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International Journal of Bioprinting              Design and biomechanical analysis of porous tantalum prostheses





























             Figure 1. Illustration of the finite element models for (a) the prosthesis, (b) the tibia, (c) the assembly, and (d) the boundary and loading conditions.

            Young’s modulus and the yield strength decreased with the   for FEA simulation. According to the boundary conditions
            increasing pore size. The sample 300/1200 demonstrated   shown in Figure 1d, the von Mises stress and displacement
            the minimum Young’s modulus (1302.83 ± 76.96 MPa)   of the tantalum prosthesis and the tibia at a standing posture
            and yield strength (23.25 ± 0.06 MPa), whereas the sample   on single leg and on two legs were numerically simulated.
            600/900 saw the maximum Young’s modulus of 5719.32 ±   The maximum von Mises stress occurred at the contact
            100.61MPa and yield strength of 172.71 ± 1.67 MPa.  region between the prosthesis and the tibia (Figures  5a
                                                               and 6a), whereas the maximum displacement appeared on
            3.2. Construction of the tibia and prosthesis models  the upper surface of the prosthesis (Figures 5b and 6b).
            Figure 3a shows the constructed tibia model from the   For ease of  comparison, the maximum von Mises
            CT  data  of  the  patient.  An  obvious  bone  defect  was   stress and maximum displacement of various prostheses
            observed on the tibia adjacent to the artificial knee joint   and the corresponding values for the tibia were collected
            (arrow indicated). In order for implantation of a new total   and shown in Table 2 for single-leg standing posture and
            knee arthroplasty (TKA), a patient-specific prosthesis   in  Table 3 for two-leg standing posture. The maximum
            (Figure 3b) to the tibia defect (Figure 3c) was designed, and   strain of the tibia adjacent to the prosthesis was further
            its in vivo position in the tibia (Figure 3d) was simulated.   simulated. When standing on single leg (Table 2), the
            The obtained models were used for the following FEA   maximum von Mises stress varied from 24.56 MPa
            simulation in this work.                           (300/1200) to 26.87 MPa (600/900) for the prostheses and
                                                               from 53.65 MPa (600/900) to 69.64 MPa (300/1200) for the
            3.3. Finite element simulation                     tibia. All of the prostheses and tibia demonstrated small
            Four mesh sizes of the tibia were employed to compare   displacement of less than 0.15 mm. It is worth noting that
            the stress situation. The  number of the total meshes  in   the maximum strain of the tibia varied from 2682.5 με
            each model was Grid1 = 79,671, Grid2 = 81,422, Grid3 =   (600/900) to 3482.5 με (300/1200), and only those tibias
            105,145, and Grid4 = 128,701. Figure 4 shows the mesh   adjacent  to  the  prostheses  450/900,  600/1200,  600/1500,
            dependency based on the maximum von Mises stress of   and 600/900 demonstrated a maximum strain in the
            the tibia. The accessible error between the Grid3 and   range  of  400–3000  με.  Regarding  the  standing  posture
            the Grid4 model was 7.9%. Since Grid3 resulted in a less   with two legs (Table  3), the maximum von Mises stress
            computational time than Grid4, Grid3 was chosen as the   values of the prostheses and tibia were all smaller than
            source  mesh.  The  final  number of  meshes  was  105,145,   their corresponding values for single-leg standing posture.
            including 58,858 meshes for prosthesis (Figure 1a) and   The prostheses saw the maximum von Mises stress from
            46,287 meshes for patient’s tibia (Figure 1b).     12.28 MPa (prosthesis 300/1200) to 13.44 MPa (prosthesis
               Since the constructed prosthesis model geometrically   600/900) and the tibia saw the maximum von Mises
            matched well with the tibia (Figures 1c and 3d), a general   stress from 26.82 MPa (prosthesis 600/900) to 34.82 MPa
            analysis of static mechanics with binding contact was used   (prosthesis 300/1200). The maximum node displacements


            Volume 9 Issue 4 (2023)                        292                         https://doi.org/10.18063/ijb.735
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