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Innovative Medicines & Omics Economical method for titering viral vectors

Conflict of interest doi: 10.1128/JVI.72.11.8873-8883

The authors declare that they have no competing interests. 3. Kim VN, Mitrophanous K, Kingsman SM, Kingsman AJ.
Minimal requirement for a lentivirus vector based on human
Author contributions immunodeficiency virus type 1. J Virol. 1998;72(1):811-816.

Conceptualization: All authors doi: 10.1128/JVI.72.1.811-816
Formal analysis: Binhai Ren 4. Dull T, Zufferey, R, Kelly, et al. A third-generation lentivirus
Investigation: Binhai Ren vector with a conditional packaging system. J Virol.
Methodology, Binhai Ren, Najah T Nassif 1998;72(11):8463-84671.
Visualization: Ann M. Simpson doi: 10.1128/jvi.72.11.8463-8471
Writing – original draft: Binhai Ren
Writing – review & editing: All authors 5. Milone MC, O’Doherty U. Clinical use of lentiviral vectors.
Leukemia. 2018;32(7):1529-1541.
Ethics approval and consent to participate doi: 10.1038/s41375-018-0106-0
Not applicable. 6. Ding B, Kilpatrick DL. Lentiviral vector production,
titration, and transduction of primary neurons. Methods
Consent for publication Mol Biol. 2013;1018:119-131.
Not applicable. doi: 10.1007/978-1-62703-444-9_12

Availability of data 7. Grigorov B, Rabilloud J, Lawrence P, et al. Rapid titration of
measles and other viruses: Optimization with determination
Data can be obtained from the corresponding author. of replication cycle length. PloS One. 2011;6(9):e24135.

References doi: 10.1371/journal.pone.0024135
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J Virol. 1998;72(11):8873-8883. doi: 10.1007/s12033-014-9815-4

Volume 2 Issue 1 (2025) 92 doi: 10.36922/imo.6552