.1212/WNL.0000000000010454 integrated analysis in AD and LATE brain transcriptome-
13. Huang W, Zhou Y, Tu L, et al. TDP-43: From Alzheimer’s wide data to identify disease-specific gene expression. PLoS
disease to limbic-predominant age-related TDP-43 One. 2021;16(9):e0256648.
encephalopathy. Front Mol Neurosci. 2020;13:26. doi: 10.1371/journal.pone.0256648
doi: 10.3389/fnmol.2020.00026 23. Katsumata Y, Fardo DW, Shade LMP, Nelson PT. LATE-NC
14. Nag S, Barnes LL, Yu L, Wilson RS, Bennett DA, risk alleles (in TMEM106B, GRN, and ABCC9 genes)
Schneider JA. Limbic-predominant age-related TDP-43 among persons with African ancestry. J Neuropathol Exp
encephalopathy in Black and White decedents. Neurology. Neurol. 2023;82(9):760-768.
2020;95(15):e2056-e2064. doi: 10.1093/jnen/nlad059
doi: 10.1212/WNL.0000000000010602 24. Feng T, Lacrampe A, Hu F. Physiological and pathological
15. Sajjadi SA, Bukhari S, Scambray KA, et al. Impact and functions of TMEM106B: A gene associated with brain
risk factors of limbic predominant age-related TDP-43 aging and multiple brain disorders. Acta Neuropathol.
encephalopathy neuropathologic change in an oldest-old 2021;141(3):327-339.
cohort. Neurology. 2023;100(2):e203-e210. doi: 10.1007/s00401-020-02246-3
doi: 10.1212/WNL.0000000000201345 25. Prater KE, Latimer CS, Jayadev S. Glial TDP-43 and TDP-
16. Agrawal S, Yu L, Kapasi A, et al. Limbic-predominant age- 43 induced glial pathology, focus on neurodegenerative
related TDP-43 encephalopathy neuropathologic change proteinopathy syndromes. Glia. 2022;70(2):239-255.
and microvascular pathologies in community-dwelling doi: 10.1002/glia.24096
older persons. Brain Pathol. 2021;31(3):e12939.
26. Nag S, Schneider JA. Limbic-predominant age-related
doi: 10.1111/bpa.12939 TDP43 encephalopathy (LATE) neuropathological
17. Agrawal S, Yu L, Nag S, et al. The association of Lewy change in neurodegenerative diseases. Nat Rev Neurol.
bodies with limbic-predominant age-related TDP-43 2023;19(9):525-541.
Volume 3 Issue 2 (2024) 9 doi: 10.36922/an.2603

