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INNOSC Theranostics and
Pharmacological Sciences From fever to seizure: A pediatric case study

meningeal signs, and abnormal neurological findings. This Acknowledgments
adds a practical dimension to identifying high-risk cases. 24
None.
3.5. Management Funding

While both sources touch upon the management of febrile
seizures, the second source provides additional insights None.
into the psychological impact on families and emphasizes Conflict of interest
the importance of reassurance and education. It also details
the acute phase treatment, including considerations for The authors declare that they have no conflict of interest.
prolonged seizures and when to seek medical assistance.
25
The comparison highlights variations in recommendations Author contributions
and perspectives in the evaluation and management of Conceptualization: All authors
febrile seizures. While both sources provide valuable Investigation: All authors
insights, the nuanced approach presented in the second Methodology: All authors
source, along with specific considerations and red flags, Writing – original draft: All authors
offers a more comprehensive guide for clinicians dealing Writing – review & editing: All authors
with this common childhood condition. These differences
underscore the evolving nature of clinical guidelines and Ethics approval and consent to participate
the need for a case-specific, patient-centered approach in Not applicable.
managing febrile seizures in children.

4. Conclusion Consent for publication
A written informed consent was obtained from the patient.
This case report of FSE in a pediatric patient illuminates
the intricate landscape and challenges associated Availability of data
with managing critical conditions in children. The
multidimensional aspects of diagnosis and treatment, Not applicable.
as detailed in the report, underscore the indispensable References
role of clinical pharmacists in optimizing medication
strategies. The achievement of a 48-h afebrile state signifies 1. Leung AK, Hon KL, Leung TN. Febrile seizures: An
the effectiveness of the optimized treatment protocol overview. Drugs Context. 2018;7:212536.
implemented. Notably, the report emphasizes the pivotal doi: 10.7573/dic.212536
contribution of clinical pharmacists, showcasing their
expertise in medication review, dosage adjustment, drug 2. Batra P, Thakur N, Mahajan P, et al. An evidence-based
approach to evaluation and management of the febrile
interaction assessment, and patient counseling. The child in Indian emergency department. Int J Crit Illn Inj Sci.
collaborative health-care approach involving pediatricians, 2018;8(2):63-72.
neurologists, and clinical pharmacists proves essential in
navigating the complexities of pediatric febrile seizures doi: 10.4103/IJCIIS.IJCIIS_3_18
progressing to status epilepticus (SE). The rationale 3. Pavone P, Corsello G, Ruggieri M, Marino S, Marino S,
behind the choice of anti-seizure medications, specifically Falsaperla R. Benign and severe early-life seizures: A round
levetiracetam and clobazam, is elucidated, with evidence- in the first year of life. Ital J Pediatr. 2018;44(1):54.
based support. The dynamic nature of the patient’s doi: 10.1186/s13052-018-0491-z
symptoms underscores the necessity for close monitoring 4. Auvin S, Antonios M, Benoist G, et al. Évaluation d’un
and adaptive medication adjustments. Furthermore, the enfant après une crise fébrile: Focus sur trois problèmes
recommendation for a follow-up in the pediatric outpatient de pratique clinique [Evaluating a child after a febrile
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points convey the profound significance of collaborative
healthcare, the vital role of clinical pharmacists, evidence- 5. Kwon A, Kwak BO, Kim K, et al. Cytokine levels in febrile
based decision-making, and the nuanced complexities seizure patients: A systematic review and meta-analysis.
involved in managing pediatric febrile seizures evolving Seizure. 2018;59:5-10.
into SE. doi: 10.1016/j.seizure.2018.04.023

Volume 7 Issue 2 (2024) 5 doi: 10.36922/itps.2735