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Volume 9 ǀ Issue 3 ǀ September 2025 ǀ Page 1 – 301 ǀ

Eurasian Journal of Medicine and Oncology

https://accscience.com/journal/EJMO

CONTENTS

EDITORIAL
1 From the Editor’s desk
Bernd Kaina

REVIEW ARTICLES
4 Liver fibrosis: Clinical assessment, pathogenesis, and anti-fibrotic therapy
Xin Liu, Chongmiao Yang, Yanyan Liu, Xiaowen Lin, Wei Su, Jian Sun, Xiaoguang Zhao
19 CXC chemokines as potential non-invasive biomarkers and therapeutic targets for non-
alcoholic fatty liver disease: A review
Zhihui Li, Zhiyun Chen
32 NOTCH3 signalling as a therapeutic nexus: Bridging cerebral small vessel disease and
breast cancer pathophysiology
Zaw Myo Hein, Nisha Shantakumari, Muhammad Danial Che Ramli, Usman Jaffer, Hafizah Abdul Hamid, Che Mohd Nasril
Che Mohd Nassir
52 Update on systemic lupus erythematosus: A review
Abdurahman Alloghbi, Yousef Al Obaisi, Hussain Alkhurayb, Amal M Shawabka, Fahad S. Alshehri
63 Dynamics of FLT3 mutations in acute myeloid leukemia: A systematic review and meta-
analysis of shifts between diagnosis and relapsed/refractory disease
Lais Teixeira, Camilla Correia, Alini Ponte, Diego Miranda, Felipe Feistauer, Marco Aurélio Salvino

ORIGINAL RESEARCH ARTICLES
75 Mapping breast cancer protein interaction networks as metric spaces: Insights into central
zones and drug discovery targets
Emad Fadhal
86 Development of a novel risk model for stratifying skin cutaneous melanoma patients based
on prognostic senescence-related genes
Yiting Feng, Lanlan Liu, Yunjin Xie, Mingzhu Yin
100 The association between Vitamin D and breast cancer: A two-sample Mendelian
randomization study
Yang Xiao, Mei Yin, Xingyi Song
110 Comparative efficacy and safety of Zercepac® plus pyrotinib versus Zercepac® plus
pertuzumab in combination with chemotherapy as neoadjuvant therapy for HER2-positive
breast cancer: A retrospective study
Hong Gao, Jiali Lei, Zhaohua Gui, Shengying Wang
122 Meta-analysis of the prognostic value of KRAS and TP53 mutations in cholangiocarcinoma
Benfeng Xu, Chuhan Zhang, Yibin Zhou, Jianan Jin
133 Influencing factors of chemotherapy-related cognitive impairment in patients with breast
cancer
Ying Zhang, Shuhan Wu, Yunmiao Ma, Shuyang Chang, Jianhui Li, Bo Tian, Nan Jiang, Liping Yang, Kenian Pan, Xulong
Zhu
147 Revisiting the role of the Pfannenstiel incision in early-stage endometrial cancer
Cem Yagmur Ozdemir, Hasan Eroğlu, Necat Cağatay Sezer, Nayif Çicekli, Derya Yeğin Aksu, Dağıstan Tolga Arioz
155 Psychotherapists’ perspectives on the quality of psychological services for cancer patients
in Riyadh: A predictive study
Yahya Khatatbeh
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