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Journal of Clinical and
            Translational Research                                           Vaginal microbiota in menopause pathologies



            12. Conclusion                                     References

            The intestinal, urinary, and vaginal microbiomes form   1.   Muhleisen AL, Herbst-Kralovetz MM. Menopause and the
            an interconnected ecosystem whose alteration during   vaginal microbiome. Maturitas. 2016;91:42-50.
            menopause, primarily caused by estrogen deficiency,      doi: 10.1016/j.maturitas.2016.05.015
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            potentially ovarian cancer, through mechanisms involving   4.   De Oliveira NS, De Lima ABF, De Brito JCR, Sarmento ACA,
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            Acknowledgments                                       doi: 10.1097/JU.0000000000001940
                                                               7.   Naji A, Siskin D, Woodworth MH, Lee JR, Kraft CS,
            None.                                                 Mehta N. The role of the gut, urine, and vaginal microbiomes
            Funding                                               in the pathogenesis of urinary tract infection in women and
                                                                  consideration of microbiome therapeutics.  Open  Forum
            None.                                                 Infect Dis. 2024;11(9):ofae471.
                                                                  doi: 10.1093/ofid/ofae471
            Conflict of interest
                                                               8.   Barrea L, Verde L, Auriemma RS,  et al. Probiotics and
            The author declares no conflict of interest.          prebiotics: Any role in menopause-related diseases?  Curr
                                                                  Nutr Rep. 2023;12(1):83-97.
            Author contributions
                                                                  doi: 10.1007/s13668-023-00462-3
            This is a single-authored article.
                                                               9.   Kalia N, Singh J, Kaur M. Microbiota in vaginal health and
            Ethics approval and consent to participate            pathogenesis of recurrent vulvovaginal infections: A critical
                                                                  review. Ann Clin Microbiol Antimicrob. 2020;19(1):5.
            Not applicable.
                                                                  doi: 10.1186/s12941-020-0347-4
            Consent for publication                            10.  Deka N, Hassan S, Seghal Kiran G, Selvin J. Insights into
            Not applicable.                                       the role of vaginal microbiome in women’s health. J Basic
                                                                  Microbiol. 2021;61(12):1071-1084.
            Availability of data                                  doi: 10.1002/jobm.202100421
            Not applicable.                                    11.  Ovalle A, Martínez MA. In: Guzmán E, editor. CAPÍTULO


            Volume 11 Issue 5 (2025)                        44                         doi: 10.36922/JCTR025150016
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