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International Journal of Bioprinting                      3D-printing silicone patient-specific soft-tissue expander














































            Figure 6. Patient-specific silicone expanders (right-sided mandibular defect): (a) X-ray image of the right-sided mandibular defect; (b) model of the defect
            part and its dimensions; (c) computer-aided design (CAD) model of the silicone expander; (d) the silicone expander fixed onto the acrylonitrile butadiene
            styrene (ABS) mandibular bone defect model.



            tensile testing, yielding a Young’s modulus of 310 MPa and   consideration  the  silicone  thickness  before  expansion)
            a Poisson’s ratio of 0.34. Boundary conditions were set with   after 6 weeks of immersion. This finding was used as the
            both soft tissue and silicone membrane bottom-fixed. The   mold parameter settings for subsequent expansion tests.
            silicone expansion displacement was set as 0.5 mm, which   Figure 7b illustrates the dimension changes during tablet
            was referenced as the size increase for the swellable tablet   expansion within the silicone membrane from weeks 1
            device in the length/width/height directions as reported   to 6. The tablets gradually swelled over time causing the
            from the swelling test performed in section 2.1. Fabrication   silicone membrane to enlarge to the intended volume size.
            of swellable tablets and volume expansion test.       In Figure 8, the relationship curve between the average
                                                               silicone expander slot expansion volume of five different
            3. Results                                         samples and the number of weeks indicated a fourth-

            The swelling test results for the swellable tablets after 24 h   degree polynomial curve; gradual growth in the first 2
            of immersion reported expansion dimensions of 28 mm   weeks, followed by continuous accelerated growth from
            in length, 14 mm in width, and approximately 5 mm in   the  second  to  the  fifth  week,  then  returning  to  gradual
            height. The overall expanded volume was 64 times the   growth tendencies from the fifth to sixth week.
            original  volume.  Figure  7a  depicts  swellable  tablets  at   The expansion tests for the comma- and heart-shaped
            compression, drying, and after immersion. Meanwhile,   silicone expanders indicated that the average volumes of
            the slot-shaped silicone expander achieved the anticipated   five different samples after 6 weeks were 5815 and 6392
            expansion volume of 1960 mm  (28 × 14 × 5 mm; where   mm , respectively. In comparison with the CAD models
                                     3
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            5 mm was the average height after expansion, taking into   for the comma- and heart-shaped expanders (i.e., with the
            Volume 10 Issue 4 (2024)                       572                                doi: 10.36922/ijb.2918
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