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Volume 8 ǀ Issue 2 ǀ April 2025 ǀ Page 1 – 107 ǀ
INNOSC Theranostics and Pharmacological Sciences
https://accscience.com/journal/ITPS
CONTENTS
REVIEW ARTICLES
1 The role of AMPK activation in metabolic regulation, energy homeostasis and aging: A
comprehensive overview
George Jîtcă
16 Current view on photodynamic therapy in medicine
David Aebisher, Julia Tomaszewska, Emilia Tomaka, Dorota Bartusik-Aebisher
31 Emerging biomarkers in major depressive disorder: Diagnostic, prognostic, and therapeutic
implications
Muhammad Kamran Ameer, Muhammad Ikram, Muhammad Imran Khan, Fazal Wahab, Muhammad Imran Naseer, Najeeb
Ullah
46 Vericiguat for heart failure with reduced ejection fraction (HFrEF): A review of its potential
benefits in Pakistan
Maria Qadri, Komal Zulfiqar, Daniah Rizwan, Sulafa Rasheed Ahmed Ali, Malik Olatunde Oduoye, Ummsalamah Adenike
Musa, Ahmad Sameed Akram, Awais Habib, Atif Hussain Sarwar, Chinazom Judith Ejim
ORIGINAL RESEARCH ARTICLES
55 Preclinical evaluation reveals comparable toxicology and pharmacology of the
erythropoietin biosimilar GBpoietin® and Eprex®
Kakon Nag, Mohammad Mohiuddin, Md. Maksudur Rahman Khan, Samir Kumar, Md. Enamul Haq Sarker, Bipul Kumar
Biswas, Sheikh Rejaul Haq, Sitesh Chandra Bachar, Naznin Sultana
68 Repeated ketamine doses elevate superoxide dismutase activity in a pharmacological model
of schizophrenia-like phenotypes in mice
Yusuf Usman, Adegbuyi Oladele Aderibigbe, Fatai Adewale Fehintola
77 Antioxidant effects of curcumin in unilateral spinal cord injury model in adult male rats
Babak Ebrahimi, Atousa Yarahmadi, Neda Ghaffari, Gholamreza Hassanzadeh
MINI-REVIEW
87 Transformative natural product-drug combinations: Advancing techniques to enhance
efficacy against drug-resistant pathogens
Mathew Gideon
CASE SERIES
96 Evaluation of galactomannan and 1,3-β-d-glucan assays as diagnostic tools for intracranial
fungal infection: A case series
Suneel Kumar, Zuhaa Rehman, Anabia Akhlaq, Taha Bin Ajaz Khan, Naeemullah Bullo, Munir Afzal
CASE REPORT
102 Drug-induced hypoglycemia in a patient with Type 2 diabetes and renal impairment: A case
report
Sara Shreen, Mir Wajahath Ali, Mohammed Arshad Khan, Sulaiman Abdul Majeed, Mohammed Misbah Ul Haq
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