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Brain & Heart A mini-review on heart-brain communication
Appendix
Video A1. The electrical transmission from the brain to the intrinsic cardiac nervous system (ICNS) occurs through vagus
nerve. In response to this signal from the brain, ICNS release acetylcholine, which regulates the autonomic functions of the
heart, resulting in beat-to-beat variation in heart rhythm, explained by heart rate variability (HRV). HRV is correlated with
heartbeat-evoked potential (HEP) amplitudes. Environmental factors influence HRV and hence can indirectly affect HEP
amplitudes, thereby affecting heart-brain communication.
Volume 2 Issue 2 (2024) 10 doi: 10.36922/bh.2901

