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Eurasian Journal of
Medicine and Oncology Gut microbiome effects on obesity

doi: 10.1038/s41587-023-01818-4 diets: The POUNDS lost trial. Liver Int. 2022;42(2):363-373.
170. Stinson LF, Geddes DT. Microbial metabolites: The next doi: 10.1111/liv.15098
frontier in human milk. Trends Microbiol. 2022;30(5):408-410. 180. Calderon G, McRae A, Rievaj J, et al. Ileo-colonic delivery
doi: 10.1016/j.tim.2022.02.007 of conjugated bile acids improves glucose homeostasis via
colonic GLP-1-producing enteroendocrine cells in human
171. Stinson LF, Gay MCL, Koleva PT, et al. Human milk from
atopic mothers has lower levels of short chain fatty acids. obesity and diabetes. EBioMedicine. 2020;55:102759.
Front Immunol. 2020;11:1427. doi: 10.1016/j.ebiom.2020.102759
doi: 10.3389/fimmu.2020.01427 181. De Silva A, Bloom SR. Gut hormones and appetite control:
A focus on PYY and GLP-1 as therapeutic targets in obesity.
172. Xi M, Yan Y, Duan S, Li T, Szeto IMY, Zhao A. Short-chain Gut Liver. 2012;6(1):10-20.
fatty acids in breast milk and their relationship with the
infant gut microbiota. Front Microbiol. 2024;15:1356462. doi: 10.5009/gnl.2012.6.1.10

doi: 10.3389/fmicb.2024.1356462 182. Mullish BH, Pechlivanis A, Barker GF, Thursz MR,
Marchesi JR, McDonald JAK. Functional microbiomics:
173. Krolenko EV, Kupriyanova OV, Nigmatullina LS, Evaluation of gut microbiota-bile acid metabolism
Grigoryeva TV, Roumiantsev SA, Shestopalov AV. Changes interactions in health and disease. Methods. 2018;149:49-58.
of the concentration of short-chain fatty acids in the
intestines of mice with different types of obesity. Bull Exp doi: 10.1016/j.ymeth.2018.04.028
Biol Med. 2024;176(3):347-353. 183. Wahlström A, Aydin Ö, Olsson LM, et al. Alterations in
doi: 10.1007/s10517-024-06022-1 bile acid kinetics after bariatric surgery in patients with
obesity with or without type 2 diabetes. EBioMedicine.
174. Akhgarjand C, Tavakoli A, Samavat S, et al. The effect of 2024;106:105265.
conjugated linoleic acid supplementation in comparison
with omega-6 and omega-9 on lipid profile: A graded, doi: 10.1016/j.ebiom.2024.105265
dose-response systematic review and meta-analysis of 184. Zhen J, Zhou Z, He M, et al. The gut microbial metabolite
randomized controlled trials. Front Nutr. 2024;11:1336889. trimethylamine N-oxide and cardiovascular diseases. Front
doi: 10.3389/fnut.2024.1336889 Endocrinol. 2023;14:1085041.
175. Yu H, Zou ZX, Wei W, Li Y. Conjugated linoleic acid doi: 10.3389/fendo.2023.1085041
reduces lipid accumulation via down-regulation expression 185. Papandreou C, Moré M, Bellamine A. Trimethylamine
of lipogenic genes and up-regulation of apoptotic genes in N-oxide in relation to cardiometabolic health-cause or
grass carp (Ctenopharyngodon idella) adipocyte in vitro. effect? Nutrients. 2020;12(5):1330.
Biotechnol. 2024;26(1):169-180.
doi: 10.3390/nu12051330
doi: 10.1007/s10126-024-10286-z
186. Gessner A, di Giuseppe R, Koch M, Fromm MF, Lieb W, Maas R.
176. Ryder JW, Portocarrero CP, Song XM, et al. Isomer-specific Trimethylamine-N-oxide (TMAO) determined by LC-MS/MS:
antidiabetic properties of conjugated linoleic acid. Improved distribution and correlates in the population-based PopGen
glucose tolerance, skeletal muscle insulin action, and UCP-2 cohort. Clin Chem Lab Med. 2020;58(5):733-740.
gene expression. Diabetes. 2001;50(5):1149-1157.
doi: 10.1515/cclm-2019-1146
doi: 10.2337/diabetes.50.5.1149
187. Subramaniam S, Fletcher C. Trimethylamine N‐oxide:
177. Wang ZB, Xin SS, Ding LN, et al. The potential role of Breathe new life. Br J Pharmacol. 2018;175(8):1344-1353.
probiotics in controlling overweight/obesity and associated
metabolic parameters in adults: A systematic review doi: 10.1111/bph.13959
and meta-analysis. Evid Based Complement Altern Med. 188. Ufnal M, Zadlo A, Ostaszewski R. TMAO: A small molecule
2019;2019:3862971. of great expectations. Nutr Burbank Los Angel Cty Calif.
doi: 10.1155/2019/3862971 2015;31(11-12):1317-1323.
doi: 10.1016/j.nut.2015.05.006
178. Wu L, Ye S, Deng X, Fu Z, Li J, Yang C. Conjugated linoleic acid
ameliorates high fat-induced insulin resistance via regulating 189. Li J, Chen Z, Wang Q, et al. Microbial and metabolic profiles
gut microbiota-host metabolic and immunomodulatory unveil mutualistic microbe-microbe interaction in obesity-
interactions. Nutrients. 2024;16(8):1133. related colorectal cancer. Cell Rep Med. 2024;5(3):101429.
doi: 10.3390/nu16081133 doi: 10.1016/j.xcrm.2024.101429
179. Heianza Y, Zhou T, He H, et al. Changes in bile acid subtypes 190. Barrea L, Annunziata G, Muscogiuri G, et al.
and long-term successful weight-loss in response to weight-loss Trimethylamine-N-oxide (TMAO) as novel potential

Volume 9 Issue 2 (2025) 38 doi: 10.36922/ejmo.8318