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An International Journal of Optimization and Control: Theories & Applications
                                                  ISSN: 2146-0957 eISSN: 2146-5703
                                                   Vol.15, No.4, pp.750-778 (2025)
                                              https://doi.org/10.36922/IJOCTA025220106


            RESEARCH ARTICLE


            Data-driven optimization and parameter estimation for a metric
            graph epidemic model with applications to COVID-19 spread in
            Poland: A real-world example of optimization for a challenging
            Rosenbrock-type objective function


                                               †
                                                                  †
                            1*
                                               2
                                                                 1
            Hannah Kravitz , Christina Dur´on , Bryttani Nieves , and Moysey Brio   3 †
            1
             Fariborz Maseeh Department of Mathematics & Statistics, Portland State University, Portland,
            Oregon, United States of America
            2
             Natural Science Division, Pepperdine University, Malibu, California, United States of America
            3
             Department of Mathematics, University of Arizona, Tucson, Arizona, United States of America
             hkravitz@pdx.edu, christina.duron@pepperdine.edu, bryttani@pdx.edu, brio@arizona.edu
            ARTICLE INFO                     ABSTRACT
            Article History:                  In this paper, we apply data-driven optimization to estimate key parameters
            Received: May 29, 2025            in a metric graph-based epidemiological model, with the aim of analyzing the
            1st revised: August 13, 2025      effect of road networks on the geographic spread of epidemics. As a case study,
            2nd revised: August 28, 2025      we fit our model to data from the COVID-19 pandemic in Poland during 2021.
            3rd revised: September 7, 2025    Our dataset integrates county-level daily case reports, national census informa-
            Accepted: September 15, 2025      tion, and traffic flow studies. This framework allows us to examine the relative
            Published Online: October 14, 2025  contribution of specific travel routes over time and infer unobserved transmis-
                                              sion patterns in the presence of incomplete or unreliable case reporting. The
            Keywords:
            SIR model                         optimization problem that arises from the model fitting yields an objective
                                              function resembling the Rosenbrock “banana” or “valley” function, a classi-
            Rosenbrock function
                                              cal difficult benchmark for optimization algorithms. To our knowledge, this
            Metric graph
                                              represents the first appearance of a Rosenbrock-type function in a real-world
            Epidemiology
                                              epidemiological context. We demonstrate that such a structure can emerge
            Parameter estimation
                                              naturally from a simple uncoupled SIR model under specific conditions: a low
            AMS Classification 2010:          initial incidence rate and a prolonged infectious period. This suggests that the
            35Q92, 65K05, 90C51, 65Z05, 92B05  Rosenbrock behavior is an intrinsic feature of fitting compartmental models to
                                              approximately Gaussian epidemiological data, providing a realistic yet simple
                                              scenario with which to test optimization algorithms. We explore optimization
                                              strategies suited to the Rosenbrock-type structure and identify a feasible pa-
                                              rameter set for modeling the spread of COVID-19 in Poland. We use this set of
                                              parameters to identify discrepancies between the model and the data, explore
                                              how reducing traffic flow into urban areas can help flatten the infection curve,
                                              and identify some patterns in the distribution of intra- versus inter-city inci-
                                              dence rates. While recognizing the complex interplay of social and behavioral
                                              elements that cannot be fully captured in a high-level geographic model, our
                                              findings highlight the usefulness of metric graph-based models for understand-
                                              ing large-scale disease transmission in structured transportation networks.





            1. Introduction                                   the transmission of both waterborne and vector-
                                                              borne diseases; cholera can spread through con-
            Geographic transport networks play a fundamen-    taminated water, 1,2  while mosquitoes (vectors for
            tal role in the spread of epidemics. Fluvial sys-  diseases like malaria and dengue fever) frequently
                                                                               3,4
            tems, for example, have been shown to facilitate  breed near rivers.  Highways provide a similar
               *Corresponding Author
            †These authors contributed equally to this work.
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