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INNOSC Theranostics and
Pharmacological Sciences Precision medicine and beyond in oncology

121. Zhang ZW, Teng X, Zhao F, et al. METTL3 regulates m(6)A data technologies, applications, and challenges for precision
methylation of PTCH1 and GLI2 in Sonic hedgehog signaling medicine: A review. Glob Chall. 2024;8(1):2300163
to promote tumor progression in SHH-medulloblastoma. doi: 10.1002/gch2.202300163
Cell Rep. 2022;41(4):111530.
132. Shmatko A, Ghaffari Laleh N, Gerstung M, Kather JN.
doi: 10.1016/j.celrep.2022.111530
Artificial intelligence in histopathology: Enhancing cancer
122. Haigh DB, Woodcock CL, Lothion-Roy J, et al. The METTL3 research and clinical oncology. Nat Cancer. 2022;3(9):1026-
RNA methyltransferase regulates transcriptional networks 1038.
in prostate cancer. Cancers (Basel). 2022;14(20):5148.
doi: 10.1038/s43018-022-00436-4
doi: 10.3390/cancers14205148
133. Tizhoosh HR, Diamandis P, Campbell CJV, et al. Searching
123. Xu QC, Tien YC, Shi YH, et al. METTL3 promotes images for consensus: Can AI remove observer variability in
intrahepatic cholangiocarcinoma progression by regulating pathology? Am J Pathol. 2021;191(10):1702-1708.
IFIT2 expression in an m(6)A-YTHDF2-dependent manner. doi: 10.1016/j.ajpath.2021.01.015
Oncogene. 2022;41(11):1622-1633.
134. van der Slot MA, Hollemans E, den Bakker MA, et al. Inter-
doi: 10.1038/s41388-022-02185-1
observer variability of cribriform architecture and percent
124. Wang L, Yang Q, Zhou Q, et al. METTL3-m(6)A-EGFR-axis Gleason pattern 4 in prostate cancer: Relation to clinical
drives lenvatinib resistance in hepatocellular carcinoma. outcome. Virchows Arch. 2021;478(2):249-256.
Cancer Lett. 2023;559:216122.
doi: 10.1007/s00428-020-02902-9
doi: 10.1016/j.canlet.2023.216122
135. Geller BM, Nelson HD, Carney PA, et al. Second opinion
125. Wang Z, Song S, Zhang L, Yang T, Yao W, Liang B. Hepatic in breast pathology: Policy, practice and perception. J Clin
arterial infusion chemotherapy combined with immune Pathol. 2014;67(11):955-960.
checkpoint inhibitors and molecular targeted therapies for doi: 10.1136/jclinpath-2014-202290
advanced infiltrative hepatocellular carcinoma: A single-
center experience. Front Immunol. 2024;15:1474442. 136. Ko YS, Choi YM, Kim M, et al. Improving quality control
in the routine practice for histopathological interpretation
doi: 10.3389/fimmu.2024.1474442
of gastrointestinal endoscopic biopsies using artificial
126. Rezvantalab S, Drude NI, Moraveji MK, et al. PLGA- intelligence. PLoS One. 2022;17(12):e0278542.
based nanoparticles in cancer treatment. Front Pharmacol. doi: 10.1371/journal.pone.0278542
2018;9:1260.
137. Wulczyn E, Steiner DF, Xu Z, et al. Deep learning-based
doi: 10.3389/fphar.2018.01260
survival prediction for multiple cancer types using
127. Bao Y, Zhai J, Chen H, et al. Targeting m(6)A reader YTHDF1 histopathology images. PLoS One. 2020;15(6):e0233678.
augments antitumour immunity and boosts anti-PD-1 doi: 10.1371/journal.pone.0233678
efficacy in colorectal cancer. Gut. 2023;72(8):1497-1509.
138. Dong T, Wang L, Li R, et al. Development of a novel deep
doi: 10.1136/gutjnl-2022-328845
learning-based prediction model for the prognosis of
128. Xiao Z, Li T, Zheng X, et al. Nanodrug enhances post-ablation operable cervical cancer. Computat Math Methods Med.
immunotherapy of hepatocellular carcinoma via promoting 2022;2022(1):4364663.
dendritic cell maturation and antigen presentation. Bioact doi: 10.1155/2022/4364663
Mater. 2023;21:57-68.
139. Yang L, Fan X, Qin W, et al. A novel deep learning prognostic
doi: 10.1016/j.bioactmat.2022.07.027
system improves survival predictions for stage III non-small
129. Hasan N, Aftab M, Ullah M, et al. Nanoparticle-based drug cell lung cancer. Cancer Med. 2022;11(22):4246-4255.
delivery system for oral cancer: Mechanism, challenges, and doi: 10.1002/cam4.4782
therapeutic potential. Results Chem. 2025;14:102068.
140. McGenity C, Clarke EL, Jennings C, et al. Artificial
doi: 10.1016/j.rechem.2025.102068
intelligence in digital pathology: A systematic review and
130. Locatelli F, Zugmaier G, Rizzari C, et al. Effect of meta-analysis of diagnostic test accuracy. NPJ Digit Med.
blinatumomab vs chemotherapy on event-free survival 2024;7(1):114.
among children with high-risk first-relapse B-cell acute doi: 10.1038/s41746-024-01106-8
lymphoblastic leukemia: A randomized clinical trial. JAMA.
2021;325(9):843-854. 141. Eisemann N, Bunk S, Mukama T, et al. Nationwide real-
world implementation of AI for cancer detection in
doi: 10.1001/jama.2021.0987
population-based mammography screening. Nat Med.
131. Yang X, Huang K, Yang D, Zhao W, Zhou X. Biomedical big 2025;31(3):917-924.

Volume 8 Issue 3 (2025) 57 doi: 10.36922/ITPS025140018