Page 98 - GPD-3-2
P. 98
Gene & Protein in Disease A review of exosome-mediated treatments
the MMP-9 expression through the PI3K/AKT pathway. Lim SK. Topical application of mesenchymal stem cell
Arch Biochem Biophys. 2020;681:108259. exosomes alleviates the imiquimod induced psoriasis-like
doi: 10.1016/j.abb.2020.108259 inflammation. Int J Mol Sci. 2021;22(2):720.
doi: 10.3390/ijms22020720
45. Heo JS, Kim S, Yang CE, Choi Y, Song SY, Kim HO.
Human adipose mesenchymal stem cell-derived exosomes: 56. Gowda R, Robertson BM, Iyer S, Barry J, Dinavahi SS,
A key player in wound healing. Tissue Eng Regen Med. Robertson GP. The role of exosomes in metastasis and
2021;18(4):537-548. progression of melanoma. Cancer Treat Rev. 2020;85:101975.
doi: 10.1007/s13770-020-00316-x doi: 10.1016/j.ctrv.2020.101975
46. Joorabloo A, Liu T. Engineering exosome-based biomimetic 57. Shi C, Pei S, Ding Y, et al. Exosomes with overexpressed
nanovehicles for wound healing. J Control Release. miR 147a suppress angiogenesis and infammatory
2023;356:463-480. injury in an experimental model of atopic dermatitis. Sci
doi: 10.1016/j.jconrel.2023.03.013 Rep. 2023;13(1):8904.
47. Han X, Wu P, Li L, et al. Exosomes derived from autologous doi: 10.1038/s41598-023-34418-y
dermal fibroblasts promote diabetic cutaneous wound 58. Zhao Z, Zhang L, Ocansey DKW, Wang B, Mao F. The role
healing through the Akt/β-catenin pathway. Cell Cycle. of mesenchymal stem cell-derived exosome in epigenetic
2021;20(5-6):616-629. modifications in inflammatory diseases. Front Immunol.
doi: 10.1080/15384101.2021.1894813 2023;14:1166536.
48. Wang Y, Shen X, Song S, et al. Mesenchymal stem cell- doi: 10.3389/fimmu.2023.1166536
derived exosomes and skin photoaging: From basic research 59. Padmasekar M, Savai R, Seeger W, Pullamsetti SS. Exposomes
to practical application. Photodermatol Photoimmunol to exosomes: Exosomes as tools to study epigenetic adaptive
Photomed. 2023;39(6):556-566. mechanisms in high-altitude humans. Int J Environ Res
doi: 10.1111/phpp.12910 Public Health. 2021;18(16):8280.
49. Rippa AL, Kalabusheva EP, Vorotelyak EA. Regeneration of doi: 10.3390/ijerph18168280
dermis: Scarring and cells involved. Cells. 2019;8(6):607. 60. Al-Masawa ME, Alshawsh MA, Ng CY, et al. Efficacy
doi: 10.3390/cells8060607 and safety of small extracellular vesicle interventions
in wound healing and skin regeneration: A systematic
50. Guo JA, Yu PJ, Yang DQ, Chen W. The antisenescence effect review and meta-analysis of animal studies. Theranostics.
of exosomes from human adipose-derived stem cells on skin 2022;12(15):6455-6508.
fibroblasts. Biomed Res Int. 2022;2022:1034316.
doi: 10.7150/thno.73436
doi: 10.1155/2022/1034316
61. Maji S, Yan IK, Parasramka M, Mohankumar S, Matsuda A,
51. Lu L, Bai W, Wang M, et al. Novel roles of bovine milk- Patel T. In vitro toxicology studies of extracellular vesicles.
derived exosomes in skin antiaging. J Cosmet Dermatol. J Appl Toxicol. 2017;37(3):310-318.
2023;23:1374-1385.
doi: 10.1002/jat.3362
doi: 10.1111/jocd.16112
62. Gu Z, Yin Z, Song P, et al. Safety and biodistribution of
52. Zhang Y, Zouboulis CC, Xiao Z. Exosomes from adipose- exosomes derived from human induced pluripotent stem
derived stem cells activate sebocytes through the PI3K/ cells. Front Bioeng Biotechnol. 2022;10:949724.
AKT/SREBP-1 pathway to accelerate wound healing. Cell
Tissue Res. 2024;396:329-342. doi: 10.3389/fbioe.2022.949724
doi: 10.1007/s00441-024-03872-z 63. Nazari H, Alborzi F, Heirani-Tabasi A, et al. Evaluating
the safety and efficacy of mesenchymal stem cell-derived
53. Tienda-Vázquez MA, Hanel JM, Márquez-Arteaga EM, et exosomes for treatment of refractory perianal fistula in
al. Exosomes: A promising strategy for repair, regeneration IBD patients: Clinical trial phase I. Gastroenterol Rep (Oxf).
and treatment of skin disorders. Cells. 2023;12(12):1625. 2022;10:goac075.
doi: 10.3390/cells12121625
doi: 10.1093/gastro/goac075
54. Lo Cicero A, Delevoye C, Gilles-Marsens F, et al. 64. Yu M, Liu W, Li J, et al. Exosomes derived from atorvastatin-
Exosomes released by keratinocytes modulate melanocyte pretreated MSC accelerate diabetic wound repair by
pigmentation. Nat Commun. 2015;6:7506. enhancing angiogenesis via AKT/eNOS pathway. Stem Cell
doi: 10.1038/ncomms8506 Res Ther. 2020;11(1):350.
55. Zhang B, Lai RC, Sim WK, Choo ABH, Lane EB, doi: 10.1186/s13287-020-01824-2
Volume 3 Issue 2 (2024) 14 doi: 10.36922/gpd.3230

