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Journal of Clinical and

                                                                   Basic Psychosomatics



                                        BRIEF REPORT
                                        Psychological high-risk factors for acne: A

                                        prospective and cohort study



                                                            2†
                                                   1†
                                        Yidan Zhang , Yi Wang , He Zeng , Yi Zhang , Nan Wu , and Haiping Zhang *
                                                                      3
                                                                                                          1
                                                                                       1
                                                                               1
                                        1 Department of Dermatology, Xuanwu Hospital, Capital Medical University, Beijing, China
                                        2 Department of Pediatric Intensive Care Unit, Beijing Children’s Hospital, Capital Medical University,
                                        National Center for Children’s Health, Beijing, China
                                        3 Department of Endocrinology, Genetics and Metabolism, Beijing Children’s Hospital, Capital
                                        Medical University, National Center for Children’s Health, Beijing, China
                                        Abstract

                                        The present study explored the role of psychological factors and sleep quality in
                                        acne. Participants were recruited to assess the occurrence of acne monthly, and
                                        depression,  anxiety,  and  sleep  status  were  evaluated  using  the  patient  health
                                        questionnaire-9, self-rating anxiety  scale, and  the pittsburgh sleep quality index.
                                        Generalized estimating equations compared the effects of different factors on
                                        the occurrence of acne. Depression and moderate sleep quality were significantly
                                        related to acne (P < 0.05). Meanwhile, depression and sleep quality (moderate and
                                        poor) were significantly associated with inflammatory acne (P < 0.05). In conclusion,
                                        depression and sleep problems may be involved in the pathogenesis of acne,
                                        especially inflammatory acne. We recommend paying more attention to depression
            † These authors contributed equally   and sleep quality in patients to prevent acne.
            to this work
            *Corresponding author:
            Haiping Zhang               Keywords: Acne; Depression; Anxiety; Sleep quality
            (zhanghaiping@xwhosp.org)
            Citation: Zhang Y, Wang Y, Zeng H,
            et al., 2024, Psychological high-risk
            factors for acne: A prospective   1. Introduction
            and cohort study. J Clin Basic
            Psychosom, 2(1): 0944.      Acne is a common chronic inflammatory disease involving the sebaceous glands, with
            https://doi.org/10.36922/jcbp.0944   a prevalence of up to 73.5% in adolescents . Due to its specific impact on appearance,
                                                                          [1]
            Received: May 12, 2023      acne can cause many negative experiences in the daily life. The typical lesions of acne
                                        include pimples, papules, pustules, nodules, and cysts, of which the appearance of papules,
            Accepted: June 26, 2023
                                        pustules, nodules, and cysts is closely related to the local inflammatory response, and
            Published Online: July 10, 2023  psychological factors can promote inflammatory skin disease [2-5] . Studies have also shown
                                                                                             [6]
            Copyright: © 2023 Author(s).   that acne patients have poorer mental health than those without acne  and are more likely
            This is an Open Access article   to experience social anxiety and depression . However, no studies provide substantial
                                                                           [7]
            distributed under the terms of the
            Creative Commons Attribution   evidence as to whether there is a causal relationship between emotional status and acne
            License, permitting distribution,   occurrence. This study aimed to investigate the effect of emotional state and sleep quality
            and reproduction in any medium,   on the occurrence of acne and to provide ideas for acne prevention and treatment.
            provided the original work is
            properly cited.             2. Materials and methods
            Publisher’s Note: AccScience
            Publishing remains neutral with   2.1. Participants
            regard to jurisdictional claims in
            published maps and institutional   A total of 169 participants aged 18 – 35  years were recruited through online social
            affiliations.               software, URL: www.wjx.cn. All participants signed statements of informed consent


            Volume 2 Issue 1 (2024)                         1                        https://doi.org/10.36922/jcbp.0944
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