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Microbes & Immunity Understanding lung development, health, and diseases

regulation of Wnt signaling. Cell Stem Cell. 2017;20:844-857. 61. Marri PR, Stern DA, Wright AL, Billheimer D, Martinez FD.
Asthma-associated differences in microbial composition of
doi: 10.1016/j.stem.2017.03.001
induced sputum. J Allergy Clin Immunol. 2013;131:346-352.
50. Basil MC, Alysandratos KD, Kotton DN, Morrisey EE. Lung doi: 10.1016/j.jaci.2012.11.013
repair and regeneration: Advanced models and insights into
human disease. Cell Stem Cell. 2024;31:439-454. 62. Kleniewska P, Pawliczak R. Can probiotics be used in the
prevention and treatment of bronchial asthma? Pharmacol
doi: 10.1016/j.stem.2024.02.009
Rep. 2024;76:740-753.
51. Xi Y, Kim T, Brumwell AN, et al. Local lung hypoxia doi: 10.1007/s43440-024-00618-0
determines epithelial fate decisions during alveolar
regeneration. Nat Cell Biol. 2017;19:904-914. 63. Garcia-Nuñez M, Millares L, Pomares X, et al. Severity-related
changes of bronchial microbiome in chronic obstructive
doi: 10.1038/ncb3580 pulmonary disease. J Clin Microbiol. 2014;52:4217-4223.
52. Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles doi: 10.1128/JCM.01967-14
harbor a unique airway stem cell population that localizes
to the bronchoalveolar duct junction. Am J Pathol. 64. Wu D, Hou C, Li Y, et al. Analysis of the bacterial community
2002;161:173-182. in chronic obstructive pulmonary disease sputum samples
by denaturing gradient gel electrophoresis and real-time
doi: 10.1016/S0002-9440(10)64169-7 PCR. BMC Pulm Med. 2014;14:179.
53. Faure S, de Santa Barbara P. Molecular embryology of the doi: 10.1186/1471-2466-14-179
foregut. J Pediatr Gastroenterol Nutr. 2011;52:S2-S3.
65. Carvalho JL, Miranda M, Fialho AK, et al. Oral feeding
doi: 10.1097/MPG.0b013e3182105a1a with probiotic Lactobacillus rhamnosus attenuates cigarette
54. Hou K, Wu ZX, Chen XY, et al. Microbiota in health and smoke-induced COPD in C57Bl/6 mice: Relevance to
diseases. Signal Transduct Target Ther. 2022;23:135. inflammatory markers in human bronchial epithelial cells.
PLoS One. 2020;15:e0225560.
doi: 10.1038/s41392-022-00974-4
doi: 10.1371/journal.pone.0225560
55. Moffatt MF, Cookson WO. The lung microbiome in health
and disease. Clin Med. (Lond). 2017;17:525-529. 66. Hurley MN, Ariff AH, Bertenshaw C, Bhatt J, Smyth AR.
Results of antibiotic susceptibility testing do not influence
doi: 10.7861/clinmedicine.17-6-525 clinical outcome in children with cystic fibrosis. J Cyst
56. Man MA, Ungur RA, Motoc NS, Pop LA, Berindan-Neagoe I, Fibros. 2012;11:288-292.
Ruta VM. Lung microbiota in idiopathic pulmonary fibrosis, doi: 10.1016/j.jcf.2012.02.006
hypersensitivity pneumonitis, and unclassified interstitial 67. Wu BG, Segal LN. Lung microbiota and its impact on the
lung diseases: A preliminary pilot study. Diagnostics (Basel). mucosal immune phenotype. Microbiol Spectr. 2017;5(3).
2023;13:3157.
doi: 10.1128/microbiolspec.BAD-0005-2016
doi: 10.3390/diagnostics13193157
68. Smith AL, Fiel SB, Mayer-Hamblett N, Ramsey B, Burns JL.
57. Aung HH, Sivakumar A, Gholami SK, Venkateswaran SP, Susceptibility testing of Pseudomonas aeruginosa isolates and
Gorain B, Shadab Md. An overview of the anatomy and clinical response to parenteral antibiotic administration: Lack
physiology of the lung. In: Nanotechnology-based Targeted of association in cystic fibrosis. Chest. 2003;123:1495-1502.
Drug Delivery Systems for Lung Cancer. United States:
Academic Press; 2019. p. 1-20. doi: 10.1378/chest.123.5.1495
doi: 10.1016/B978-0-12-815720-6.00001-0 69. Coffey MJ, Garg M, Homaira N, Jaffe A, Ooi CY. Probiotics
for people with cystic fibrosis. Cochrane Database Syst Rev.
58. Lloyd CM, Hessel EM. Functions of T cells in asthma: More 2020;22:CD012949.
than just T(H) 2 cells . Nat Rev Immunol. 2010;10:838-848. doi: 10.1002/14651858.CD012949.pub2
doi: 10.1038/nri2870
70. Collard HR, Moore BB, Flaherty KR, et al. Acute exacerbation
59. Gollwitzer ES, Saglani S, Trompette A, et al. Lung microbiota of idiopathic pulmonary fibrosis. An international working
promotes tolerance to allergens in neonates via PD-L1. Nat group report. Am J Respir Crit Care Med. 2007;194:636-643.
Med. 2014;20:642-647.
doi: 10.1164/rccm.201604-0801CI
doi: 10.1038/nm.3568
71. Han ML, Zhou Y, Murray S. Lung microbiome and disease
60. Hilty M, Burke C, Pedro H, et al. Disordered microbial progression in idiopathic pulmonary fibrosis: An analysis of
communities in asthmatic airways. PLoS One. 2010;5:e8578. the COMET study. Lancet Respir Med. 2014;2:548-556.
doi: 10.1371/journal.pone.0008578 doi: 10.1016/S2213-2600(14)70069-4

Volume 2 Issue 3 (2025) 58 doi: 10.36922/mi.7719