Page 84 - JCBP-2-1
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Journal of Clinical and
            Basic Psychosomatics                                                   Screening for SSD-B criteria in China



              The physical component of SSD can escalate the   diagnostic accuracy and ultimately enhancing the overall
            severity and complexity of depression and anxiety   management of SSD.
            disorders,  resulting  in  heightened  psychological  distress   However, the research is subject to limitations inherent
            and functional impairment [14,33] . A comparative study on   in cross-sectional studies with large sample sizes. One
            health anxiety between SSD and illness anxiety disorder   notable limitation is the absence of SCID-5-RV gold
            (IAD) revealed that individuals with SSD experience   standard diagnostic  interviews  with patients  to confirm
            more  pronounced  functional  impairment  are  more   SSD diagnosis. In addition, the selection of departments
            prone to panic and generalized anxiety disorder, and seek   where SSD patients visit more frequently may introduce
            medical consultation more frequently than IAD patients.   biases in the results, potentially leading to an offset in the
            In other words, SSD is associated with heightened health   findings. The current study mainly focused on exploring
            anxiety due to disease [14,34] . In our studies, the results have   the use of time spent worrying about physical discomfort
            indicated that WI-8 is an effective predictor of symptom-  and the WI-8  scale  as  standards for  measuring  SSD
            related cognitive behavior. In the previous multicenter   psychological behavior. Consequently, no further analysis
            study, WI-8 (r  = 0.823,  P  < 0.01), time spent worrying   was conducted on anxiety and depression. The specificity of
            about physical symptoms (r  = 0.570,  P  < 0.01), and   the joint predictive diagnosis results from the ROC analysis
            PHQ-15 (r = 0.519, P < 0.01) were all significant predictors   did  not  exhibit  improvement.  This  finding  suggests  that
            in a multiple regression analysis. The findings indicate that   outpatient patients can undergo more effective screening
            anxiety related to one’s health, the duration of attention   for SSD, reducing the likelihood of overlooking suspicious
            to symptoms, and the number and severity of physical   cases. However, caution should be exercised regarding the
            symptoms all exert a decisive impact on SSD–B criteria.   potential situation of “over-diagnosis.” In future research
            However, in the comparative study, PHQ-15 was not   endeavors, researchers are encouraged to employ the
            included in the equation. This omission may be related to   gold standard for diagnosis and broaden the scope of
            the fact that patients with severe physical symptoms tend   targeted departments. This approach aims to attain a more
            to prefer non-psychiatric clinics.                 accurate and comprehensive understanding of temporal
              In addition, to further predict the diagnosis of SSD–B   quantification values or other meaningful indicators that
            criteria using the WI-8 scale and time spent worrying about   can effectively screen SSD–B criteria.
            physical symptoms,  we separately calculated  their ROC
            curves. Both of our studies indicated a higher AUC and   5. Conclusion
            a greater predictive accuracy for the WI-8 scale compared   This  study  presents  a  simple,  cost-effective,  rapid,  and
            to time alone. In the previous multicenter study, when   direct method for clinical doctors to assess the SSD–B
            the WI-8 scale and time were combined for predictive   criteria, which can be easily used even by non-psychiatric
            diagnosis,  the  prediction accuracy reached its  peak   specialists. The combination of WI-8 and time spent
            (AUC =0.921), with an improved sensitivity of 88.6%. This   worrying about physical symptoms demonstrates
            enhancement facilitates more effective screening of SSD–B   noteworthy screening and predictive diagnostic values
            criteria.  As  demonstrated  in  our  earlier  research ,  the   for SSD-12. In clinical consultations, if patients report
                                                    [25]
            WI-8 has a determined cutoff value of 19, and the current   spending more than 1.25 h/day attending to their physical
            study established a time cutoff value of 1.25 h (sensitivity:   symptoms or if their WI-8 scale score equals or exceeds 19,
            68.3%, specificity: 84.5%). Combining these two measures   and they have experienced at least one somatic symptom
            can be utilized for screening of SSD–B criteria. Our   persistently for more than 6  months, suspicions of SSD
            comparative study closely aligns with the results of   should be raised, warranting further evaluations.
            previous  multicenter  studies,  highlighting  the  stability
            of time and the WI-8 as joint predictors. This research   Acknowledgments
            holds favorable representativeness and generalization   We thank all the participants.
            in the three aspects: (i) it provides valuable insights into
            predicting  and  understanding  SSD  criteria,  specifically   Funding
            focusing on the Chinese context; (ii) by addressing the
            unique  cultural  and  societal  aspects  relevant  to  China,   This study was financially supported by National Natural
            this research adds significant depth to the understanding   Science Foundation of China Youth Fund (82001313).
            of SSD and paves the way for targeted interventions and   Conflict of interest
            support for individuals experiencing somatic symptoms in
            this region; (iii) it offers a promising avenue for improving   The authors declare they have no competing interests.



            Volume 2 Issue 1 (2024)                         8                        https://doi.org/10.36922/jcbp.1813
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