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Innovative Medicines & Omics                                    Subdural hematoma associated with avapritinib



            Ethics approval and consent to participate         7.   Zhang H, Liu Q. Prognostic indicators for gastrointestinal
                                                                  stromal tumors: A review. Transl Oncol. 2020;13(10):100812.
            Patient gave consent to participate in this study.
                                                                  doi: 10.1016/j.tranon.2020.100812
            Consent for publication                            8.   Reiter A, Schwaab J, DeAngelo DJ, et al. Efficacy and safety

            Verbal consent has been obtained from the patient to   of Avapritinib in previously treated patients with advanced
            publish his data.                                     systemic mastocytosis. Blood Adv. 2022;6(21):5750-5762.
                                                                  doi: 10.1182/bloodadvances.2022007539
            Availability of data
                                                               9.   Joseph CP, Abaricia SN, Angelis MA,  et al. Optimal
            Not applicable.                                       avapritinib treatment strategies for patients with metastatic
                                                                  or unresectable gastrointestinal stromal tumors. Oncologist.
            References                                            2021;26(4):e622-e631.
            1.   Suresh Babu  MC, Chaudhuri  T, Babu KG,  et al. Metastatic      doi: 10.1002/onco.13632
               gastrointestinal stromal tumor: A  regional cancer center
               experience of 44 cases. South Asian J Cancer. 2017;6(3):118-121.  10.  George S, Jones RL, Bauer S,  et  al. Avapritinib in
                                                                  patients  with  advanced  gastrointestinal  stromal  tumors
               doi: 10.4103/sajc.sajc_290_16
                                                                  following at least three prior lines of therapy.  Oncologist.
            2.   Ahmed M. Recent advances in the management of    2021;26(4):e639-e649.
               gastrointestinal stromal tumor.  World J Clin Cases.
               2020;8(15):3142-3155.                              doi: 10.1002/onco.13674
                                                               11.  Li J, Zhang X, Deng Y, et al. Efficacy and safety of avapritinib
               doi: 10.12998/wjcc.v8.i15.3142
                                                                  in treating unresectable or metastatic gastrointestinal
            3.   Teuber A, Schulz T, Fletcher BS,  et al. Avapritinib-based   stromal tumors: A phase I/II, open-label, multicenter study.
               SAR studies unveil a binding pocket in KIT and PDGFRA.   Oncologist. 2023;28(2):187-e114.
               Nat Commun. 2024;15(1):63.
                                                                  doi: 10.1093/oncolo/oyac242
               doi: 10.1038/s41467-023-44376-8
                                                               12.  Gotlib J, Castells M, Elberink HO, et al. Avapritinib versus
            4.   Vallilas C, Sarantis P, Kyriazoglou A, et al. Gastrointestinal   placebo in indolent systemic mastocytosis.  NEJM Evid.
               stromal tumors (GISTs): Novel therapeutic strategies   2023;2(6):EVIDoa2200339.
               with immunotherapy and small molecules.  Int J Mol Sci.
               2021;22(2):493.                                    doi: 10.1056/EVIDoa2200339
               doi: 10.3390/ijms22020493                       13.  Hossain M, Habib I, Singha K, Kumar A. FDA-approved
                                                                  heterocyclic molecules for cancer treatment: Synthesis,
            5.   Cao L, Tian W, Zhao  Y,  et al. Gene mutations in
               gastrointestinal stromal tumors: Advances in treatment and   dosage, mechanism of action and their adverse effect.
               mechanism research. Glob Med Genet. 2024;11(4):251-262.  Heliyon. 2023;10(1):e23172.
               doi: 10.1055/s-0044-1789204                        doi: 10.1016/j.heliyon.2023.e23172
            6.   Jones RL, Serrano C, von Mehren M,  et al. Avapritinib   14.  Rong L, Xie M, Jiang M, Qiu H, Kong L. A post-marketing
               in unresectable or metastatic PDGFRA D842V-mutant   pharmacovigilance study of Avapritinib: Adverse event
               gastrointestinal stromal tumours: Long-term efficacy and   data mining and analysis based on the United States Food
               safety data from the NAVIGATOR phase I trial.  Eur J   and drug administration adverse event reporting system
               Cancer. 2021;145:132-142.                          database. Br J Clin Pharmacol. 2024;90(8):1816-1826.
               doi: 10.1016/j.ejca.2020.12.008                    doi: 10.1111/bcp.15673



















            Volume 2 Issue 1 (2025)                         97                               doi: 10.36922/imo.7068
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