Page 46 - MI-1-2

Microbes & Immunity Host receptors in immunogenic cell death

2018;59:391-412. 35. Ko KH, Cha SB, Lee SH, et al. A novel defined TLR3
agonist as an effective vaccine adjuvant. Front Immunol.
doi: 10.1016/j.intimp.2018.03.002
2023;14:1075291.
24. Wang S, Zhang K, Huang Q, Meng F, Deng S. TLR4 signalling
in ischemia/reperfusion injury: A promising target for doi: 10.3389/fimmu.2023.1075291
linking inflammation, oxidative stress and programmed 36. Takaoka A, Wang Z, Choi MK, et al. DAI (DLM-1/ZBP1) is
cell death to improve organ transplantation outcomes. Front a cytosolic DNA sensor and an activator of innate immune
Immunol. 2024;15:1447060. response. Nature. 2007;448(7152):501-505.
doi: 10.3389/fimmu.2024.1447060 doi: 10.1038/nature06013
25. Hayashi F, Smith KD, Ozinsky A, et al. The innate immune 37. Ishikawa H, Barber GN. STING is an endoplasmic reticulum
response to bacterial flagellin is mediated by Toll-like adaptor that facilitates innate immune signalling. Nature.
receptor 5. Nature. 2001;410(6832):1099-1103. 2008;455(7213):674-678.
doi: 10.1038/35074106 doi: 10.1038/nature07317
26. Yang J, Yan H. TLR5: Beyond the recognition of flagellin. 38. Latz E, Schoenemeyer A, Visintin A, et al. TLR9 signals after
Cell Mol Immunol. 2017;14(12):1017-1019. translocating from the ER to CpG DNA in the lysosome. Nat
Immunol. 2004;5(2):190-198.
doi: 10.1038/cmi.2017.122
doi: 10.1038/ni1028
27. Yoon SI, Kurnasov O, Natarajan V, et al. Structural basis
of TLR5-flagellin recognition and signaling. Science. 39. Hornung V, Ablasser A, Charrel-Dennis M, et al. AIM2
2012;335(6070):859-864. recognizes cytosolic dsDNA and forms a caspase-1-activating
inflammasome with ASC. Nature. 2009;458(7237):514-518.
doi: 10.1126/science.1215584
doi: 10.1038/nature07725
28. Park BS, Lee JO. Recognition of lipopolysaccharide pattern
by TLR4 complexes. Exp Mol Med. 2013;45(12):e66-e66. 40. Li YP, Liu CR, Deng HL, et al. DNA methylation and single-
nucleotide polymorphisms in DDX58 are associated with
doi: 10.1038/emm.2013.97 hand, foot and mouth disease caused by enterovirus 71.
29. Kawai T, Akira S. Toll-like receptors and their crosstalk with PLoS Negl Trop Dis. 2022;16(1):e0010090.
other innate receptors in infection and immunity. Immunity. doi: 10.1371/journal.pntd.0010090
2011;34(5):637-650.
41. Miya TV, Groome MJ, de Assis Rosa D. TLR genetic variation
doi: 10.1016/j.immuni.2011.05.006 is associated with Rotavirus-specific IgA seroconversion
30. Loo YM, Gale M. Immune signaling by RIG-I-like receptors. in South African Black infants after two doses of Rotarix
Immunity. 2011;34(5):680-692. vaccine. Vaccine. 2021;39(48):7028-7035.
doi: 10.1016/j.immuni.2011.05.003 doi: 10.1016/j.vaccine.2021.10.051
31. Kanneganti TD, Özören N, Body-Malapel M, et al. Bacterial 42. Zhong Y, Kinio A, Saleh M. Functions of NOD-like receptors
RNA and small antiviral compounds activate caspase-1 in human diseases. Front Immunol. 2013;4:333.
through cryopyrin/Nalp3. Nature. 2006;440(7081):233-236. doi: 10.3389/fimmu.2013.00333
doi: 10.1038/nature04517 43. Davis BK, Wen H, Ting JPY. The inflammasome NLRs in
32. Song J, Li M, Li C, Liu K, Zhu Y, Zhang H. Friend or immunity, inflammation, and associated diseases. Annu Rev
foe: RIG- I like receptors and diseases. Autoimmun Rev. Immunol. 2011;29(1):707-735.
2022;21(10):103161. doi: 10.1146/annurev-immunol-031210-101405
doi: 10.1016/j.autrev.2022.103161 44. Franchi L, Warner N, Viani K, Nuñez G. Function of nod-
33. Najem MY, Rys RN, Laurance S, et al. Extracellular RNA like receptors in microbial recognition and host defense.
induces neutrophil recruitment via toll‐like receptor 3 Immunol Rev. 2009;227(1):106-128.
during venous thrombosis after vascular injury. J Am Heart doi: 10.1111/j.1600-065X.2008.00734.x
Assoc 2024;13:e034492.
45. Zhao Y, Yang J, Shi J, et al. The NLRC4 inflammasome
doi: 10.1161/JAHA.124.034492 receptors for bacterial flagellin and type III secretion
apparatus. Nature. 2011;477(7366):596-600.
34. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition
of double-stranded RNA and activation of NF-κB by Toll-like doi: 10.1038/nature10510
receptor 3. Nature. 2001;413(6857):732-738.
46. Wright EK, Goodart SA, Growney JD, et al. Naip5 affects
doi: 10.1038/35099560 host susceptibility to the intracellular pathogen Legionella

Volume 1 Issue 2 (2024) 40 doi: 10.36922/mi.4264