Page 98 - BH-3-3
P. 98

Brain & Heart                                                         DIO2 in malformed cerebrovasculature



               mouse model of cerebral cavernous malformations. Stroke.      doi: 10.1038/nrcardio.2016.174
               2025;56(4):1010-1025.
                                                               12.  Fukunaga K. Refractory gastrointestinal bleeding treated
               doi: 10.1161/strokeaha.124.049935                  with thyroid hormone replacement.  J  Clin Gastroenterol.
                                                                  2001;33:145-147.
            8.   Fish JE, Flores Suarez CP, Boudreau E, et al. Somatic Gain
               of KRAS function in the endothelium is sufficient to cause      doi: 10.1097/00004836-200108000-00011
               vascular malformations that require MEK but Not PI3K   13.  Comi AM, Bellamkonda S, Ferenc LM, Cohen BA,
               signaling. Circ Res. 2020;127(6):727-743.
                                                                  Germain-Lee EL. Central hypothyroidism and sturge-weber
               doi: 10.1161/circresaha.119.316500                 syndrome. Pediatr Neurol. 2008;39(1):58-62.
            9.   Di Carlo SE, Peduto L. The perivascular origin of pathological      doi: 10.1016/j.pediatrneurol.2008.03.018
               fibroblasts. J Clin Invest. 2018;128(1):54-63.
                                                               14.  Zhang H, Li B, Huang Q, et al. Mitochondrial dysfunction
               doi: 10.1172/jci93558                              induces  ALK5-SMAD2-mediated  hypovascularization
                                                                  and arteriovenous malformations in mouse retinas.  Nat
            10.  Chen K, Cheong LY, Gao Y,  et al. Adipose-targeted
               triiodothyronine  therapy  counteracts  obesity-related   Commun. 2022;13(1):7637.
               metabolic complications and atherosclerosis with negligible      doi: 10.1038/s41467-022-35262-w
               side effects. Nat Commun. 2022;13(1):7838.
                                                               15.  Shi D, Qi M, Zhou L,  et al. Endothelial mitochondrial
               doi: 10.1038/s41467-022-35470-4                    preprotein translocase tomm7-rac1 signaling axis dominates
                                                                  cerebrovascular network homeostasis. Arterioscler Thromb
            11.  Jabbar A, Pingitore A, Pearce SHS, Zaman A, Iervasi G,
               Razvi S. Thyroid hormones and cardiovascular disease. Nat   Vasc Biol. 2018;38(11):2665-2677.
               Rev Cardiol. 2017;14(1):39-55.                     doi: 10.1161/atvbaha.118.311538


















































            Volume 3 Issue 3 (2025)                         4                            doi: 10.36922/BH025150018
   93   94   95   96   97   98   99   100