Page 62 - ITPS-8-3
P. 62

INNOSC Theranostics and
            Pharmacological Sciences                                           Precision medicine and beyond in oncology



               colorectal cancer: Pioneering new avenues in solid tumor   hereditary breast cancer: American society of clinical
               immunotherapy. J Clin Oncol. 2025;43(8):994-1005.  oncology, American Society for radiation oncology,
               doi: 10.1200/jco-24-02081                          and society of surgical oncology guideline.  J  Clin Oncol.
                                                                  2020;38(18):2080-2106.
            101. Zhu Y, Zuo D, Wang K, et al. Mesothelin-targeted CAR-T
               therapy combined with irinotecan for the treatment of solid      doi: 10.1200/jco.20.00299
               cancer. J Cancer Res Clin Oncol. 2023;149(16):15027-15038.  112. Wang J, Zhang Y, Yuan L, Ren L, Zhang Y, Qi X.
               doi: 10.1007/s00432-023-05279-9                    Comparative efficacy, safety, and acceptability of single-
                                                                  agent poly (ADP-ribose) polymerase (PARP) inhibitors
            102. Buscail L, Bournet B, Cordelier P. Role of oncogenic KRAS   in BRCA-mutated HER2-negative metastatic or advanced
               in  the  diagnosis,  prognosis  and  treatment  of  pancreatic   breast cancer: A network meta-analysis. Aging (Albany NY).
               cancer. Nat Rev Gastroenterol Hepatol. 2020;17(3):153-168.  2020;13(1):450-459.
               doi: 10.1038/s41575-019-0245-4                     doi: 10.18632/aging.202152
            103. Tew BY, Durand JK, Bryant KL,  et  al. Genome-wide   113. Lu X, Deng S, Xu J,  et al. Combination of AFP vaccine
               DNA methylation analysis of KRAS mutant cell lines. Sci   and immune checkpoint inhibitors slows hepatocellular
               Rep. 2020;10(1):10149.                             carcinoma progression in preclinical models. J Clin Invest.
               doi: 10.1038/s41598-020-66797-x                    2023;133(11):e163291.
            104. Strickler JH, Satake H, George TJ, et al. Sotorasib in KRAS      doi: 10.1172/jci163291
               p.G12C-mutated advanced pancreatic cancer. N Engl J Med.   114. Zhong L, Gan L, Wang B,  et al. Hyperacute rejection-
               2023;388(1):33-43.
                                                                  engineered oncolytic virus for interventional clinical trial in
               doi: 10.1056/NEJMoa2208470                         refractory cancer patients. Cell. 2025;188(4):1119-1136.e23.
            105. Cilliers C, Howgate E, Jones  HM, Rahbaek L, Tran JQ.      doi: 10.1016/j.cell.2024.12.010
               Clinical and physiologically based pharmacokinetic model
               evaluations of adagrasib drug-drug interactions.  Clin   115. Aggeletopoulou I, Pantzios S, Triantos C. Personalized
                                                                  immunity: Neoantigen-based vaccines revolutionizing
               Pharmacol Ther. 2025;117(3):732-741.
                                                                  hepatocellular carcinoma treatment.  Cancers (Basel).
               doi: 10.1002/cpt.3506                              2025;17(3):376.
            106. Peng TR, Wu TW, Yi TY, Wu AJ. Comparative efficacy of      doi: 10.3390/cancers17030376
               adagrasib and sotorasib in KRAS G12C-mutant NSCLC:
               Insights from pivotal trials. Cancers. 2024;16(21):3676.  116. Xu Z, Ji G, Cui Y, Cui X. The impacts of non-coding RNAs
                                                                  and N(6)-methyladenosine on cancer: Past, present and
            107. Kaufman B, Shapira-Frommer R, Schmutzler RK,  et   future. Curr Cancer Drug Targets. 2021;21(5):375-385.
               al. Olaparib monotherapy in patients with advanced
               cancer and a germline BRCA1/2 mutation. J Clin Oncol.      doi: 10.2174/1568009621999210120193636
               2015;33(3):244-250.                             117. Liu  W,  Gao  X,  Chen  X,  et al.  miR-139-5p  loss-mediated
               doi: 10.1200/jco.2014.56.2728                      WTAP activation contributes to hepatocellular carcinoma
                                                                  progression by  promoting  the epithelial  to mesenchymal
            108. Javle M, Shacham-Shmueli E, Xiao L,  et al. Olaparib   transition. Front Oncol. 2021;11:611544.
               monotherapy for previously treated pancreatic cancer with
               DNA damage repair genetic alterations other than germline      doi: 10.3389/fonc.2021.611544
               BRCA variants: Findings from 2 phase 2 nonrandomized   118. Ma JZ, Yang F, Zhou CC,  et al. METTL14 suppresses
               clinical trials. JAMA Oncol. 2021;7(5):693-699.    the metastatic potential of hepatocellular carcinoma by
               doi: 10.1001/jamaoncol.2021.0006                   modulating  N6‐methyladenosine‐dependent  primary
                                                                  MicroRNA processing. Hepatology. 2017;65(2):529-543.
            109. Litton JK, Rugo HS, Ettl J, et al. Talazoparib in patients with
               advanced  breast  cancer  and  a  germline  BRCA  mutation.      doi: 10.1002/hep.28885
               N Engl J Med. 2018;379(8):753-763.              119. Wei J, Fang DL, Zhou W, He YF. N6-methyladenosine (m6A)
               doi: 10.1056/NEJMoa1802905                         regulatory gene divides hepatocellular carcinoma into three
                                                                  subtypes. J Gastrointest Oncol. 2021;12(4):1860-1872.
            110. Bruin MAC, Sonke GS, Beijnen JH, Huitema  ADR.
               Pharmacokinetics  and   pharmacodynamics  of       doi: 10.21037/jgo-21-378
               PARP inhibitors in oncology.  Clin Pharmacokinet.   120. Yankova E, Blackaby W, Albertella M, et al. Small-molecule
               2022;61(12):1649-1675.                             inhibition of METTL3 as a strategy against myeloid
               doi: 10.1007/s40262-022-01167-6                    leukaemia. Nature. 2021;593(7860):597-601.
            111. Tung NM, Boughey JC, Pierce LJ,  et  al. Management of      doi: 10.1038/s41586-021-03536-w


            Volume 8 Issue 3 (2025)                         56                          doi: 10.36922/ITPS025140018
   57   58   59   60   61   62   63   64   65   66   67