Page 98 - GPD-3-2
P. 98

Gene & Protein in Disease                                          A review of exosome-mediated treatments



               the  MMP-9  expression  through  the PI3K/AKT  pathway.   Lim   SK. Topical application of mesenchymal stem cell
               Arch Biochem Biophys. 2020;681:108259.             exosomes alleviates the imiquimod induced psoriasis-like
               doi: 10.1016/j.abb.2020.108259                     inflammation. Int J Mol Sci. 2021;22(2):720.
                                                                  doi: 10.3390/ijms22020720
            45.  Heo JS, Kim S, Yang CE, Choi Y, Song SY, Kim HO.
               Human adipose mesenchymal stem cell-derived exosomes:   56.  Gowda R, Robertson BM, Iyer S, Barry J, Dinavahi SS,
               A  key player in wound healing.  Tissue Eng Regen Med.   Robertson GP. The role of exosomes in metastasis and
               2021;18(4):537-548.                                progression of melanoma. Cancer Treat Rev. 2020;85:101975.
               doi: 10.1007/s13770-020-00316-x                    doi: 10.1016/j.ctrv.2020.101975
            46.  Joorabloo A, Liu T. Engineering exosome-based biomimetic   57.  Shi C, Pei S, Ding Y,  et  al. Exosomes with overexpressed
               nanovehicles for wound healing.  J  Control Release.   miR 147a suppress angiogenesis and infammatory
               2023;356:463-480.                                  injury in an experimental model of atopic dermatitis.  Sci
               doi: 10.1016/j.jconrel.2023.03.013                 Rep. 2023;13(1):8904.
            47.  Han X, Wu P, Li L, et al. Exosomes derived from autologous      doi: 10.1038/s41598-023-34418-y
               dermal fibroblasts promote diabetic cutaneous wound   58.  Zhao Z, Zhang L, Ocansey DKW, Wang B, Mao F. The role
               healing  through the Akt/β-catenin pathway.  Cell Cycle.   of mesenchymal stem cell-derived exosome in epigenetic
               2021;20(5-6):616-629.                              modifications in inflammatory diseases.  Front Immunol.
               doi: 10.1080/15384101.2021.1894813                 2023;14:1166536.
            48.  Wang Y, Shen X, Song S,  et  al. Mesenchymal stem cell-     doi: 10.3389/fimmu.2023.1166536
               derived exosomes and skin photoaging: From basic research   59.  Padmasekar M, Savai R, Seeger W, Pullamsetti SS. Exposomes
               to  practical application.  Photodermatol Photoimmunol   to exosomes: Exosomes as tools to study epigenetic adaptive
               Photomed. 2023;39(6):556-566.                      mechanisms in high-altitude humans.  Int J  Environ  Res
               doi: 10.1111/phpp.12910                            Public Health. 2021;18(16):8280.
            49.  Rippa AL, Kalabusheva EP, Vorotelyak EA. Regeneration of      doi: 10.3390/ijerph18168280
               dermis: Scarring and cells involved. Cells. 2019;8(6):607.  60.  Al-Masawa ME, Alshawsh MA, Ng CY,  et  al. Efficacy
               doi: 10.3390/cells8060607                          and safety of small extracellular vesicle interventions
                                                                  in wound healing and skin regeneration: A  systematic
            50.  Guo JA, Yu PJ, Yang DQ, Chen W. The antisenescence effect   review and meta-analysis of animal studies.  Theranostics.
               of exosomes from human adipose-derived stem cells on skin   2022;12(15):6455-6508.
               fibroblasts. Biomed Res Int. 2022;2022:1034316.
                                                                  doi: 10.7150/thno.73436
               doi: 10.1155/2022/1034316
                                                               61.  Maji S, Yan IK, Parasramka M, Mohankumar S, Matsuda A,
            51.  Lu L, Bai W, Wang M,  et al. Novel roles of bovine milk-  Patel T. In vitro toxicology studies of extracellular vesicles.
               derived  exosomes in skin antiaging.  J  Cosmet Dermatol.   J Appl Toxicol. 2017;37(3):310-318.
               2023;23:1374-1385.
                                                                  doi: 10.1002/jat.3362
               doi: 10.1111/jocd.16112
                                                               62.  Gu Z, Yin Z, Song P,  et al. Safety and biodistribution of
            52.  Zhang Y, Zouboulis CC, Xiao Z. Exosomes from adipose-  exosomes derived from human induced pluripotent stem
               derived  stem  cells  activate  sebocytes  through  the  PI3K/  cells. Front Bioeng Biotechnol. 2022;10:949724.
               AKT/SREBP-1 pathway to accelerate wound healing.  Cell
               Tissue Res. 2024;396:329-342.                      doi: 10.3389/fbioe.2022.949724
               doi: 10.1007/s00441-024-03872-z                 63.  Nazari H, Alborzi F, Heirani-Tabasi A,  et  al. Evaluating
                                                                  the safety and efficacy of mesenchymal stem cell-derived
            53.  Tienda-Vázquez MA, Hanel JM, Márquez-Arteaga EM, et   exosomes for treatment of refractory perianal fistula in
               al. Exosomes: A promising strategy for repair, regeneration   IBD patients: Clinical trial phase I. Gastroenterol Rep (Oxf).
               and treatment of skin disorders. Cells. 2023;12(12):1625.  2022;10:goac075.
               doi: 10.3390/cells12121625
                                                                  doi: 10.1093/gastro/goac075
            54.  Lo Cicero A, Delevoye C, Gilles-Marsens F,  et al.   64.  Yu M, Liu W, Li J, et al. Exosomes derived from atorvastatin-
               Exosomes released by keratinocytes modulate melanocyte   pretreated MSC accelerate diabetic wound repair by
               pigmentation. Nat Commun. 2015;6:7506.             enhancing angiogenesis via AKT/eNOS pathway. Stem Cell
               doi: 10.1038/ncomms8506                            Res Ther. 2020;11(1):350.
            55.  Zhang  B,  Lai  RC,  Sim  WK,  Choo  ABH,  Lane  EB,      doi: 10.1186/s13287-020-01824-2


            Volume 3 Issue 2 (2024)                         14                              doi: 10.36922/gpd.3230
   93   94   95   96   97   98   99   100   101   102   103