Page 49 - GPD-2-4
P. 49
Gene & Protein in Disease Cyanine and cancer therapy
122. Edison N, Zuri D, Maniv I, et al., 2012, The Iap-antagonist 21: 442–454.
arts initiates caspase activation upstream of cytochrome C https://doi.org/10.1016/j.celrep.2017.09.052
and Smac/Diablo. Cell Death Differ, 19: 356–368.
133. Wang X, Simpson ER, Brown KA, 2015, P53: Protection
https://doi.org/10.1038/cdd.2011.112 against tumor growth beyond effects on cell cycle and
123. Raffo AJ, Perlman H, Chen MW, et al.,1995, Overexpression apoptosis. Cancer Res, 75: 5001–5007.
of Bcl-2 protects prostate cancer cells from apoptosis in https://doi.org/10.1158/0008-5472.CAN-15-0563
vitro and confers resistance to androgen depletion in vivo.
Cancer Res, 55: 4438–4445. 134. Yu G, Luo H, Zhang N, et al., 2019, Loss of P53 sensitizes
cells to palmitic acid-induced apoptosis by reactive
124. Fulda S, Meyer E, Debatin KM, 2002, Inhibition of trail- oxygen species accumulation. Int J Mol Sci, 20: 6268.
induced apoptosis by Bcl-2 overexpression. Oncogene,
21: 2283–2294. https://doi.org/10.3390/ijms20246268
https://doi.org/10.1038/sj.onc.1205258 135. Vousden KH, 2000, P53: Death star. Cell, 103: 691–694.
125. Foreman KE, Wrone-Smith T, Boise LH, et al., 1996, https://doi.org/10.1016/s0092-8674(00)00171-9
Kaposi’s sarcoma tumor cells preferentially express Bcl-Xl. 136. Chi SW, 2014, Structural insights into the transcription-
Am J Pathol, 149: 795–803. independent apoptotic pathway of P53. BMB Rep,
126. Krajewska M, Moss SF, Krajewski S, et al., 1996, Elevated 47: 167–172.
expression of Bcl-X and reduced bak in primary colorectal https://doi.org/10.5483/BMBRep.2014.47.3.261
adenocarcinomas. Cancer Res, 56: 2422–2427.
137. Tomita Y, Marchenko N, Erster S, et al., 2006, WT
127. Han JY, Hong EK, Choi BG, et al., 2003, Death receptor P53, but not tumor-derived mutants, bind to Bcl2 via
5 and Bcl-2 protein expression as predictors of tumor the DNA binding domain and induce mitochondrial
response to gemcitabine and cisplatin in patients permeabilization. J Biol Chem, 281: 8600–8606.
with advanced non-small-cell lung cancer. Med Oncol https://doi.org/10.1074/jbc.M507611200
(Northwood, London, England), 20: 355–362.
138. Marchenko ND, Moll UM, 2014, Mitochondrial death
https://doi.org/10.1385/MO:20:4:355
functions of P53. Mol Cell Oncol, 1: e955995.
128. Erovic BM, Pelzmann M, Grasl M, et al., 2005, Mcl-1,
vascular endothelial growth factor-R2, and 14-3-3sigma https://doi.org/10.1080/23723548.2014.955995
expression might predict primary response against 139. Moll UM, Zaika A, 2001, Nuclear and mitochondrial
radiotherapy and chemotherapy in patients with locally apoptotic pathways of P53. FEBS Lett, 493: 65–69.
advanced squamous cell carcinomas of the head and neck. https://doi.org/10.1016/s0014-5793(01)02284-0
Clin Cancer Res, 11: 8632–8636.
140. Mihara M, Erster S, Zaika A, et al., 2003, P53 Has a direct
https://doi.org/10.1158/1078-0432.CCR-05-1170 apoptogenic role at the mitochondria. Mol Cell, 11: 577–
129. Williams J, Lucas PC, Griffith KA, et al., 2005, Expression 590.
of Bcl-Xl in ovarian carcinoma is associated with https://doi.org/10.1016/s1097-2765(03)00050-9
chemoresistance and recurrent disease. Gynecol Oncol,
96: 287–295. 141. Aubrey BJ, Kelly GL, Janic A, et al., 2018, How does P53
induce apoptosis and how does this relate to P53-mediated
https://doi.org/10.1016/j.ygyno.2004.10.026 tumour suppression? Cell Death Differ, 25: 104–113.
130. Michaud WA, Nichols AC, Mroz EA, et al., 2009, Bcl-2 https://doi.org/10.1038/cdd.2017.169
blocks cisplatin-induced apoptosis and predicts poor
outcome following chemoradiation treatment in advanced 142. Vogelstein B, Lane D, Levine AJ, 2000, Surfing the P53
oropharyngeal squamous cell carcinoma. Clin Cancer Res, network. Nature, 408: 307–310.
15: 1645–1654. https://doi.org/10.1038/35042675
https://doi.org/10.1158/1078-0432.CCR-08-2581 143. Donepudi M, Grütter MG, 2002, Structure and zymogen
131. Yang D, Chen MB, Wang LQ, et al., 2013, Bcl-2 expression activation of caspases. Biophys Chem, 101–102: 145–153.
predicts sensitivity to chemotherapy in breast cancer: https://doi.org/10.1016/s0301-4622(02)00151-5
A systematic review and meta-analysis. J Exp Clin Cancer
Res, 32: 105. 144. O’Connor L, Harris AW, Strasser A, 2000, Cd95 (Fas/Apo-
1) and P53 signal apoptosis independently in diverse cell
https://doi.org/10.1186/1756-9966-32-105 types. Cancer Res, 60: 1217–1220.
132. Edison N, Curtz Y, Paland N, et al., 2017, Degradation 145. Liu X, Yue P, Khuri FR, et al., 2004, P53 upregulates death
of Bcl-2 by Xiap and Arts promotes apoptosis. Cell Rep, receptor 4 expression through an intronic P53 binding
Volume 2 Issue 4 (2023) 18 https://doi.org/10.36922/gpd.2486

