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Global Health Econ Sustain                               COVID-19 pandemic and quality of life of cancer patients



            and social distancing, which were later accompanied by   (iii) How did the COVID-19 pandemic impact the early
            strict lockdowns.                                     diagnosis of the disease?
              During the COVID-19 outbreak, individuals belonging   (iv)  Were there any differences in the quality of life of
            to vulnerable groups, especially those afflicted with various   patients with different forms of cancer during the
            forms of cancer, experienced heightened repercussions.   COVID-19 pandemic?
            Cancer is a complex group of diseases whose prognosis is   (v)  What influence did the pandemic have on patient care
                                                                  in developing countries?
            affected by both early diagnosis and treatment (Li Wang
            &Wang, 2021).With the outbreak of the pandemic, there   2. Method
            was a notable shift in the operational dynamics of health-
            care facilities, leading to delays in diagnosis and treatment.   In the present study, an extensive search was conducted
            In particular, due to the risk of cross-contamination from   in Greek and international scientific literature on various
            the virus and the heavy workload in hospitals, the majority   recognized electronic and printed sources. The following
            of surgeries were postponed, with only those deemed   criteria were applied to each electronic source: (i) the
            absolutely necessary being performed. Consequently, this   studies have been published in the last 2  years; (ii) free
            situation increased the risk of disease progression, resulting   access to the studies (free full text); and (iii) the writing
            in a decline in the survival rate of cancer patients (Li Wang   language must be English during the literature search in
            &Wang, 2021). In addition, to reduce the risk of COVID-19   the Greek electronic databases; the keywords “cancer,”
            transmission, patients were often unable to have companions   “COVID-19,” “quality of life,” and “developing countries”
            from their support network present, further exacerbating the   were used. In the English electronic databases, the
            already tense psychological state of cancer patients. In general,   keywords “cancer,” “COVID-19,” “quality of life,” and
            a decline in emotional functioning and general quality of   “developing countries” were entered using the BOOLEAN
            life was observed in cancer patients during the COVID-19   strategy, specifically by employing the “AND” operator.
            outbreak. The reduced emotional functioning and quality of   Due  to  the  subject  of  this  review,  there  was  no  specific
            life during the COVID-19 pandemic is concerning for the   target population in terms of age and sex; therefore, no
            entire population, especially cancer patients. Owing to the   relevant criteria were used. The international terms were
            severity of the disease, cancer patients may not have the   also consistent with those identified in the MeSH (Medical
            opportunity to improve their quality of life after the end of   Subject Headings) catalogs, which are accessible through
            the pandemic, which is a fact they are aware of, adding also   the National Library of Medicine’s website at <http://www.
            struggles to their mental health (Bartels et al., 2021). The   ncbi.nlm.nih.gov/mesh>. The specific search was carried
            outbreak of COVID-19 has further exacerbated the financial   out in the month of December 2022. The extraction of
            crisis, resulting in a situation where many cancer patients   the results of the systematic review was done using the
            were unable to afford their treatments.            PRISMA flow diagram.
              In developing countries, the difficulties in managing   The  topic  chosen  for  this  review  was  influenced  by
            oncology  patients during COVID-19  were  greater  due   the significant impact of COVID-19 on a global level,
            to insufficient financial resources and reduced medical   especially on individuals belonging to vulnerable groups.
                                                               One of the main vulnerable groups is cancer patients, who
            and nursing staff. Hence, it is evident that the protective   have a higher risk  of being  affected compared to other
            measures taken during the pandemic, although important   groups. During the initial review of the literature, it was
            for reducing the spread of the virus, had serious   observed that Greek literature lags behind foreign-language
            consequences, especially for the individuals who belonged   literature. Therefore, we investigated how the COVID-19
            to the vulnerable population.
                                                               pandemic  affected the  quality of  life  of cancer  patients.
              This  systematic  review  assessed  the  impact  of   During the literature search, it was decided to investigate
            COVID-19 pandemic on the quality of life of individuals   different forms of cancer separately and how the pandemic
            suffering  from  various  forms  of  cancer  at  a  physical-  affected the patients suffering from it. The stages followed
            psychological level and at the stage of their treatment   for the collection of the bibliography were: (i)  research
            during the outbreak. The following questions formed the   and collection of the bibliography; (ii) evaluation of the
            basis of the documentation on the impact of COVID-19   literature based on the inclusion criteria and search terms
            pandemic on individuals with different types of cancer:  (keywords); (iii) discarding irrelevant studies based on
            (i)  What impact did the COVID-19 pandemic have on   title and/or abstract; and (iv) reading relevant studies and
               the psychology of cancer patients?              gathering information in the initial literature review. Owing
            (ii)  How was cancer disease progression affected during   to the large volume of results, all studies with a non-topic
               the COVID-19 pandemic?                          title were discarded. Then, all abstracts of the studies with


            Volume 2 Issue 2 (2024)                         2                        https://doi.org/10.36922/ghes.2636
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