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Gene & Protein in Disease A review of exosome-mediated treatments

Availability of data 12. Xiong M, Zhang Q, Hu W, et al. The novel mechanisms and
applications of exosomes in dermatology and cutaneous
Not applicable. medical aesthetics. Pharmacol Res. 2021;166:105490.
References doi: 10.1016/j.phrs.2021.105490

1. Park SJ, Shin SH, Kim KR, Seok J, Park KY. Exosomes as novel 13. Hu S, Li Z, Lutz H, et al. Dermal exosomes containing miR-
player in dermatologic field. Dermatol Ther. 2022;35(11):e15883. 218-5p promote hair regeneration by regulating β-catenin
signaling. Sci Adv. 2020;6(30):eaba1685.
doi: 10.1111/dth.15883
doi: 10.1126/sciadv.aba1685
2. Kwon HH, Yang SH, Lee J, et al. Combination treatment
with human adipose tissue stem cell-derived exosomes and 14. An Y, Lin S, Tan X, et al. Exosomes from adipose-derived
fractional CO laser for acne scars: A 12-week prospective, stem cells and application to skin wound healing. Cell Prolif.
2
double-blind, randomized, split-face study. Acta Derm 2021;54(3):e12993.
Venereol. 2020;100(18):adv00310. doi: 10.1111/cpr.12993
doi: 10.2340/00015555-3666 15. Gupta AK, Wang T, Rapaport JA. Systematic review
of exosome treatment in hair restoration: Preliminary
3. Zhou L, Wang H, Jing J, Yu L, Wu X, Lu Z. Regulation
of hair follicle development by exosomes derived from evidence, safety, and future directions. J Cosmet Dermatol.
dermal Papilla cells. Biochem Biophys Res Commun. 2023;22(9):2424-2433.
2018;500(2):325-332. doi: 10.1111/jocd.15869
doi: 10.1016/j.bbrc.2018.04.067 16. Li Y, Wang G, Wang Q, Zhang Y, Cui L, Huang X. Exosomes
secreted from adipose-derived stem cells are a potential
4. Ha DH, Kim HK, Lee J, et al. Mesenchymal stem/stromal
cell-derived exosomes for immunomodulatory therapeutics treatment agent for immune-mediated alopecia. J Immunol
and skin regeneration. Cells. 2020;9(5):1157. Res. 2022;2022:7471246.
doi: 10.3390/cells9051157 doi: 10.1155/2022/7471246
5. Wang T, Gao H, Wang D, et al. Stem cell-derived exosomes in 17. Hicok K, Vangsness T, Dordevic M. Exosome origins: Why
the treatment of melasma and its percutaneous penetration. the cell source matters. Stem Cell Regen Med. 2020;4:1-4.
Lasers Surg Med. 2023;55(2):178-189. doi: 10.33425/2639-9512.1040
doi: 10.1002/lsm.23628 18. De A, Chakraborty D, Agarwal I, Sarda A. Present and
future use of exosomes in dermatology. Indian J Dermatol.
6. Al Aboud AM, Zito PM. Alopecia. In: StatPearls. Treasure
Island, FL: StatPearls Publishing; 2024. 2024.
doi: 10.4103/ijd.ijd_491_23
7. Shimizu Y, Ntege EH, Sunami H, Inoue Y. Regenerative
medicine strategies for hair growth and regeneration: 19. Emer J. Platelet-Rich Plasma (PRP): Current applications in
A narrative review of literature. Regen Ther. 2022;21:527-539. dermatology. Skin Therapy Lett. 2019;24(5):1-6.
doi: 10.1016/j.reth.2022.10.005 20. Gupta AK, Renaud HJ, Rapaport JA. Platelet-rich plasma
and cell therapy: The new horizon in hair loss treatment.
8. Glass GE. Photobiomodulation: The clinical applications of
low-level light Therapy. Aesthet Surg J. 2021;41(6):723-738. Dermatol Clin. 2021;39(3):429-445.
doi: 10.1016/j.det.2021.04.001
doi: 10.1093/asj/sjab025
21. Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment
9. Wang C, Wang M, Xu T, et al. Engineering bioactive self-
healing antibacterial exosomes hydrogel for promoting options for androgenetic alopecia: Efficacy, side effects,
chronic diabetic wound healing and complete skin compliance, financial considerations, and ethics. J Cosmet
regeneration. Theranostics. 2019;9(1):65-76. Dermatol. 2021;20(12):3759-3781.
doi: 10.1111/jocd.14537
doi: 10.7150/thno.29766
22. Gupta AK, Renaud HJ, Halaas Y, Rapaport JA. Exosomes:
10. Hu S, Li Z, Cores J, et al. Needle-free injection of exosomes A new effective non-surgical therapy for androgenetic
derived from human dermal fibroblast spheroids ameliorates alopecia? Skinmed. 2020;18(2):96-100.
skin photoaging. ACS Nano. 2019;13(10):11273-11282.
23. Mondal J, Pillarisetti S, Junnuthula V, et al. Hybrid
doi: 10.1021/acsnano.9b04384
exosomes, exosome-like nanovesicles and engineered
11. Tzng E, Bayardo N, Yang PC. Current challenges surrounding exosomes for therapeutic applications. J Control Release.
exosome treatments. Extracell Vesicle. 2023;2:100023. 2023;353:1127-1149.
doi: 10.1016/j.vesic.2023.100023 doi: 10.1016/j.jconrel.2022.12.027

Volume 3 Issue 2 (2024) 12 doi: 10.36922/gpd.3230