Page 40 - JCBP-1-1

Journal of Clinical and
Basic Psychosomatics Quality of life in patients with atopic dermatitis

Table 3. Analysis of factors influencing anxiety
Projects HADS‑A Fisher’s exact test Logistic regression analysis
No or suspected Abnormal Chi‑square value P‑value Wald P‑value OR (95%CI)
anxiety (%) anxiety (%)
Gender
Male 26 (26.8) 4 (44.4) 0.268 1.316 0.246 -
Female 71 (73.2) 5 (55.6)
Age
25 and below 30 (30.9) 1 (11.1) 1.905 0.648 1.685 0.64 -
26 – 35 years old 33 (34.0) 4 (44.4)
36 – 45 years old 16 (16.5) 2 (22.2)
46 years old and above 18 (18.6) 2 (22.2)
Education level
Middle school and below 18 (18.6) 3 (33.3) 1.286 0.589 1.556 0.459 -
University 64 (66.0) 5 (55.6)
Graduate student and above 15 (15.5) 1 (11.1)
Employment status
Unemployed 41 (42.3) 4 (44.4) 1 0.145 0.704 -
Employed 56 (57.7) 5 (55.6)
Working environment
Indoor 71 (73.2) 7 (77.8) 2.298 0.362 2.496 0.287 -
Outdoor 3 (3.1) 1 (11.1)
Both 23 (23.7) 1 (11.1)
Work nature
Light 15 (15.5) 2 (22.2) 0.948 0.832 0.07 0.995 -
Intellectual 58 (59.8) 5 (55.6)
Manual 7 (7.2) 0 (0.0)
Heavy 17 (17.5) 2 (22.2)
Atopic comorbidities
None 75 (77.3) 5 (55.6) 2.107 0.218 1.978 0.16 -
Exist 22 (22.7) 4 (44.4)
DLQI 7.0 (3.0 – 10.0) 14 (11.5 – 23.5) −3.608 <0.01 -
HADS-A 4.0 (2.0 – 6.0) 12.0 (11.0 – 15.0) −4.971 <0.01 -
Note: The logistic regression equation did not include variables with P>0.05, so there was no odds ratio (OR) value for this variable, and DLQI and
HADS-A were not subjected to multivariate analysis.
Abbreviations: DLQI: Dermatology life quality index; HADS-A: Hospital anxiety and depression scale anxiety; HADS-D: Hospital anxiety and
depression scale depression.
were significant predictors for anxiety, especially for AD There is no uniformity regarding the factors influencing
patients between 41 and 60 years old. Severe skin pain and the mean HADS-A and HADS-D scores in patients with AD.
hospitalization in the past year were reported as significant There are multiple previous case–control studies from the US
predictors of depression in this study. Because the findings (HADS-A, 7.7; HADS-D, 6.0) , Germany (HADS-A, 8.2 ± 4.1;
[1]
vary across different regions, more studies are needed to HADS-D, 4.9 ± 3.8) , Singapore (HADS-A, 7.2; HADS-D,
[12]
confirm the factors influencing anxiety and depression in AD 5.0) , the Taiwan region, and China mainland (HADS-A, 9.1
[32]
patients currently. Nevertheless, our results further support ± 3.2; HADS-D, 5.8 ± 3.6) . In our results (HADS-A, 4.89;
[31]
the presence of a high frequency of psychosocial comorbidity HADS-D, 7.89), HADS-A scores were lower than other studies,
in AD patients and suggest the importance of screening for and HADS-D scores were higher than previous studies. De
depressive and anxiety symptoms in AD patients. Vaus et al. (2018) reported the differences in the explanation

Volume 1 Issue 1 (2023) 6 https://doi.org/10.36922/jcbp.0956