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Volume 8 ǀ Issue 2 ǀ April 2025 ǀ Page 1 – 107 ǀ

                                                  INNOSC Theranostics and Pharmacological Sciences

                                                                             https://accscience.com/journal/ITPS


           CONTENTS





            REVIEW ARTICLES
            1       The role of AMPK activation in metabolic regulation, energy homeostasis and aging: A
                    comprehensive overview
                    George Jîtcă
            16      Current view on photodynamic therapy in medicine
                    David Aebisher, Julia Tomaszewska, Emilia Tomaka, Dorota Bartusik-Aebisher
            31      Emerging biomarkers in major depressive disorder: Diagnostic, prognostic, and therapeutic
                    implications
                    Muhammad Kamran Ameer, Muhammad Ikram, Muhammad Imran Khan, Fazal Wahab, Muhammad Imran Naseer, Najeeb
                    Ullah
            46      Vericiguat for heart failure with reduced ejection fraction (HFrEF): A review of its potential
                    benefits in Pakistan
                    Maria Qadri, Komal Zulfiqar, Daniah Rizwan, Sulafa Rasheed Ahmed Ali, Malik Olatunde Oduoye, Ummsalamah Adenike
                    Musa, Ahmad Sameed Akram, Awais Habib, Atif Hussain Sarwar, Chinazom Judith Ejim


            ORIGINAL RESEARCH ARTICLES
            55      Preclinical evaluation reveals comparable toxicology and pharmacology of the
                    erythropoietin biosimilar GBpoietin® and Eprex®
                    Kakon Nag, Mohammad Mohiuddin, Md. Maksudur Rahman Khan, Samir Kumar, Md. Enamul Haq Sarker, Bipul Kumar
                    Biswas, Sheikh Rejaul Haq, Sitesh Chandra Bachar, Naznin Sultana
            68      Repeated ketamine doses elevate superoxide dismutase activity in a pharmacological model
                    of schizophrenia-like phenotypes in mice
                    Yusuf Usman, Adegbuyi Oladele Aderibigbe, Fatai Adewale Fehintola
            77      Antioxidant effects of curcumin in unilateral spinal cord injury model in adult male rats
                    Babak Ebrahimi, Atousa Yarahmadi, Neda Ghaffari, Gholamreza Hassanzadeh


            MINI-REVIEW
            87      Transformative natural product-drug combinations: Advancing techniques to enhance
                    efficacy against drug-resistant pathogens
                    Mathew Gideon


            CASE SERIES
            96      Evaluation of galactomannan and 1,3-β-d-glucan assays as diagnostic tools for intracranial
                    fungal infection: A case series
                    Suneel Kumar, Zuhaa Rehman, Anabia Akhlaq, Taha Bin Ajaz Khan, Naeemullah Bullo, Munir Afzal


            CASE REPORT
            102     Drug-induced hypoglycemia in a patient with Type 2 diabetes and renal impairment: A case
                    report
                    Sara Shreen, Mir Wajahath Ali, Mohammed Arshad Khan, Sulaiman Abdul Majeed, Mohammed Misbah Ul Haq



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