Page 64 - MI-2-3
P. 64
Microbes & Immunity Understanding lung development, health, and diseases
2021;282(4):600-611. 14. Chinoy MR, Graybill MM, Miller SA, Lang CM, Kauffman
GL. Angiopoietin-1 and VEGF in vascular development and
doi: 10.1002/jmor.21330
angiogenesis in hypoplastic lungs. Am J Physiol Lung Cell
3. Zacharias WJ, Frank DB, Zepp JA, et al. Regeneration of Mol Physiol. 2002;283:L60-L66.
the lung alveolus by an evolutionarily conserved epithelial
progenitor. Nature. 2018;555:251-255. doi: 10.1152/ajplung.00317.2001
doi: 10.1038/nature25786 15. Pauling MH, Vu TH. Mechanisms and regulation of lung
vascular development. Curr Top Dev Biol. 2004;64:73-99.
4. Domyan ET, Ferretti E, Throckmorton K, Mishina Y,
Nicolis SK, Sun X. Signaling through BMP receptors doi: 10.1016/S0070-2153(04)64005-1
promotes respiratory identity in the foregut via repression 16. Kadzik RS, Morrisey EE. Directing lung endoderm
of Sox2. Development. 2011;138(5):971-981. differentiation in pluripotent stem cells. Cell Stem Cell.
doi: 10.1242/dev.0594694 2012;10(4):355-361.
5. Schittny JC. Development of the lung. Cell Tissue Res. doi: 10.1016/j.stem.2012.03.013
2017;367:427-444. 17. Han L, Chaturvedi P, Kishimoto K, et al. Single cell
doi: 10.1007/s00441-016-2545-0 transcriptomics identifies a signaling network coordinating
endoderm and mesoderm diversification during foregut
6. Goss AM, Tian Y, Tsukiyama T, et al. Wnt2/2b and beta- organogenesis. Nat Commun. 2020;11(1):4158.
catenin signaling are necessary and sufficient to specify lung
progenitors in the foregut. Dev Cell. 2009;17:290-298. doi: 10.1038/s41467-020-17968-x
doi: 10.1016/j.devcel.2009.06.005 18. Rankin SA, Han L, McCracken KW, et al. A retinoic acid-
hedgehog cascade coordinates mesoderm-inducing signals
7. Chytil F. Retinoids in lung development. FASEB J. and endoderm competence during lung specification. Cell
1996;10:986-992. Rep. 2016;16(1):66-78.
doi: 10.1096/fasebj.10.9.8801181 doi: 10.1016/j.celrep.2016.05.060
8. McGowan S, Jackson SK, Jenkins-Moore M, Dai HH, 19. Nikolić M, Sun D, Rawlins E. Human lung development:
Chambon P, Snyder JM. Mice bearing deletions of retinoic Recent progress and new challenges. Development.
acid receptors demonstrate reduced lung elastin and alveolar 2018;145:dev163485.
numbers. Am J Respir Cell Mol Biol. 2000;23:162-167.
doi: 10.1242/dev.163485
doi: 10.1165/ajrcmb.23.2.3904
20. Desai TJ, Brownfield DG, Krasnow MA. Alveolar progenitor
9. Alescio T, Cassini A. Induction in vitro of tracheal buds by and stem cells in lung development, renewal and cancer.
pulmonary mesenchyme grafted on tracheal epithelium. Nature. 2014;507(7491):190-194.
J Exp Zool. 1962;150:83-94.
doi: 10.1038/nature12930
doi: 10.1002/jez.1401500202
21. David M, Lamas-Pinheiro R, Henriques-Coelho T. Prenatal
10. Fox E, Shojaie S, Wang J, et al. Three-dimensional culture and postnatal management of congenital pulmonary airway
and FGF signaling drive differentiation of murine malformation. Neonatology. 2016;110(2):101-115.
pluripotent cells to distal lung epithelial cells. Stem Cells
Dev. 2015;24:21-35. doi: 10.1159/000440894
doi: 10.1089/scd.2014.0227 22. Nabhan AN, Brownfield DG, Harbury PB, et al. Single-
cell Wnt signaling niches maintain stemness of alveolar
11. Mullassery D, Smith NP. Lung development. Semin Pediatr type 2 cells. Science. 2018;359(6380):1118-1123.
Surg. 2015;24:152-155.
doi: 10.1126/science.aam6603
doi: 10.1053/j.sempedsurg.2015.01.011
23. Morton SU, Brodsky D. Fetal physiology and the transition
12. Yin Y, Wang F, Ornitz DM. Mesothelial-and epithelial- to extrauterine life. Clin Perinatol. 2016;43:395-407.
derived FGF9 have distinct functions in the regulation of
lung development. Development. 2011;138:3169-3177. doi: 10.1016/j.clp.2016.04.001
doi: 10.1242/dev.065110 24. Elias N, O’Brodovich H. Clearance of fluid from airspaces of
newborns and infants. Neoreviews. 2006;7:88-94.
13. Wang Y, Tian Y, Morley MP, et al. Development and
regeneration of Sox2 endoderm progenitors are regulated doi: 10.1542/neo.7-2-e88
+
by a Hdac1/2-Bmp4/Rb1 regulatory pathway. Dev Cell. 25. O’Donnell CP, Kamlin CO, Davis PG. Crying and breathing
2013;24:345-358.
by extremely preterm infants immediately after birth.
doi: 10.1016/j.devcel.2013.01.012 J Pediatr. 2010;156:846-847.
Volume 2 Issue 3 (2025) 56 doi: 10.36922/mi.7719

