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Advances in Radiotherapy &

                                                                            Nuclear Medicine




                                        PERSPECTIVE ARTICLE
                                        Informed consent in radiation oncology:

                                        Adapting to the age of artificial intelligence



                                        Sorun Shishak 1  , Tejinder Kataria 1  , Susovan Banerjee * , Sameer Rastogi ,
                                                                                                           2
                                                                                         1
                                        Deepak Gupta , Shyam Singh Bisht 1  , Kushal Narang , Mayur Mayank 1  ,
                                                    1
                                                                                       1
                                                                                  3
                                        Gargi Sharma , Richa Arunendu , Varun Sheoran , and Abhishek Puri 4
                                                    1
                                                                    1
                                        1 Division of Radiation Oncology, Medanta The Medicity, Gurugram, Haryana, India
                                        2 Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India
                                        3 Department of Emergency Medicine, All India Institute of Medical Sciences, New Delhi, India
                                        4 Department of Radiation Oncology, Fortis Hospital, Mohali, Punjab, India
                                        Abstract

                                        The integration of artificial intelligence (AI) into radiation oncology is significantly
                                        enhancing  treatment precision and efficiency. However,  this technological
                                        advancement presents substantial ethical challenges, particularly in the context of
                                        informed consent. Traditional consent taking, which relies on physician discretion,
                                        must evolve to address the complexities introduced by AI systems. Key ethical
                                        considerations  include  ensuring  that  patients  understand  the role  of  AI in  their
                                        treatment, transparency in AI-driven decision-making processes, and the protection
                                        of patient privacy. A refined approach to informed consent is necessary to navigate
            *Corresponding author:      these challenges. This approach should prioritize clear communication, emphasize
            Susovan Banerjee
            (drsusovan@gmail.com)       the complementary role of AI in treatment and the decision-making process, and
                                        address potential biases inherent in AI algorithms.
            Citation: Shishak S, Kataria T,
            Banerjee S, et al. Informed consent
            in radiation oncology: Adapting to   Keywords: Artificial intelligence; Radiation oncology; Consent; Oncology
            the age of artificial intelligence.
            Adv Radiother Nucl Med.
            2025;3(3):30-33.
            doi: 10.36922/ARNM025250030
            Received: June 16, 2025     1. Introduction
            Revised: July 25, 2025      The field of oncology is witnessing transformative changes with the introduction of
                                        artificial intelligence (AI), which aids in diagnosing cancers,  developing personalized
                                                                                        1-3
            Accepted: August 5, 2025
                                                     4,5
                                                                                       6
                                        treatment plans,  and predicting treatment outcomes.  AI has rapidly become
            Published online: August 18, 2025  integrated into  key aspects of  our practice, from  automated  contouring of  gross
                                                    7
                                                                        8
            Copyright: © 2025 Author(s).   tumor volume,  clinical target volumes,  and organs at risk,  to plan optimization and
                                                                                        7
            This is an Open-Access article   adaptive radiotherapy,  offering remarkable efficiency and accuracy in treatment.
                                                          9,10
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            distributed under the terms of the
            Creative Commons Attribution   These AI-powered tools in radiation oncology are designed to optimize patient care.
            License, permitting distribution,   However, the involvement of AI raises complex ethical questions, particularly regarding
            and reproduction in any medium,   patient consent. In the past, consent was primarily based on physician judgment and
            provided the original work is
            properly cited.             patient understanding. However, these technologies can introduce additional layers of
                                        complexity to the consent process, as AI’s involvement complicates this dynamic.
            Publisher’s Note: AccScience
            Publishing remains neutral with   Patients must be informed about the AI-driven components involved. It is essential
            regard to jurisdictional claims in
            published maps and institutional   for them to understand that while AI can enhance the precision of radiation therapy, the
            affiliations.               decision-making process remains under the oversight of human professionals. Ensuring
            Volume 3 Issue 3 (2025)                         30                        doi: 10.36922/ARNM025250030
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