Page 34 - ARNM-1-2
P. 34

Advances in Radiotherapy
            & Nuclear Medicine                                                            FAP-targeted RLT in cancer



               https://doi.org/10.1016/s0895-6111(00)00047-1      https://doi.org/10.2967/jnumed.123.265391
            65.  Gill MR, Falzone N, Du Y, et al., 2017, Targeted radionuclide   70.  Feig C, Jones JO, Kraman M, et al., 2013, Targeting CXCL12
               therapy in combined-modality regimens. Lancet Oncol, 18:   from FAP-expressing carcinoma-associated fibroblasts
               e414–e423.                                         synergizes with anti-PD-L1 immunotherapy in pancreatic
               https://doi.org/10.1016/S1470-2045(17)30379-0      cancer. Proc Natl Acad Sci U S A, 110: 20212–20217.
            66.  Chen H, Zhao L, Fu K, et al., 2019, Integrin alpha(v)beta(3)-     https://doi.org/10.1073/pnas.1320318110
               targeted radionuclide therapy combined with immune   71.  Zboralski D, Osterkamp F, Christensen E,  et al., 2023,
               checkpoint  blockade  immunotherapy  synergistically   Fibroblast activation protein targeted radiotherapy induces
               enhances anti-tumor efficacy. Theranostics, 9: 7948–7960.   an immunogenic tumor microenvironment and enhances
               https://doi.org/10.7150/thno.39203                 the efficacy of PD-1 immune checkpoint inhibition. Eur J
                                                                  Nucl Med Mol Imaging, 50: 2621–2635.
            67.  Choi J, Beaino W, Fecek RJ, et al., 2018, Combined VLA-
               4-targeted radionuclide therapy and immunotherapy in a      https://doi.org/10.1007/s00259-023-06211-6
               mouse model of melanoma. J Nucl Med, 59: 1843–1849.   72.  Fu H, Huang J, Sun L, et al., 2022, FAP-targeted radionuclide
               https://doi.org/10.2967/jnumed.118.209510          therapy of advanced radioiodine-refractory differentiated
                                                                  thyroid cancer with multiple cycles of 177 Lu-FAPI-46. Clin
            68.  Czernin J, Current K, Mona CE,  et al., 2021, Immune-  Nucl Med, 47: 906–907.
               checkpoint blockade enhances  Ac-PSMA617 efficacy in a
                                      225
               mouse model of prostate cancer. J Nucl Med, 62: 228–231.      https://doi.org/10.1097/RLU.0000000000004260
               https://doi.org/10.2967/jnumed.120.246041       73.  Rao Z, Zhang Y, Liu L,  et al., 2023,   177 LuLu-FAP-2286
                                                                  therapy in a case of right lung squamous cell carcinoma
            69.  Esfahani SA, De Aguiar Ferreira C, Summer P, et al., 2023,
               Addition of peptide receptor radiotherapy to immune   with systemic metastases. Eur J Nucl Med Mol Imaging, 50: 
               checkpoint inhibition therapy improves outcomes in   1266–1267.
               neuroendocrine tumors. J Nucl Med, 64: 1056–1061.      https://doi.org/10.1007/s00259-022-06048-5













































            Volume 1 Issue 2 (2023)                         13                      https://doi.org/10.36922/arnm.1667
   29   30   31   32   33   34   35   36   37   38   39