Page 50 - MI-1-2

Microbes & Immunity Host receptors in immunogenic cell death

cells. Science. 2020;368(6494):eaaz7548. Biochim Biophys Acta. 2006;1757(9):1371-1387.
doi: 10.1126/science.aaz7548 doi: 10.1016/j.bbabio.2006.06.014
116. Ding J, Wang K, Liu W, et al. Pore-forming activity and 127. Zong WX, Thompson CB. Necrotic death as a cell fate. Genes
structural autoinhibition of the gasdermin family. Nature. Dev. 2006;20(1):1-15.
2016;535(7610):111-116. doi: 10.1101/gad.1376506
doi: 10.1038/nature18590 128. Ashida H, Mimuro H, Ogawa M, et al. Cell death and
117. Liu X, Zhang Z, Ruan J, et al. Inflammasome-activated infection: A double-edged sword for host and pathogen
gasdermin D causes pyroptosis by forming membrane survival. J Cell Biol. 2011;195(6):931-942.
pores. Nature. 2016;535(7610):153-158. doi: 10.1083/jcb.201108081
doi: 10.1038/nature18629 129. Berube BJ, Bubeck Wardenburg J. Staphylococcus aureus
118. Jorgensen I, Miao EA. Pyroptotic cell death defends against α-toxin: Nearly a century of intrigue. Toxins (Basel).
intracellular pathogens. Immunol Rev. 2015;265:130-142. 2013;5(6):1140-1166.
doi: 10.1111/imr.12287 doi: 10.3390/toxins5061140
119. Brodsky IE, Palm NW, Sadanand S, et al. A Yersinia effector 130. Rao RV, Bredesen DE. Misfolded proteins, endoplasmic
protein promotes virulence by preventing inflammasome reticulum stress and neurodegeneration. Curr Opin Cell
recognition of the Type III secretion system. Cell Host Biol. 2004;16(6):653-662.
Microbe. 2010;7(5):376-387. doi: 10.1016/j.ceb.2004.09.012
doi: 10.1016/j.chom.2010.04.009 131. Paiva CN, Bozza MT. Are reactive oxygen species
120. Ratner D, Orning MPA, Proulx MK, et al. The Yersinia pestis always detrimental to pathogens? Antioxid Redox Signal.
effector YopM inhibits pyrin inflammasome activation. 2014;20(6):1000-1037.
PLoS Pathog. 2016;12(12):e1006035. doi: 10.1089/ars.2013.5447
doi: 10.1371/journal.ppat.1006035 132. Zhao D, Wu H, Li Y, et al. Effects of the pyrE deletion
121. Monroe KM, McWhirter SM, Vance RE. Identification of mutant from Bacillus thuringiensis on gut microbiota and
host cytosolic sensors and bacterial factors regulating the immune response of Spodoptera exigua. Front Microbiol.
Type I interferon response to Legionella pneumophila. PLoS 2023;14:1182699.
Pathog. 2009;5(11):e1000665. doi: 10.3389/fmicb.2023.1182699
doi: 10.1371/journal.ppat.1000665 133. Schuermans S, Kestens C, Marques PE. Systemic
122. Hou Y, Zeng H, Li Z, et al. Structural mechanisms of mechanisms of necrotic cell debris clearance. Cell Death Dis.
calmodulin activation of Shigella effector OspC3 to ADP- 2024;15(8):557.
riboxanate caspase-4/11 and block pyroptosis. Nat Struct doi: 10.1038/s41419-024-06947-5
Mol Biol. 2023;30(3):261-272.
134. Pinton P, Giorgi C, Siviero R, Zecchini E, Rizzuto R.
doi: 10.1038/s41594-022-00888-3 Calcium and apoptosis: ER-mitochondria Ca2+ transfer in
123. Li Z, Liu W, Fu J, et al. Shigella evades pyroptosis by the control of apoptosis. Oncogene. 2008;27(50):6407-6418.
arginine ADP-riboxanation of caspase-11. Nature. doi: 10.1038/onc.2008.308
2021;599(7884):290-295.
135. Bround MJ, Abay E, Huo J, et al. MCU-independent
doi: 10.1038/s41586-021-04020-1 Ca2+ uptake mediates mitochondrial Ca2+ overload and
124. Zhang K, Peng T, Tao X, et al. Structural insights into necrotic cell death in a mouse model of Duchenne muscular
caspase ADPR deacylization catalyzed by a bacterial effector dystrophy. Sci Rep. 2024;14:6751.
and host calmodulin. Mol Cell. 2022;82(24):4712-4726.e7. doi: 10.1038/s41598-024-57340-3
doi: 10.1016/j.molcel.2022.10.032 136. Fujiwara Y, Wada K, Kabuta T. Lysosomal degradation of
125. Liu Y, Zeng H, Hou Y, et al. Calmodulin binding activates intracellular nucleic acids-multiple autophagic pathways.
Chromobacterium CopC effector to ADP-riboxanate host J Biochem. 2017;161(2):145-154.
apoptotic caspases. mBio. 2022;13(3):e00690-22. doi: 10.1093/jb/mvw085
doi: 10.1128/mbio.00690-22 137. Nguyen JA, Yates RM. Better together: Current insights into
phagosome-lysosome fusion. Front Immunol. 2021;12:636078.
126. Festjens N, Vanden Berghe T, Vandenabeele P. Necrosis, a
well-orchestrated form of cell demise: Signalling cascades, 138. Zhu W, Tao L, Quick ML, Joyce JA, Qu JM, Luo ZQ. Sensing
important mediators and concomitant immune response. cytosolic RpsL by macrophages induces lysosomal cell

Volume 1 Issue 2 (2024) 44 doi: 10.36922/mi.4264