Page 74 - GTM-3-2

Global Translational Medicine Genes and blood cells in Ph-negative MPNs

Availability of data A novel oncogenic role for urokinase receptor in leukemia
cells: Molecular sponge for oncosuppressor microRNAs.
Data used in this work are available from the corresponding Oncotarget. 2018;9(45):27823-27834.
author upon reasonable request.
doi: 10.18632/oncotarget.25597
References 12. Santibanez JF. Urokinase type plasminogen activator and the
1. Coltro G, Loscocco GG, Vannucchi AM. Classical molecular mechanisms of its regulation in cancer. Protein
Philadelphia-negative myeloproliferative neoplasms Pept Lett. 2017;24(10):936-946.
(MPNs): A continuum of different disease entities. Int Rev doi: 10.2174/0929866524666170818161132
Cell Mol Biol. 2021;365:1-69.
13. Irmak-Yazicioglu MB, Ergun K. Role of plasminogen
doi: 10.1016/bs.ircmb.2021.09.001 activator inhibitor-1 (PAI-1) in cancer stem cells. WCRJ.
2. Arber DA, Orazi A, Hasserjian RP, et al. International 2022;9:e2252.
consensus classification of myeloid neoplasms and acute doi: 10.32113/wcrj_20223_2252
leukemias: Integrating morphologic, clinical, and genomic
data. Blood. 2022;140(11):1200-1228. 14. Kunz C, Pebler S, Otte J, von der Ahe D. Differential
regulation of plasminogen activator and inhibitor gene
doi: 10.1182/blood.2022015850 transcription by the tumor suppressor p53. Nucleic Acids
3. Rumi E, Cazzola M. Diagnosis, risk stratification, and Res. 1995;23(18):3710-3717.
response evaluation in classical myeloproliferative doi: 10.1093/nar/23.18.3710
neoplasms. Blood. 2017;129(6):680-692.
15. Jensen MK, Riisbro R, Holten-Andersen MN, et al. Collagen
doi: 10.1182/blood-2016-10-695957 metabolism and enzymes of the urokinase plasminogen
4. Vainchenker W, Kralovics R. Genetic basis and molecular activator system in chronic myeloproliferative disorders:
pathophysiology of classical myeloproliferative neoplasms. Correlation between plasma-soluble urokinase plasminogen
Blood. 2017;129(6):667-679. activator receptor and serum markers for collagen
metabolism. Eur J Haematol. 2003;71(4):276-282.
doi: 10.1182/blood-2016-10-695940
doi: 10.1034/j.1600-0609.2003.00134.x
5. Chachoua I, Pecquet C, El-Khoury M, et al. Thrombopoietin
receptor activation by myeloproliferative neoplasm associated 16. Westerhausen DR Jr., Hopkins WE, Billadello JJ. Multiple
calreticulin mutants. Blood. 2016;127(10):1325-1335. transforming growth factor-beta-inducible elements regulate
expression of the plasminogen activator inhibitor type-1
doi: 10.1182/blood-2015-11-681932 gene in Hep G2 cells. J Biol Chem. 1991;266(2):1092-1100.
6. Falanga A, Marchetti M. Thrombosis in myeloproliferative 17. Rabieian R, Boshtam M, Zareei M, Kouhpayeh S,
neoplasms. Semin Thromb Hemost. 2014;40(3):348-358. Masoudifar A, Mirzaei H. Plasminogen activator
doi: 10.1055/s-0034-1370794 inhibitor type-1 as a regulator of fibrosis. J Cell Biochem.
2018;119(1):17-27.
7. Chia YC, Siti Asmaa MJ, Ramli M, et al. Molecular genetics
of thrombotic myeloproliferative neoplasms: Implications in doi: 10.1002/jcb.26146
precision oncology. Diagnostics (Basel). 2023;13(1):163. 18. Teng F, Zhang JX, Chen Y, et al. LncRNA NKX2-1-AS1
doi: 10.3390/diagnostics13010163 promotes tumor progression and angiogenesis via
up-regulation of SERPINE1 expression and activation of the
8. Marin Oyarzún CP, Heller PG. Platelets as mediators VEGFR-2 signaling pathway in gastric cancer. Mol Oncol.
of thromboinflammation in chronic myeloproliferative 2021;15(4):1234-1255.
neoplasms. Front Immunol. 2019;10:1373.
doi: 10.1002/1878-0261.12911
doi: 10.3389/fimmu.2019.01373
19. Prabhudesai A, Shetty S, Ghosh K, Kulkarni B. Investigation of
9. Sender R, Fuchs S, Milo R. Revised estimates for the plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter
number of human and bacteria cells in the body. PLoS Biol. polymorphism in Indian venous thrombosis patients:
2016;14(8):e1002533.
A case-control study. Eur J Haematol. 2017;99(3):249-254.
doi: 10.1371/journal.pbio.1002533 doi: 10.1111/ejh.12912
10. Bianconi E, Piovesan A, Facchin F, et al. An estimation of 20. Zhang X, Cai X, Pan J. Correlation between PAI-1 gene
the number of cells in the human body. Ann Hum Biol. 4G/5G polymorphism and the risk of thrombosis in Ph
2013;40(6):463-471.
chromosome-negative myeloproliferative neoplasms. Clin
doi: 10.3109/03014460.2013.807878 Appl Thromb Hemost. 2020;26:1076029620935207.
11. Li Santi A, Gorrasi A, Alfieri M, Montuori N, Ragno P. doi: 10.1177/1076029620935207

Volume 3 Issue 2 (2024) 10 doi: 10.36922/gtm.2559