Page 51 - v11i4

International Journal of Bioprinting 3D bioprinting of nerve guidance conduits

References 92 93 94 100 101 102 172 107 111 112 144 114

Confirming that the Engelbreth–Holm–Swarm hydrogel filling accelerates the repair of nerve Gelatin conduit as a physical microenvironment for axonal extension and the promotion of functional recovery after PNI Enhancement of conduit’s mechanical properties by adding a biocompatible GelMA/ The stent has a modulus of elasticity of approximately 22.36 MPa and is suitable for peripheral nerve tissue applications PLA support for axonal growth as a

Outcomes defects PEGDA hydrogel layer alternative to autografts doping in PCL and suturing to random orientation defects fibronectin/PEGDA

Resolution 0.1 mm – 1 mm 300 μm 0.1 mm 10 μm 10 μm 100 μm 0.1 mm 10 μm 0.1 mm 0.01 mm

Culture time 16 weeks 3 months 21 days 7 days 56 days 7 days 8 weeks 7 days 12 weeks 7 days – –

In vitro assessment of cell behavior 10 mm nerve defects in rats PC12 cell culture In vitro assessment of cell behavior 3 mm nerve defects In vitro assessment of cell behavior 10 mm nerve defects in rats In vitro assessment of cell behavior and neuronal differentiation 13 mm nerve defects in rats In vitro assessment of cell behavior and neuronal differentiation Abbreviations: 3D, three-dimensional; GelMA, gelatin met

Model in vitro in rats – –

In vitro/in vivo In vitro In vivo In vitro In vitro In vivo In vitro In vivo In vitro In vivo In vitro

Conduit structure Hollow Hollow Double-deck porous Hollow Microgroove Hollow Hollow Hollow – Hollow, porous, and micro-grooved Multi-channel lactic-co-glycolic acid; PNI, peripheral nerve injury; PPy, polypyrrole; SC, Schwann cell; SF, silk fibroin.

Method 3D printing Digital light processing Additive lathe 3D bioprinting Extrusion printing Extrusion printing Stereolithography Electrospinning Fused filament fabrication Electrospinning Electrospinning Stereolithography Stereolithography

Table 3. Continued... Materials GelMA/Engelbreth– Holm–Swarm GelMA/methoxy PEG- PCL GelMA/bone marrow stem cells/PEGDA Poly(lactic acid)/poly(ε- caprolactone)/graphene PLA PLA/PCL PCL/collagen nanofibers/graphene oxide PCL/decellularized extracellular matrix/ PDA Collagen I/PLGA Poly(l-lactic acid-co- ε-caprolactone/PLGA/ PPy Polyurethane/PEG- graphene oxide PEG

Volume 11 Issue 4 (2025) 43 doi: 10.36922/IJB025140120