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Journal of Clinical and
            Basic Psychosomatics                                    Prevalence of skin disorders in patients with schizophrenia




            Table 1. Sociodemographic and clinical profile of the study population
             Sociodemographic and clinical variables      Male (n=66)            Female (n=36)             P
            Mean age in years (SD)                        39.30 (12.12)           39.63 (10.60)           0.88*
            Mean years of education (SD)                  10.34 (3.79)            10.08 (5.22)            0.76*
            Mean duration of schizophrenia in months (SD)  142.53 (108.79)        119.02 (92.67)          0.27*
            Mean BMI (SD)                                 25.10 (4.57)            26.02 (5.34)            0.36*
            Mean waist circumference in cm (SD)           93.87 (10.76)           94.67 (15.10)            -
            No. of participants with hypertension (%)     19 (28.78)                9 (25)                0.68*
            Notes: Statistically significant if P<0.05 for *Independent samples t-test.

            Table 2. Most common diagnoses (>1 mention)        with greater alacrity, and the modest sample size. However,
                                                               most participants did not volunteer any skin complaints,
             Diagnosis                                  n      and the findings are a product of careful dermatological
            Melasma                                     9      examination.
            Acne vulgaris                               9        The sociodemographic information and clinical
            Cherry angioma                              8      profile of the study group were fairly representative of the
            Melanocytic nevi                            8      population of treatment-seeking, community-living, and
            Onychomycosis                               6      stable patients with schizophrenia visiting the outpatient
            Freckles                                    6      clinic of the Department of Psychiatry. Furthermore,
            Acanthosis nigricans                        4      the prevalence of hypertension, obesity, and abdominal
            Rosacea                                     3      obesity in the present study is consistent with previous
                                                                                  [16]
            Tinea cruris                                3      reports from this center .
            Polymorphous light eruption                 3        Our study reveals a high prevalence of skin disorders
            Beau’s lines                                3      in patients with schizophrenia, similar to, although slightly
                                                                                                           [12]
            Folliculitis                                3      lower than, the findings of a study conducted in Taiwan .
            Melanonychia                                3      The  prevalence  of  skin  disorders  in this  population  is
                                                               higher than that observed in the general population in
            Post varicella scarring                     3      rural India  but lower than the prevalence reported in
                                                                        [17]
            Xerosis                                     3
                                                               clinic-based studies of patient populations, such as those
            Androgenic alopecia                         2      with diabetes . As pointed out earlier, there is a paucity
                                                                          [18]
            Dermatitis passivata                        2      of systematic studies with regard to skin disorders in
            Tinea corporis                              2      patients  with  schizophrenia,  making  direct  comparisons
                                                                        [19]
            Post inflammatory hyperpigmentation         2      challenging .
            Lichen simplex                              2        Our findings reveal several notable observations.
            Seborrheic keratosis                        2      The most common group of disorders observed in our
            Psoriasis                                   2      study was photo-aggravated dermatoses (29.41%). While
                                                               photosensitivity has been recognized as a side-effect of
                                                               typical antipsychotics, there is increasing recognition of
            4. Discussion                                      its frequency with the use of newer atypical antipsychotics
                                                                    [20]
            Schizophrenia is known to be associated with a high   as well . Interestingly, the study conducted in Taiwan did
            degree of comorbidity with various non-communicable   not report any instances of photosensitivity reactions in
            and communicable diseases. However, the comorbidity   their sample . Photosensitivity reactions can have various
                                                                         [12]
            of schizophrenia with skin disorders remains relatively   manifestations and severities. Our study demonstrates
            understudied. Thus, this study aimed to contribute to the   that in an Indian population with schizophrenia receiving
            existing literature in this area. The results of the present   antipsychotics,  photosensitivity reactions  are  common.
            study should be discussed with reference to the participants   Early identification and treatment of these disorders are
            being health-care-seeking patients in a tertiary hospital, the   needed, as facial pigmentary disorders associated with
            absence of a control group, the possibility of a selection bias   photosensitivity can significantly impair quality of life and
            where patients with skin complaints may have consented   require long-term management.


            Volume 1 Issue 2 (2023)                         3                        https://doi.org/10.36922/jcbp.1001
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