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Design+ ML for predicting Alzheimer’s progression

Table A2. Classification report of diagnosis classifiers
Diagnosis classifier Classification report
Medical history Precision Recall F1-score Support
variables HC 0.60 0.80 0.68 69
MCI 0.09 0.04 0.06 24
AD 0.25 0.11 0.15 18
Macro-average 0.31 0.32 0.30 111
Confusion matrix
55 10 4
21 1 2
16 0 2
Neuropsychological Precision Recall F1-score Support
assessment variables HC 0.97 0.93 0.95 84

MCI 0.69 0.89 0.77 27
AD 0.95 0.78 0.86 23
Macro-average 0.87 0.87 0.86 134
Confusion matrix
78 6 0
2 24 1
0 5 18
Blood analysis and Precision Recall F1-score Support
ApoE genotype HC 0.78 0.85 0.81 107
variables
MCI 0.19 0.14 0.16 22
AD 0.47 0.37 0.41 19
Macro-average 0.48 0.45 0.46 148
Confusion matrix
91 11 5
16 3 3
10 2 7
Abbreviations: AD: Alzheimer’s disease; ApoE: Apolipoprotein
E; HC: Healthy control; MCI: Mild cognitive impairment.

Volume 2 Issue 3 (2025) 14 doi: 10.36922/DP025270031