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Microbes & Immunity Genetic therapy with HSV-1 vectors

References 14. Aurelian L. HSV-induced apoptosis in herpes encephalitis.
Curr Top Microbiol Immunol. 2005;289:79-111.
1. McGeoch DJ, Dalrymple MA, Davison AJ, et al. The
complete DNA sequence of the long unique region in doi: 10.1007/3-540-27320-4_4
the genome of herpes simplex virus type 1. J Gen Virol. 15. Whitley RJ, Roizman B. Herpes simplex virus infections.
1988;69(Pt 7):1531-1574. Lancet. 2001;357(9267):1513-1518.
doi: 10.1099/0022-1317-69-7-1531 doi: 10.1016/S0140-6736(00)04638-9
2. Roizman B, Baines J. The diversity and unity of Herpesviridae. 16. Daheshia M, Feldman LT, Rouse BT. Herpes simplex virus
Comp Immunol Microbiol Infect Dis. 1991;14(2):63-79. latency and the immune response. Curr Opin Microbiol.
doi: 10.1016/0147-9571(91)90122-t 1998;1(4):430-435.

3. Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex doi: 10.1016/s1369-5274(98)80061-1
viruses. Clin Infect Dis. 1998;26(3):541-553; quiz 554-5. 17. Arduino PG, Porter SR. Herpes simplex virus type 1
4. Marozin S, Prank U, Sodeik B. Herpes simplex virus type 1 infection: Overview on relevant clinico-pathological
infection of polarized epithelial cells requires microtubules features. J Oral Pathol Med. 2008;37(2):107-121.
and access to receptors present at cell-cell contact sites. doi: 10.1111/j.1600-0714.2007.00586.x
J Gen Virol. 2004;85(Pt 4):775-786.
18. Roizman B. HSV gene functions: What have we learned that
doi: 10.1099/vir.0.19530-0 could be generally applicable to its near and distant cousins?
5. Babb R, Huang CC, Aufiero DJ, Herr W. DNA recognition by Acta Virol. 1999;43(2-3):75-80.
the herpes simplex virus transactivator VP16: A novel DNA- 19. Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B. Friendly
binding structure. Mol Cell Biol. 2001;21(14):4700-4712. fire: Redirecting herpes simplex virus-1 for therapeutic
doi: 10.1128/MCB.21.14.4700-4712.2001 applications. Clin Microbiol Infect. 2002;8(9):551-563.
6. Watanabe D. Medical application of herpes simplex virus. doi: 10.1046/j.1469-0691.2002.00432.x.
J Dermatol Sci. 2010;57(2):75-82. 20. Goins WF, Wolfe D, Krisky DM, et al. Delivery using herpes

doi: 10.1016/j.jdermsci.2009.10.014 simplex virus: An overview. Methods Mol Biol. 2004;246:257-299.
7. Boehmer PE, Lehman IR. Herpes simplex virus DNA doi: 10.1385/1-59259-650-9:257
replication. Annu Rev Biochem. 1997;66:347-384. 21. Epstein AL. HSV-1-derived recombinant and amplicon
doi: 10.1146/annurev.biochem.66.1.347 vectors for preventive or therapeutic gene transfer: An
overview. Gene Ther. 2005;12 Suppl 1:S153.
8. Roizman B. The function of herpes simplex virus genes:
A primer for genetic engineering of novel vectors. Proc Natl 22. Maguire-Zeiss KA, Bowers WJ, Federoff HJ. HSV vector-
Acad Sci U S A. 1996;93(21):11307-11312. mediated gene delivery to the central nervous system. Curr
Opin Mol Ther. 2001;3(5):482-490.
doi: 10.1073/pnas.93.21.11307
23. Glorioso JC, Fink DJ. Herpes vector-mediated gene transfer
9. Elliott G, O’Hare P. Cytoplasm-to-nucleus translocation of in treatment of diseases of the nervous system. Annu Rev
a herpesvirus tegument protein during cell division. J Virol. Microbiol. 2004;58:253-271.
2000;74(5):2131-2141.
doi: 10.1146/annurev.micro.58.030603.123709
doi: 10.1128/jvi.74.5.2131-2141.2000
24. Markert JM, Gillespie GY, Weichselbaum RR, Roizman B,
10. Jackson SA, DeLuca NA. Relationship of herpes simplex virus Whitley RJ. Genetically engineered HSV in the treatment of
genome configuration to productive and persistent infections. glioma: A review. Rev Med Virol. 2000;10(1):17-30.
Proc Natl Acad Sci U S A. 2003;100(13):7871-7876.
doi: 10.1002/(sici)1099-1654(200001/02)10:1<17:aid-rmv2
doi: 10.1073/pnas.1230643100
58>3.0.co;2-g
11. Steiner I, Kennedy PG. Molecular biology of herpes simplex 25. Niranjan A, Wolfe D, Fellows W, et al. Gene transfer to
virus type 1 latency in the nervous system. Mol Neurobiol. glial tumors using herpes simplex virus. Methods Mol Biol.
1993;7(2):137-159.
2004;246:323-337.
doi: 10.1007/BF02935640
doi: 10.1385/1-59259-650-9:323
12. Roizman B, Whitley RJ. The nine ages of herpes simplex 26. Karpoff HM, Kooby D, D’Angelica M, et al. Efficient
virus. Herpes. 2001;8(1):23-27.
cotransduction of tumors by multiple herpes simplex
13. Rouse BT. Pathogenesis of the herpesviruses. Lab Anim Sci. vectors: Implications for tumor vaccine production. Cancer
1993;43(1):11-14. Gene Ther. 2000;7(4):581-588.

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