Page 58 - AN-3-2
P. 58
Advanced Neurology Inflammation in diabetic stroke: Pathogenesis
Pathophysiology. 2010;17(3):197-218. by increasing LDL transcytosis across endothelial cells
via RAGE/NF-kappaB/Caveolin-1 pathway. Mol Med.
doi: 10.1016/j.pathophys.2009.12.001
2023;29(1):113.
8. Iadecola C, Buckwalter MS, Anrather J. Immune responses
to stroke: Mechanisms, modulation, and therapeutic doi: 10.1186/s10020-023-00715-5
potential. J Clin Invest. 2020;130(6):2777-2788. 20. Yu W, Tao M, Zhao Y, Hu X, Wang M. 4’-methoxyresveratrol
alleviated AGE-induced inflammation via RAGE-mediated
doi: 10.1172/JCI135530
NF-kappaB and NLRP3 inflammasome pathway. Molecules.
9. Mulnier HE, Seaman HE, Raleigh VS, et al. Risk of stroke 2018;23(6):1447.
in people with type 2 diabetes in the UK: A study using doi: 10.3390/molecules23061447
the general practice research database. Diabetologia.
2006;49(12):2859-2865. 21. Chawla D, Bansal S, Banerjee BD, Madhu SV, Kalra OP,
Tripathi AK. Role of advanced glycation end product
doi: 10.1007/s00125-006-0493-z
(AGE)-induced receptor (RAGE) expression in diabetic
10. Jebari-Benslaiman S, Galicia-Garcia U, Larrea-Sebal A, vascular complications. Microvasc Res. 2014;95:1-6.
et al. Pathophysiology of atherosclerosis. Int J Mol Sci.
2022;23(6):3346. doi: 10.1016/j.mvr.2014.06.010
22. Da Veiga GL, Della Nina Raffo MG, da Costa Aguiar Alves B,
doi: 10.3390/ijms23063346
Bacci MR, Fonseca FLA. NF-κB gene expression in
11. Libby P. The changing landscape of atherosclerosis. Nature. peripheral blood and urine in early diagnosis of diabetic
2021;592(7855):524-533. nephropathy - A liquid biopsy approach. Urine. 2019;1:24-28.
doi: 10.1038/s41586-021-03392-8 doi: 10.1016/j.urine.2020.05.005
12. Liu T, Zhang L, Joo D, Sun SC. NF-kappaB signaling in 23. Gromotowicz-Poplawska A, Kloza M, Aleksiejczuk M, et al.
inflammation. Signal Transduct Target Ther. 2017;2:17023. Nitric oxide as a modulator in platelet- and endothelium-
dependent antithrombotic effect of eplerenone in diabetic
doi: 10.1038/sigtrans.2017.23
rats. J Physiol Pharmacol. 2019;70(2).
13. Bentzon JF, Otsuka F, Virmani R, Falk E. Mechanisms of plaque
formation and rupture. Circ Res. 2014;114(12):1852-1866. doi: 10.26402/jpp.2019.2.02
24. Jamwal S, Sharma S. Vascular endothelium dysfunction:
doi: 10.1161/CIRCRESAHA.114.302721
A conservative target in metabolic disorders. Inflamm Res.
14. Mao R, Zong N, Hu Y, Chen Y, Xu Y. Neuronal death 2018;67(5):391-405.
mechanisms and therapeutic strategy in ischemic stroke. doi: 10.1007/s00011-018-1129-8
Neurosci Bull. 2022;38(10):1229-1247.
25. Tejero J, Shiva S, Gladwin MT. Sources of vascular nitric
doi: 10.1007/s12264-022-00859-0
oxide and reactive oxygen species and their regulation.
15. Sabitha Vadakedath VK. Role of advanced glycation end Physiol Rev. 2019;99(1):311-379.
products (AGE) in health and disease: An overview. Biochem
Physiol. 2018;7:246. doi: 10.1152/physrev.00036.2017
26. Stefano GB, Challenger S, Kream RM. Hyperglycemia-
doi: 10.4172/2168-9652.1000246
associated alterations in cellular signaling and dysregulated
16. Knott HM, Brown BE, Davies MJ, Dean RT. Glycation and mitochondrial bioenergetics in human metabolic disorders.
glycoxidation of low-density lipoproteins by glucose and low- Eur J Nutr. 2016;55(8):2339-2345.
molecular mass aldehydes. Formation of modified and oxidized
particles. Eur J Biochem. 2003;270(17):3572-3582. doi: 10.1007/s00394-016-1212-2
27. Brownlee M. Biochemistry and molecular cell biology of
doi: 10.1046/j.1432-1033.2003.03742.x
diabetic complications. Nature. 2001;414(6865):813-820.
17. Kheniser KG, Kashyap SR, Kasumov T. A systematic review: doi: 10.1038/414813a
The appraisal of the effects of metformin on lipoprotein
modification and function. Obes Sci Pract. 2019;5(1):36-45. 28. Juge-Aubry CE, Henrichot E, Meier CA. Adipose tissue:
A regulator of inflammation. Best Pract Res Clin Endocrinol
doi: 10.1002/osp4.309
Metab. 2005;19(4):547-566.
18. Indyk D, Bronowicka-Szydelko A, Gamian A, Kuzan A. doi: 10.1016/j.beem.2005.07.009
Advanced glycation end products and their receptors in serum
of patients with type 2 diabetes. Sci Rep. 2021;11(1):13264. 29. Bidulescu A, Dinh PC Jr., Sarwary S, et al. Associations of
leptin and adiponectin with incident type 2 diabetes and
doi: 10.1038/s41598-021-92630-0
interactions among African Americans: The Jackson heart
19. Shu M, Cheng W, Jia X, et al. AGEs promote atherosclerosis study. BMC Endocr Disord. 2020;20(1):31.
Volume 3 Issue 2 (2024) 8 doi: 10.36922/an.1683

