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Brain & Heart Digital tools for stroke and bleeding risk in AF

History. No LVEF criterion

DOAC (2023)

GARFIELD‑AF (2017) Carotid occlusive disease, history of CAD or PAD, pulse

ORBIT (2015)

Defined as any prior outpatient or inpatient ICD-9 diagnosis code of hemorrhage, including by specific organ system intracranial or gastrointestinal bleeding), in the (e.g., all-cause prior bleeding), and by timing (within 90 days or >90 days) eGFR: Estimated glomerular filtration rate; ESRD: End-stage renal disease; Hb: Hemoglobin; INR: International normalized ratio; LVEF: Left ventricular

ATRIA (2011) (e.g., prior aggregate Abbreviations: ALP: Alkaline phosphatase; ALT: Alanine transaminase; AST: Aspartate transaminase; BMI: Body mass index; CAD: Coronary artery disease; CKD: Chronic kidney disease;

HAS‑BLED (2010) Major bleeding refers to any bleeding requiring hospitalization and/or causing a decrease in hemoglobin level of >2 g/L and/or requiring blood transfusion that was not a hemorrhagic stroke anti-inflammatory; PAD: Peripheral artery disease; TIA: Transient ischemic attack; ULN: Upper limit of normal; ✔: Variable used in scoring.

HEMORR2HAGES (2006) Variables defined based on ICD-9-CM Codes from baseline hospitalization

Table 2. (Continued) Factors Heart failure Additional factors Additional definitions

Volume 2 Issue 3 (2024) 9 doi: 10.36922/bh.3068