Page 56 - AN-4-2
P. 56

Advanced Neurology                                                     George Cotzias and L-DOPA therapy



            as well as Dr.  Nikolaos Lazaridis and Dr.  Anastasios      doi: 10.1002/mds.26120
            Mylonas for their assistance.                      8.   Ngwuluka N, Pillay V, Du Toit LC, et al. L-DOPA Delivery
                                                                  systems: Advancements in delivery of the gold standard.
            Funding                                               Expert Opin Drug Deliv. 2010;7:203-224.
            None.                                                 doi: 10.1517/17425240903483166
            Conflict of interest                               9.   Schulz JB, Hausmann L, Hardy J. 199  years of Parkinson
                                                                  disease-what have we learned and what is the path to the
            The authors declare that they have no competing interests.  future? J Neurochem. 2016;13(9 Suppl):3-7.
            Author contributions                                  doi: 10.1111/jnc.13733
                                                               10.  Albin LR, Leventhal KD. The missing, the short, and the
            Conceptualization: Konstantina Kotsaki                long: L-DOPA responses and dopamine actions. Ann Neurol.
            Writing–original draft: All authors                   2017;82:4-19.
            Writing–review & editing: All authors
                                                                  doi: 10.1002/ana.24961
            Ethics approval and consent to participate         11.  Berthet A, Bezard E. Dopamine receptors and L-DOPA-induced
                                                                  dyskinesia. Parkinsonism Relat Disord. 2009;15:S8-S12.
            Not applicable.
                                                                  doi: 10.1016/S1353-8020(09)70827-2
            Consent for publication                            12.  Bonner N, Bozzi S, Morgan L, et al. Patients’ experiences of

            Not applicable.                                       Parkinson’s disease: A qualitative study in glucocerebrosidase
                                                                  and idiopathic Parkinson’s disease. J Patient Rep Outcomes.
            Availability of data                                  2020;4(65):1-14.

            Not applicable.                                       doi: 10.1186/s41687-020-00230-9
                                                               13.  Encarnacion VE, Hauser AR. L-DOPA-induced dyskinesias
            References                                            in Parkinson’s disease: Etiology, impact on quality of life,
                                                                  and treatments. Eur Neurol. 2008;60:57-66.
            1.   Blonder  XL. Historical and  cross-cultural perspectives on
               Parkinson’s disease. J Complement Integr Med. 2018;15:1-15.     doi: 10.1159/000131893
               doi: 10.1515/jcim-2016-0065                     14.  Ferreira FFA, Meira M, Lemuchi ML, et al. Most Utilized rodent
                                                                  models for Alzheimer’s and Parkinson’s disease: A  critical
            2.   Fahn S. The medical treatment of Parkinson disease from   review of the past 5 years. Adv. Neurol. 2024;3(3):1-19.
               James Parkinson to George Cotzias. Mov Disord. 2015;30:4-18.
                                                                  doi: 10.36922/an.2903
               doi: 10.1002/mds.26102
                                                               15.  Feyder M, Bonito-Oliva A, Fisone G. L-DOPA-induced
            3.   Goldman GJ, Goetz GC. History of Parkinson’s disease.   dyskinesia and abnormal signaling in striatal medium
               Handb Clin Neurol. 2007;83:109-128.                spiny neurons: Focus on dopamine D1 receptor-mediated
               doi: 10.1016/S0072-9752(07)83005-3                 transmission. Front Behav Neurosci. 2011;5:71.
            4.   Fahn S. The 200-year journey of Parkinson disease:      doi: 10.3389/fnbeh.2011.00071
               Reflecting on the past and looking towards the future.   16.  Hornykiewicz  O. L-DOPA:  From  a biologically  inactive
               Parkinsonism Relat Disord. 2017;30:S1-S5.          amino acid to a successful therapeutic agent. Amino Acids.
               doi: 10.1016/j.parkreldis.2017.07.020              2002;23:65-70.
            5.   Goole J, Amighi K. L-DOPA delivery systems for the      doi: 10.1007/s00726-001-0111-9
               treatment of Parkinson’s disease: An overview. Int J Pharm.   17.  Juri C, Chana P. L-DOPA for Parkinson’s disease. What have
               2009;380:1-15.                                     we learned? (L-DOPA en la enfermedad de Parkinson. ¿Qué
               doi: 10.1016/j.ijpharm.2009.07.026                 hemos aprendido?). Rev Med Chil. 2006;134:893-901.
            6.   Hoehn MM, Yahr MD. Parkinsonism: Onset, progression   18.  Lew M. Overview of Parkinson’s disease. Pharmacotherapy.
               and mortality. Neurology. 1967;17(5):427-442.      2007;27:155S-160S.
               doi: 10.1212/wnl.17.5.427                          doi: 10.1592/phco.27.12part2.155S
            7.   Lees JA, Tolosa E, Olanow WC. Four pioneers of L-DOPA   19.  LeWitt AP, Fahn S. L-DOPA therapy for Parkinson disease:
               treatment: Arvid Carlsson, Oleh Hornykiewicz, George   A look backward and forward. Neurology. 2016;86:2-12.
               Cotzias, and Melvin Yahr. Mov Disord. 2014;30:19-36.     doi: 10.1212/WNL.0000000000002509


            Volume 4 Issue 2 (2025)                         50                               doi: 10.36922/an.5177
   51   52   53   54   55   56   57   58   59   60   61