Page 35 - GPD-3-3

Gene & Protein in Disease Modulating immune response in liver by curcumin

12. Robinson MW, Harmon C, O’Farrelly C. Liver immunology J Hepatol. 1995;22(2):226-269.
and its role in inflammation and homeostasis. Cell Mol doi: 10.1016/0168-8278(95)80433-1
Immunol. 2016;13(3):267-276.
25. Groux H, Bigler M, de Vries JE, Roncarolo MG.
doi: 10.1038/cmi.2016.3 Interleukin-10 induces a long-term antigen-specific anergic
13. Heymann F, Tacke F. Immunology in the liver--from state in human CD4+ T cells. J Exp Med. 1996;184(1):19-29.
homeostasis to disease. Nat Rev Gastroenterol Hepatol. doi: 10.1084/jem.184.1.19
2016;13(2):88-110.
26. Knolle PA, Uhrig A, Hegenbarth S, Löser E, Schmitt E,
doi: 10.1038/nrgastro.2015.200
Gerken G, Lohse AW. IL-10 down-regulates T cell activation
14. Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor by antigen-presenting liver sinusoidal endothelial cells
cells as regulators of the immune system. Nat Rev Immunol. through decreased antigen uptake via the mannose receptor
2009;9(3):162-174. and lowered surface expression of accessory molecules. Clin
Exp Immunol. 1998;114(3):427-433.
doi: 10.1038/nri2506
doi: 10.1046/j.1365-2249.1998.00713.x
15. Racanelli V, Rehermann B. The liver as an immunological
organ. Hepatology. 2006;43(2 Suppl 1):S54-S62. 27. Heymann F, Peusquens J, Ludwig-Portugall I, et al. Liver
inflammation abrogates immunological tolerance induced
doi: 10.1002/hep.21060
by Kupffer cells. Hepatology. 2015;62(1):279-291.
16. Tacke F, Luedde T, Trautwein C. Inflammatory pathways in doi: 10.1002/hep.27793
liver homeostasis and liver injury. Clin Rev Allergy Immunol.
2009;36:4-12. 28. De Creus A, Abe M, Lau AH, Hackstein H, Raimondi G,
Thomson AW. Low TLR4 expression by liver dendritic cells
doi: 10.1007/s12016-008-8091-0
correlates with reduced capacity to activate allogeneic T cells
17. Yki-Järvinen H, Luukkonen PK, Hodson L, Moore JB. in response to endotoxin. J Immunol. 2005;174(4):2037-2045.
Dietary carbohydrates and fats in nonalcoholic fatty liver doi: 10.4049/jimmunol.174.4.2037
disease. Nat Rev Gastroenterol Hepatol. 2021;18(11):770-786.
29. Bamboat ZM, Stableford JA, Plitas G, et al. Human
doi: 10.1038/s41575-021-00472-y
liver dendritic cells promote T cell hyporesponsiveness.
18. Tall AR, Yvan-Charvet L. Cholesterol, inflammation and J Immunol. 2009;182(4):1901-1911.
innate immunity. Nat Rev Immunol. 2015;15(2):104-116.
doi: 10.4049/jimmunol.0803404
doi: 10.1038/nri3793
30. Kingham TP, Chaudhry UI, Plitas G, Katz SC, Raab J,
19. Tannahill GM, Curtis AM, Adamik J, et al. Succinate is an DeMatteo RP. Murine liver plasmacytoid dendritic cells
inflammatory signal that induces IL-1β through HIF-1α. become potent immunostimulatory cells after Flt-3 ligand
Nature. 2013;496(7444):238-242. expansion. Hepatology. 2007;45(2):445-454.
doi: 10.1038/nature11986 doi: 10.1002/hep.21457
20. Protzer U, Maini MK, Knolle PA. Living in the liver: Hepatic 31. Tokita D, Sumpter TL, Raimondi G, et al. Poor allostimulatory
infections. Nat Rev Immunol. 2012;12(3):201-213. function of liver plasmacytoid DC is associated with pro-
apoptotic activity, dependent on regulatory T cells. J Hepatol.
doi: 10.1038/nri3169
2008;49(6):1008-1018.
21. Crispe IN. Immune tolerance in liver disease. Hepatology. doi: 10.1016/j.jhep.2008.07.028
2014;60(6):2109-2117.
32. Ichikawa S, Mucida D, Tyznik AJ, Kronenberg M,
doi: 10.1002/hep.27254
Cheroutre H. Hepatic stellate cells function as regulatory
22. Calne RY, Sells RA, Pena JR, et al. Induction of bystanders. J Immunol. 2011;186(10):5549-5555.
immunological tolerance by porcine liver allografts. Nature. doi: 10.4049/jimmunol.1003917
1969;223(5205):472-476.
33. Wuensch SA, Spahn J, Crispe IN. Direct, help-independent
doi: 10.1038/223472a0
priming of CD8+ T cells by adeno-associated virus-
23. Lerut J, Sanchez-Fueyo A. An appraisal of tolerance in liver transduced hepatocytes. Hepatology. 2010;52(3):1068-1077.
transplantation. Am J Transplant. 2006;6(8):1774-1780.
doi: 10.1002/hep.23745
doi: 10.1111/j.1600-6143.2006.01396.x
34. Bowen DG, Zen M, Holz L, Davis T, McCaughan GW,
24. Knolle P, Schlaak J, Uhrig A, Kempf P, Meyer zum Bertolino P. The site of primary T cell activation is a
Büschenfelde KH, Gerken G. Human Kupffer cells secrete determinant of the balance between intrahepatic tolerance
IL-10 in response to lipopolysaccharide (LPS) challenge. and immunity. J Clin Invest. 2004;114(5):701-712.

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